Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q96528

- CATA1_ARATH

UniProt

Q96528 - CATA1_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Catalase-1

Gene

CAT1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei65 – 651PROSITE-ProRule annotation
Active sitei138 – 1381PROSITE-ProRule annotation
Metal bindingi348 – 3481Iron (heme axial ligand)By similarity

GO - Molecular functioni

  1. catalase activity Source: TAIR
  2. cobalt ion binding Source: TAIR
  3. heme binding Source: InterPro

GO - Biological processi

  1. cellular response to nitrogen starvation Source: TAIR
  2. cellular response to phosphate starvation Source: TAIR
  3. cellular response to sulfate starvation Source: TAIR
  4. hydrogen peroxide catabolic process Source: TAIR
  5. response to abscisic acid Source: TAIR
  6. response to cadmium ion Source: TAIR
  7. response to hydrogen peroxide Source: TAIR
  8. response to light stimulus Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_180046. Detoxification of Reactive Oxygen Species.
REACT_219858. Purine catabolism.

Protein family/group databases

PeroxiBasei5142. AtKat01.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-1 (EC:1.11.1.6)
Gene namesi
Name:CAT1
Ordered Locus Names:At1g20630
ORF Names:F2D10.11, F5M15.31
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G20630.

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cell wall Source: TAIR
  2. chloroplast envelope Source: TAIR
  3. cytosolic ribosome Source: TAIR
  4. mitochondrion Source: TAIR
  5. peroxisome Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 492492Catalase-1PRO_0000084930Add
BLAST

Proteomic databases

PaxDbiQ96528.
PRIDEiQ96528.

Expressioni

Inductioni

By hydrogen peroxide. By abscisic acid (ABA), drought, and salt stress through the MKK1-MPK6 mediation.2 Publications

Gene expression databases

ExpressionAtlasiQ96528. baseline and differential.
GenevestigatoriQ96528.

Interactioni

Subunit structurei

Homotetramer and heterotetramer. At least six or seven isozymes are produced from a mixture of 3 gene products.

Protein-protein interaction databases

BioGridi23891. 6 interactions.
IntActiQ96528. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ96528.
SMRiQ96528. Positions 10-483.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.Curated

Phylogenomic databases

eggNOGiCOG0753.
HOGENOMiHOG000087852.
KOiK03781.
OMAiLIHAQKR.
PhylomeDBiQ96528.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96528-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDPYRVRPSS AHDSPFFTTN SGAPVWNNNS SLTVGTRGPI LLEDYHLLEK
60 70 80 90 100
LANFDRERIP ERVVHARGAS AKGFFEVTHD ITQLTSADFL RGPGVQTPVI
110 120 130 140 150
VRFSTVIHER GSPETLRDPR GFAVKFYTRE GNFDLVGNNF PVFFVRDGMK
160 170 180 190 200
FPDMVHALKP NPKSHIQENW RILDFFSHHP ESLHMFSFLF DDLGIPQDYR
210 220 230 240 250
HMEGAGVNTY MLINKAGKAH YVKFHWKPTC GIKCLSDEEA IRVGGANHSH
260 270 280 290 300
ATKDLYDSIA AGNYPQWNLF VQVMDPAHED KFDFDPLDVT KIWPEDILPL
310 320 330 340 350
QPVGRLVLNK NIDNFFNENE QIAFCPALVV PGIHYSDDKL LQTRIFSYAD
360 370 380 390 400
SQRHRLGPNY LQLPVNAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRLDPV
410 420 430 440 450
RHAEKYPTTP IVCSGNREKC FIGKENNFKQ PGERYRSWDS DRQERFVKRF
460 470 480 490
VEALSEPRVT HEIRSIWISY WSQADKSLGQ KLATRLNVRP NF
Length:492
Mass (Da):56,762
Last modified:July 11, 2002 - v3
Checksum:i271E55FF7D6910EB
GO

