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Reviewed, UniProtKB/Swiss-Prot Q96528 (CATA1_ARATH)

Last modified June 16, 2009. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Catalase-1
    EC=1.11.1.6
Gene names
Name: CAT1
Ordered Locus Names: At1g20630
ORF Names: F2D10.11, F5M15.31
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids IIBrassicalesBrassicaceaeArabidopsis

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Subunit structure

Homotetramer and heterotetramer. At least six or seven isozymes are produced from a mixture of 3 gene products.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the catalase family.

Sequence caution

The sequence AAF79625.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AAF80611.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 492492Catalase-1
PRO_0000084930

Sites

Active site651 By similarity
Active site1381 By similarity
Metal binding3481Iron (heme axial ligand) By similarity

Experimental info

Sequence conflict1031F → L in AAB07026. Ref.1
Sequence conflict3321G → F in AAB07026. Ref.1
Sequence conflict339 – 3402KL → NV in AAB07026. Ref.1
Sequence conflict4231G → R Ref.1
Sequence conflict4231G → R Ref.2
Sequence conflict4551S → W in AAB07026. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q96528-1 [UniParc].

Last modified July 11, 2002. Version 3.
Checksum: 271E55FF7D6910EB

FASTA49256,762
        10         20         30         40         50         60 
MDPYRVRPSS AHDSPFFTTN SGAPVWNNNS SLTVGTRGPI LLEDYHLLEK LANFDRERIP 

        70         80         90        100        110        120 
ERVVHARGAS AKGFFEVTHD ITQLTSADFL RGPGVQTPVI VRFSTVIHER GSPETLRDPR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNF PVFFVRDGMK FPDMVHALKP NPKSHIQENW RILDFFSHHP 

       190        200        210        220        230        240 
ESLHMFSFLF DDLGIPQDYR HMEGAGVNTY MLINKAGKAH YVKFHWKPTC GIKCLSDEEA 

       250        260        270        280        290        300 
IRVGGANHSH ATKDLYDSIA AGNYPQWNLF VQVMDPAHED KFDFDPLDVT KIWPEDILPL 

       310        320        330        340        350        360 
QPVGRLVLNK NIDNFFNENE QIAFCPALVV PGIHYSDDKL LQTRIFSYAD SQRHRLGPNY 

       370        380        390        400        410        420 
LQLPVNAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRLDPV RHAEKYPTTP IVCSGNREKC 

       430        440        450        460        470        480 
FIGKENNFKQ PGERYRSWDS DRQERFVKRF VEALSEPRVT HEIRSIWISY WSQADKSLGQ 

       490 
KLATRLNVRP NF 

« Hide

References

« Hide 'large scale' references
[1]"Catalase is encoded by a multigene family in Arabidopsis thaliana (L.) Heynh."
Frugoli J.A., Zhong H.H., Nuccio M.L., McCourt P., McPeek M.A., Thomas T.L., McClung C.R.
Plant Physiol. 112:327-336(1996) [PubMed: 8819328] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Landsberg erecta.
[2]"Intron loss and gain during evolution of the catalase gene family in angiosperms."
Frugoli J.A., McPeek M.A., Thomas T.L., McClung C.R.
Genetics 149:355-365(1998) [PubMed: 9584109] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Columbia.
[3]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed: 11130712] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Cross-references

Sequence databases

U43340 mRNA. Translation: AAB07026.1.
AF021937 Genomic DNA. Translation: AAC17731.1.
AC069251 Genomic DNA. Translation: AAF80611.1. Sequence problems.
AC027665 Genomic DNA. Translation: AAF79625.1. Sequence problems.
AY136424 mRNA. Translation: AAM97090.1.
BT010373 mRNA. Translation: AAQ56816.1.
IPIIPI00520908.
RefSeqNP_564121.1.
UniGeneAt.26213

3D structure databases

HSSPHSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBaseSearch...

Protein family/group databases

PeroxiBase5142. AtKat01.

Proteomic databases

PRIDEQ96528.
ProMEXQ96528.

Genome annotation databases

GeneID838652.
GenomeReviewsGene locus AT1G20630 in contig CT485782_GR.
KEGGath:AT1G20630.
NMPDRfig|3702.1.peg.2412.

Organism-specific databases

TAIRAt1g20630.

Phylogenomic databases

OMAQ96528. EPRVTHE.

Enzyme and pathway databases

BRENDA1.11.1.6. 302.

Gene expression databases

ArrayExpressQ96528.
GermOnlineAT1G20630. Arabidopsis thaliana.

Family and domain databases

InterProIPR002226. Catalase.
IPR010582. Catalase-rel_immune_responsive.
IPR011614. Catalase_N.
IPR018028. Catalase_rel_subgroup.
[Graphical view]
Gene3DG3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHERPTHR11465. Catalase. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PRINTSPR00067. CATALASE.
ProDomPD000510. Catalase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA1_ARATH
AccessionPrimary (citable) accession number: Q96528
Secondary accession number(s): O22529, Q9LDS9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 11, 2002
Last modified: June 16, 2009
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents