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Protein

Replication enhancer protein

Gene

AC3

Organism
Cabbage leaf curl virus (isolate Jamaica) (CaLCuV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Increases viral DNA accumulation. Enhances infectivity and symptom expression (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interaction

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancer protein
Short name:
REn
Alternative name(s):
15.6 kDa protein
Protein AC3
Protein AL3
Gene namesi
ORF Names:AC3, AL3
OrganismiCabbage leaf curl virus (isolate Jamaica) (CaLCuV)
Taxonomic identifieri345184 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus
Virus hostiBrassica oleracea (Wild cabbage) [TaxID: 3712]
Proteomesi
  • UP000007622 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003236821 – 132Replication enhancer proteinAdd BLAST132

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement (By similarity).By similarity

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q96702-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRTGESIT VAQAENSVFI WEVPNPLYFR IQRVEDPLYT RTRIYHIQVR
60 70 80 90 100
FNHNLRKALD LRKAYFNFQV WTTSMRASGP TYLSRFKCLV MSHLDNLGVI
110 120 130
GINHVIRAVR FATDRSYVTH VHENHVINFK IY
Length:132
Mass (Da):15,630
Last modified:February 1, 1997 - v1
Checksum:iF87CE9812F9837D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65529 Genomic DNA. Translation: AAB17961.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65529 Genomic DNA. Translation: AAB17961.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiREN_CALCV
AccessioniPrimary (citable) accession number: Q96702
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.