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Protein
Submitted name:

KRT8 protein

Gene

KRT8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
KRT8 proteinImported
Gene namesi
Name:KRT8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ969I0.
PeptideAtlasiQ969I0.
PRIDEiQ969I0.

Structurei

3D structure databases

ProteinModelPortaliQ969I0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili26 – 74Sequence analysisAdd BLAST49
Coiled coili82 – 116Sequence analysisAdd BLAST35
Coiled coili182 – 262Sequence analysisAdd BLAST81

Sequence similaritiesi

Belongs to the intermediate filament family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IG4R. Eukaryota.
ENOG410YY6B. LUCA.
HOVERGENiHBG013015.

Family and domain databases

InterProiView protein in InterPro
IPR001664. IF.
IPR018039. Intermediate_filament_CS.
IPR003054. Keratin_II.
PANTHERiPTHR23239. PTHR23239. 1 hit.
PfamiView protein in Pfam
PF00038. Filament. 1 hit.
PRINTSiPR01276. TYPE2KERATIN.
SMARTiView protein in SMART
SM01391. Filament. 1 hit.
PROSITEiView protein in PROSITE
PS00226. IF. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q969I0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LETKWSLLQQ QKTARSNMDN MFESYINNLR RQLETLGQEK LKLEAELGNM
60 70 80 90 100
QGLVEDFKNK YEDEINKRTE MENEFVLIKK DVDEAYMNKV ELESRLEGLT
110 120 130 140 150
DEINFLRQLY EEEIRELQSQ ISDTSVVLSM DNSRSLDMDS IIAEVKAQYE
160 170 180 190 200
DIANRSRAEA ESMYQIKYEE LQSLAGKHGD DLRRTKTEIS EMNRNISRLQ
210 220 230 240 250
AEIEGLKGQR ASLEAAIADA EQRGELAIKD ANAKLSELEA ALQRAKQDMA
260 270 280 290 300
RQLREYQELM NVKLALDIEI ATYRKLLEGE ESRLESGMQN MSIHTKTTSG
310 320 330 340 350
YAGGLSSAYG GLTSPGLSYS LGSSFGSGAG SSSFSRTSSS RAVVVKKIET
360
RDGKLVSESS DVLPK
Length:365
Mass (Da):41,108
Last modified:May 24, 2005 - v2
Checksum:i57CD83091D0635E8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC011373 mRNA. Translation: AAH11373.2.
UniGeneiHs.533782.
Hs.708445.

Similar proteinsi

Entry informationi

Entry nameiQ969I0_HUMAN
AccessioniPrimary (citable) accession number: Q969I0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.