Q967M2 (Q967M2_GIAIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Adenine phosphoribosyltransferase EMBL AAK56310.1
Organism	Giardia intestinalis (Giardia lamblia) EMBL AAK56310.1
Taxonomic identifier	5741 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Fornicata › Diplomonadida › Hexamitidae › Giardiinae › Giardia

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Glycosyltransferase EMBL AAK56310.1 Transferase
Technical term	3D-structure PDB 1L1R PDB 1L1Q
Gene Ontology (GO)
Biological_process	nucleoside metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	100	1	Proton donor/acceptor PDB 1L1R
	Site	63	1	Transition state stabilizer PDB 1L1R

Sequences

	Sequence		Length	Mass (Da)
	Q967M2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: E9426D7975C0CE5C	FASTA	180	19,436
	10 20 30 40 50 60 MTMSVADAHA LIKTIPDFPT KGIAFKDLSD ILSTPAALDA VRKEVTAHYK DVPITKVVGI 70 80 90 100 110 120 ESRGFILGGI VANSLGVGFV ALRKAGKLPG DVCKCTFDME YQKGVTIEVQ KRQLGPHDVV 130 140 150 160 170 180 LLHDDVLATG GTLLAAIELC ETAGVKPENI YINVLYEIEA LKGREKVGQK CTRLFSVIRE

References

[1]	"The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties." Sarver A.E., Wang C.C. J. Biol. Chem. 277:39973-39980(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration." Shi W., Sarver A.E., Wang C.C., Tanaka K.S., Almo S.C., Schramm V.L. J. Biol. Chem. 277:39981-39988(2002) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS), ACTIVE SITE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF378363 mRNA. Translation: AAK56310.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1L1Q	X-ray	1.85	A	1-180	[»]
1L1R	X-ray	1.95	A	1-180	[»]

ProteinModelPortal

Q967M2.

SMR

Q967M2. Positions 2-180.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Enzyme and pathway databases

BRENDA

2.4.2.7. 322.

Family and domain databases

InterPro

IPR000836. PRibTrfase_dom.
[Graphical view]

Pfam

PF00156. Pribosyltran. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q967M2.

Entry information

Entry name

Q967M2_GIAIN

Accession

Primary (citable) accession number: Q967M2
Secondary accession number(s): A8BXA3

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	April 3, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)