Sequence cautioni

The sequence AAF79625.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence AAF80611.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti103 – 1031F → L in AAB07026. (PubMed:8819328)Curated
Sequence conflicti332 – 3321G → F in AAB07026. (PubMed:8819328)Curated
Sequence conflicti339 – 3402KL → NV in AAB07026. (PubMed:8819328)Curated
Sequence conflicti423 – 4231G → R in AAB07026. (PubMed:8819328)Curated
Sequence conflicti423 – 4231G → R in AAC17731. (PubMed:9584109)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43340 mRNA. Translation: AAB07026.1.
AF021937 Genomic DNA. Translation: AAC17731.1.
AC027665 Genomic DNA. Translation: AAF79625.1. Sequence problems.
AC069251 Genomic DNA. Translation: AAF80611.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE29998.1.
AY136424 mRNA. Translation: AAM97090.1.
BT010373 mRNA. Translation: AAQ56816.1.
RefSeqiNP_564121.1. NM_101914.3.
UniGeneiAt.26213.

Genome annotation databases

EnsemblPlantsiAT1G20630.1; AT1G20630.1; AT1G20630.
GeneIDi838652.
KEGGiath:AT1G20630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43340 mRNA. Translation: AAB07026.1 .
AF021937 Genomic DNA. Translation: AAC17731.1 .
AC027665 Genomic DNA. Translation: AAF79625.1 . Sequence problems.
AC069251 Genomic DNA. Translation: AAF80611.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE29998.1 .
AY136424 mRNA. Translation: AAM97090.1 .
BT010373 mRNA. Translation: AAQ56816.1 .
RefSeqi NP_564121.1. NM_101914.3.
UniGenei At.26213.

3D structure databases

ProteinModelPortali Q96528.
SMRi Q96528. Positions 10-483.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 23891. 6 interactions.
IntActi Q96528. 2 interactions.

Protein family/group databases

PeroxiBasei 5142. AtKat01.

Proteomic databases

PaxDbi Q96528.
PRIDEi Q96528.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G20630.1 ; AT1G20630.1 ; AT1G20630 .
GeneIDi 838652.
KEGGi ath:AT1G20630.

Organism-specific databases

TAIRi AT1G20630.

Phylogenomic databases

eggNOGi COG0753.
HOGENOMi HOG000087852.
KOi K03781.
OMAi LIHAQKR.
PhylomeDBi Q96528.

Enzyme and pathway databases

Reactomei REACT_180046. Detoxification of Reactive Oxygen Species.
REACT_219858. Purine catabolism.

Gene expression databases

ExpressionAtlasi Q96528. baseline and differential.
Genevestigatori Q96528.

Family and domain databases

Gene3Di 2.40.180.10. 1 hit.
InterProi IPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view ]
PANTHERi PTHR11465. PTHR11465. 1 hit.
Pfami PF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view ]
PIRSFi PIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSi PR00067. CATALASE.
SMARTi SM01060. Catalase. 1 hit.
[Graphical view ]
SUPFAMi SSF56634. SSF56634. 1 hit.
PROSITEi PS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Catalase is encoded by a multigene family in Arabidopsis thaliana (L.) Heynh."
    Frugoli J.A., Zhong H.H., Nuccio M.L., McCourt P., McPeek M.A., Thomas T.L., McClung C.R.
    Plant Physiol. 112:327-336(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Landsberg erecta.
  2. "Intron loss and gain during evolution of the catalase gene family in angiosperms."
    Frugoli J.A., McPeek M.A., Thomas T.L., McClung C.R.
    Genetics 149:355-365(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Columbia.
  3. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  4. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  5. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "AtMEK1 mediates stress-induced gene expression of CAT1 catalase by triggering H2O2 production in Arabidopsis."
    Xing Y., Jia W., Zhang J.
    J. Exp. Bot. 58:2969-2981(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  7. "AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis."
    Xing Y., Jia W., Zhang J.
    Plant J. 54:440-451(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiCATA1_ARATH
AccessioniPrimary (citable) accession number: Q96528
Secondary accession number(s): O22529, Q9LDS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 11, 2002
Last modified: November 26, 2014
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3