Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L7a

Gene

rpl-7A

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • calmodulin binding Source: WormBase
  • RNA binding Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionCalmodulin-binding, Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L7a
Gene namesi
Name:rpl-7A
ORF Names:Y24D9A.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY24D9A.4a; CE27398; WBGene00004419; rpl-7A.
Y24D9A.4c; CE30401; WBGene00004419; rpl-7A.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001367562 – 26560S ribosomal protein L7aAdd BLAST264

Proteomic databases

EPDiQ966C6.
PaxDbiQ966C6.
PeptideAtlasiQ966C6.
PRIDEiQ966C6.

Expressioni

Gene expression databases

BgeeiWBGene00004419.

Interactioni

Subunit structurei

Interacts with cmd-1 in the presence of Ca2+.1 Publication

GO - Molecular functioni

  • calmodulin binding Source: WormBase

Protein-protein interaction databases

BioGridi42335. 4 interactors.
DIPiDIP-25472N.
MINTiMINT-1106781.
STRINGi6239.Y24D9A.4a.

Structurei

3D structure databases

ProteinModelPortaliQ966C6.
SMRiQ966C6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL8 family.Sequence analysis

Phylogenomic databases

eggNOGiKOG3166. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000004753.
HOGENOMiHOG000216644.
InParanoidiQ966C6.
KOiK02936.
OMAiRQRSILY.
OrthoDBiEOG091G0HPD.
PhylomeDBiQ966C6.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiView protein in InterPro
IPR029064. L30e-like.
IPR001921. Ribosomal_L7A/L8.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR004037. Ribosomal_L7Ae_CS.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00881. L7ARS6FAMILY.
PR00882. RIBOSOMALL7A.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiView protein in PROSITE
PS01082. RIBOSOMAL_L7AE. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform a1 Publication (identifier: Q966C6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPSKKVIKKK VAAVPAHIRA QTQVQKEVKN PLFEKRARNF NIGQDIQPKK
60 70 80 90 100
DVTRFVKWPK YIRLQRQSAI LQKRLKVPPT INQFRTALDS QSARQAFKLL
110 120 130 140 150
DKYRPESTEA KKNRLRARAE ARAAGKKEEV TKRPNTVRHG VNTITRLVET
160 170 180 190 200
RRAQLVLIAH DVNPLEIVLH LPALCRKYNV PYAIIKGKAS LGTVVRRKTT
210 220 230 240 250
AAVALVDVNP EDKSALNKLV ETVNNNFSER HEEIRKHWGG GVMSAKSDAK
260
KLKIERARAR DLGKL
Note: No experimental confirmation available.Curated
Length:265
Mass (Da):30,174
Last modified:January 23, 2007 - v3
Checksum:iAC44C4420295D932
GO
Isoform c1 Publication (identifier: Q966C6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     109-128: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:245
Mass (Da):27,939
Checksum:i80EE5089D0992E85
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_051845109 – 128Missing in isoform c. CuratedAdd BLAST20

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081479 Genomic DNA. Translation: CCD71898.1.
FO081479 Genomic DNA. Translation: CCD71899.1.
RefSeqiNP_741371.2. NM_171316.6. [Q966C6-1]
NP_741372.2. NM_171904.4. [Q966C6-2]
UniGeneiCel.9272.

Genome annotation databases

EnsemblMetazoaiY24D9A.4a; Y24D9A.4a; WBGene00004419. [Q966C6-1]
GeneIDi177203.
KEGGicel:CELE_Y24D9A.4.
UCSCiY24D9A.4a. c. elegans. [Q966C6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081479 Genomic DNA. Translation: CCD71898.1.
FO081479 Genomic DNA. Translation: CCD71899.1.
RefSeqiNP_741371.2. NM_171316.6. [Q966C6-1]
NP_741372.2. NM_171904.4. [Q966C6-2]
UniGeneiCel.9272.

3D structure databases

ProteinModelPortaliQ966C6.
SMRiQ966C6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi42335. 4 interactors.
DIPiDIP-25472N.
MINTiMINT-1106781.
STRINGi6239.Y24D9A.4a.

Proteomic databases

EPDiQ966C6.
PaxDbiQ966C6.
PeptideAtlasiQ966C6.
PRIDEiQ966C6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY24D9A.4a; Y24D9A.4a; WBGene00004419. [Q966C6-1]
GeneIDi177203.
KEGGicel:CELE_Y24D9A.4.
UCSCiY24D9A.4a. c. elegans. [Q966C6-1]

Organism-specific databases

CTDi177203.
WormBaseiY24D9A.4a; CE27398; WBGene00004419; rpl-7A.
Y24D9A.4c; CE30401; WBGene00004419; rpl-7A.

Phylogenomic databases

eggNOGiKOG3166. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000004753.
HOGENOMiHOG000216644.
InParanoidiQ966C6.
KOiK02936.
OMAiRQRSILY.
OrthoDBiEOG091G0HPD.
PhylomeDBiQ966C6.

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiPR:Q966C6.

Gene expression databases

BgeeiWBGene00004419.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiView protein in InterPro
IPR029064. L30e-like.
IPR001921. Ribosomal_L7A/L8.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR004037. Ribosomal_L7Ae_CS.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00881. L7ARS6FAMILY.
PR00882. RIBOSOMALL7A.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiView protein in PROSITE
PS01082. RIBOSOMAL_L7AE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRL7A_CAEEL
AccessioniPrimary (citable) accession number: Q966C6
Secondary accession number(s): Q8T875
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: January 23, 2007
Last modified: June 7, 2017
This is version 110 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.