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Q96540 (FRI1_BRANA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin-1, chloroplastic

EC=1.16.3.1
Gene names
Name:LSC30
OrganismBrassica napus (Rape)
Taxonomic identifier3708 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.

Subcellular location

Plastidchloroplast By similarity.

Sequence similarities

Belongs to the ferritin family.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

iron ion transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 4747Chloroplast Potential
Chain48 – 254207Ferritin-1, chloroplastic
PRO_0000008858

Regions

Domain87 – 240154Ferritin-like diiron
Region48 – 8639Extension peptide (EP)

Sites

Metal binding1041Iron 1 By similarity
Metal binding1391Iron 1 By similarity
Metal binding1391Iron 2 By similarity
Metal binding1421Iron 1 By similarity
Metal binding1881Iron 2 By similarity
Metal binding2221Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q96540 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 521CD0EC7B78C50D

FASTA25428,169
        10         20         30         40         50         60 
MASKALSSFT AKPAVSLLPH GVSSSASPSV MSLSFSRHTG GRGVVAASST VDTNNMPMTG 

        70         80         90        100        110        120 
VVFQPFEEVK KADLAIPITS NASLARQRYA DSSEAAINEQ INVEYNVSYV YHSMYAYFDR 

       130        140        150        160        170        180 
DNVALKGLAK FFKESSDEER EHAEKFMEYQ NQRGGRVTLH PIVSPISDFE HAEKGDALYA 

       190        200        210        220        230        240 
MELALSLEKL TNEKLLNLHR VASENNDPQL ADFVESEFLG EQIEAIKKIS DFITQLRMVG 

       250 
KGHGVWHFDQ MLLN 

« Hide

References

[1]"Leaf senescence in Brassica napus: cloning of senescence related genes by subtractive hybridisation."
Buchanan-Wollaston V., Ainsworth C.
Plant Mol. Biol. 33:821-834(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Falcon.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U68217 mRNA. Translation: AAB53099.1.
PIRT08593.

3D structure databases

ProteinModelPortalQ96540.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRI1_BRANA
AccessionPrimary (citable) accession number: Q96540
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: February 1, 1997
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families