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Q96554

- Q96554_9CHLO

UniProt

Q96554 - Q96554_9CHLO

Protein

Carbonic anhydrase

Gene
N/A
Organism
Coccomyxa sp. PA
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    H2CO3 = CO2 + H2O.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381Phosphate 2
    Metal bindingi47 – 471ZincImported
    Binding sitei49 – 491Phosphate 2
    Binding sitei88 – 881Phosphate 2
    Metal bindingi103 – 1031Zinc; via tele nitrogenImported
    Metal bindingi106 – 1061ZincImported

    GO - Molecular functioni

    1. carbonate dehydratase activity Source: UniProtKB-EC
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. carbon utilization Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Ligandi

    Metal-bindingImported, ZincUniRule annotationImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation)
    OrganismiCoccomyxa sp. PAImported
    Taxonomic identifieri41892 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeChlorophytaTrebouxiophyceaeCoccomyxaceaeCoccomyxa

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3UCJX-ray1.85A/B1-227[»]
    3UCKX-ray2.50A/B1-227[»]
    3UCMX-ray2.51A/B1-227[»]
    3UCNX-ray2.25A/B1-227[»]
    3UCOX-ray2.50A/B1-227[»]
    ProteinModelPortaliQ96554.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni103 – 1075Phosphate 2 binding

    Sequence similaritiesi

    Belongs to the beta-class carbonic anhydrase family.UniRule annotation

    Family and domain databases

    Gene3Di3.40.1050.10. 1 hit.
    InterProiIPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view]
    PANTHERiPTHR11002. PTHR11002. 1 hit.
    PfamiPF00484. Pro_CA. 1 hit.
    [Graphical view]
    SMARTiSM00947. Pro_CA. 1 hit.
    [Graphical view]
    SUPFAMiSSF53056. SSF53056. 1 hit.
    PROSITEiPS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96554-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAKDTADLS PLLEANRKWA DECAAKDSTY FSKVAGSQAP EYLYIGCADS    50
    RVSPAQLFNM APGEVFVQRN VGNLVSNKDL NCMSCLEYTV DHLKIKHILV 100
    CGHYNCGACK AGLVWHPKTA GVTNLWISDV REVRDKNAAK LHGLSADDAW 150
    DKMVELNVEA QVFNVCASPI VQAAWARGQP LSVHGIVYTP GTGLVKELIK 200
    PITGMEDAGA LLRADLKQHC FFSESLA 227
    Length:227
    Mass (Da):24,696
    Last modified:February 1, 1997 - v1
    Checksum:i97E3C72EBAB511DA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U49976 mRNA. Translation: AAC33484.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U49976 mRNA. Translation: AAC33484.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3UCJ X-ray 1.85 A/B 1-227 [» ]
    3UCK X-ray 2.50 A/B 1-227 [» ]
    3UCM X-ray 2.51 A/B 1-227 [» ]
    3UCN X-ray 2.25 A/B 1-227 [» ]
    3UCO X-ray 2.50 A/B 1-227 [» ]
    ProteinModelPortali Q96554.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.1050.10. 1 hit.
    InterProi IPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view ]
    PANTHERi PTHR11002. PTHR11002. 1 hit.
    Pfami PF00484. Pro_CA. 1 hit.
    [Graphical view ]
    SMARTi SM00947. Pro_CA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53056. SSF53056. 1 hit.
    PROSITEi PS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Intracellular beta-carbonic anhydrase of the unicellular green alga Coccomyxa. Cloning of the cdna and characterization of the functional enzyme overexpressed in Escherichia coli."
      Hiltonen T., Bjorkbacka H., Forsman C., Clarke A.K., Samuelsson G.
      Plant Physiol. 117:1341-1349(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: PAImported.
    2. "Structural studies of ?-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide."
      Huang S., Hainzl T., Grundstrom C., Forsman C., Samuelsson G., Sauer-Eriksson A.E.
      PLoS ONE 6:e28458-e28458(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ96554_9CHLO
    AccessioniPrimary (citable) accession number: Q96554
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3