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Q96519 (PER11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peroxidase 11

Short name=Atperox P11
EC=1.11.1.7
Alternative name(s):
ATP23a/ATP23b
Gene names
Name:PER11
Synonyms:P11
Ordered Locus Names:At1g68850
ORF Names:T6L1.4, F14K14.4
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Catalytic activity

2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Binds 2 calcium ions per subunit By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Expressed in roots and stems.

Induction

Expressed under a diurnal rhythm. Ref.5

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Sequence similarities

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Ontologies

Keywords
   Biological processBiological rhythms
Hydrogen peroxide
   Cellular componentSecreted
   DomainSignal
   LigandCalcium
Heme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processhydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

rhythmic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionheme binding

Inferred from electronic annotation. Source: InterPro

peroxidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 336316Peroxidase 11
PRO_0000023677

Sites

Active site701Proton acceptor By similarity
Metal binding711Calcium 1 By similarity
Metal binding741Calcium 1; via carbonyl oxygen By similarity
Metal binding761Calcium 1; via carbonyl oxygen By similarity
Metal binding781Calcium 1 By similarity
Metal binding801Calcium 1 By similarity
Metal binding1971Iron (heme axial ligand) By similarity
Metal binding1981Calcium 2 By similarity
Metal binding2511Calcium 2 By similarity
Metal binding2541Calcium 2 By similarity
Metal binding2591Calcium 2 By similarity
Binding site1671Substrate; via carbonyl oxygen By similarity
Site661Transition state stabilizer By similarity

Amino acid modifications

Glycosylation2461N-linked (GlcNAc...) Potential
Disulfide bond39 ↔ 119 By similarity
Disulfide bond72 ↔ 77 By similarity
Disulfide bond125 ↔ 331 By similarity
Disulfide bond204 ↔ 236 By similarity

Experimental info

Sequence conflict192 – 1943ALI → YLL in CAA72485. Ref.1
Sequence conflict2181T → M in CAA72485. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q96519 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 846D69A84530900B

FASTA33637,313
        10         20         30         40         50         60 
MMRLLFVFFM VHTIFIPCFS FDTPGKDLPL TLDYYKSTCP TVFDVIKKEM ECIVKEDPRN 

        70         80         90        100        110        120 
AAIIIRLHFH DCFVQGCDGS VLLDETETLQ GEKKASPNIN SLKGYKIVDR IKNIIESECP 

       130        140        150        160        170        180 
GVVSCADLLT IGARDATILV GGPYWDVPVG RKDSKTASYE LATTNLPTPE EGLISIIAKF 

       190        200        210        220        230        240 
YSQGLSVEDM VALIGAHTIG KAQCRNFRSR IYGDFQVTSA LNPVSETYLA SLREICPASS 

       250        260        270        280        290        300 
GEGDSNVTAI DNVTPNLFDN SIYHTLLRGE GLLNSDQEMY TSLFGIQTRR IVSKYAEDPV 

       310        320        330 
AFFEQFSKSM VKMGNILNSE SLADGEVRRN CRFVNT 

« Hide

References

« Hide 'large scale' references
[1]"From expressed sequence tags to structure, function, evolution and expression of 28 ER-targeted Arabidopsis peroxidases."
Welinder K.G., Jespersen H.M., Kjaersgaard I.V.H., Justesen A.F., Oestergaard L., Abelskov A.K., Jensen R.B., Hansen L.N., Rasmussen S.K.
Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed: 11130712] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Computational analyses and annotations of the Arabidopsis peroxidase gene family."
Oestergaard L., Pedersen A.G., Jespersen H.M., Brunak S., Welinder K.G.
FEBS Lett. 433:98-102(1998) [PubMed: 9738941] [Abstract]
Cited for: CHARACTERIZATION.
Strain: cv. Columbia.
[5]"Microarray analysis of diurnal and circadian-regulated genes in Arabidopsis."
Schaffer R., Landgraf J., Accerbi M., Simon V., Larson M., Wisman E.
Plant Cell 13:113-123(2001) [PubMed: 11158533] [Abstract]
Cited for: INDUCTION.
Strain: cv. Columbia.
[6]"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana."
Tognolli M., Penel C., Greppin H., Simon P.
Gene 288:129-138(2002) [PubMed: 12034502] [Abstract]
Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y08782 mRNA. Translation: CAA70035.1.
Y11789 mRNA. Translation: CAA72485.1.
AC011665 Genomic DNA. Translation: AAG51588.1.
AC011914 Genomic DNA. Translation: AAG52033.1.
CP002684 Genomic DNA. Translation: AEE34850.1.
IPIIPI00535181.
PIRC96713.
RefSeqNP_564948.1. NM_105559.3.
UniGeneAt.87.

3D structure databases

ProteinModelPortalQ96519.
SMRQ96519. Positions 29-336.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ96519.

Protein family/group databases

PeroxiBase92. AtPrx11.

Proteomic databases

PRIDEQ96519.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G68850.1; AT1G68850.1; AT1G68850.
GeneID843218.
GenomeReviewsGene locus AT1G68850 in contig CT485782_GR.
KEGGath:AT1G68850.
NMPDRfig|3702.1.peg.6343.

Organism-specific databases

GeneFarm1473. 61.
TAIRAt1g68850.

Phylogenomic databases

GeneTreeEPGT00070000027987.
HOGENOMHBG597790.
InParanoidQ96519.
OMAKQFSDSM.
PhylomeDBQ96519.
ProtClustDBCLSN2689092.

Gene expression databases

GenevestigatorQ96519.
GermOnlineAT1G68850. Arabidopsis thaliana.

Family and domain databases

InterProIPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR000823. Peroxidase_pln.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
KOK00430.
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00458. PEROXIDASE.
PR00461. PLPEROXIDASE.
SUPFAMSSF48113. Peroxidase_super. 1 hit.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePER11_ARATH
AccessionPrimary (citable) accession number: Q96519
Secondary accession number(s): P93723
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: February 1, 1997
Last modified: December 14, 2011
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families