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Protein

Peroxidase 9

Gene

PER9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Catalytic activityi

2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.

Cofactori

Protein has several cofactor binding sites:
  • heme bPROSITE-ProRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.PROSITE-ProRule annotation
  • Ca2+PROSITE-ProRule annotationNote: Binds 2 calcium ions per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei81Transition state stabilizerPROSITE-ProRule annotation1
Active sitei85Proton acceptorPROSITE-ProRule annotation1
Metal bindingi86Calcium 1PROSITE-ProRule annotation1
Metal bindingi89Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi91Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi93Calcium 1PROSITE-ProRule annotation1
Metal bindingi95Calcium 1PROSITE-ProRule annotation1
Binding sitei182Substrate; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi212Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi213Calcium 2PROSITE-ProRule annotation1
Metal bindingi264Calcium 2PROSITE-ProRule annotation1
Metal bindingi267Calcium 2PROSITE-ProRule annotation1
Metal bindingi272Calcium 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Calcium, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G44970-MONOMER.

Protein family/group databases

PeroxiBasei85. AtPrx09.

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxidase 9 (EC:1.11.1.7)
Short name:
Atperox P9
Alternative name(s):
ATP18a
Gene namesi
Name:PER9
Synonyms:P9
Ordered Locus Names:At1g44970
ORF Names:F27F5.6, T22C22.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G44970.

Subcellular locationi

  • Secreted PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000002367524 – 346Peroxidase 9Add BLAST323

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi54 ↔ 134PROSITE-ProRule annotation
Disulfide bondi87 ↔ 92PROSITE-ProRule annotation
Disulfide bondi140 ↔ 342PROSITE-ProRule annotation
Glycosylationi185N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi219 ↔ 251PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ96512.

Expressioni

Gene expression databases

ExpressionAtlasiQ96512. baseline and differential.
GenevisibleiQ96512. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G44970.1.

Structurei

3D structure databases

ProteinModelPortaliQ96512.
SMRiQ96512.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IIDC. Eukaryota.
ENOG410YFB5. LUCA.
HOGENOMiHOG000237557.
InParanoidiQ96512.
KOiK00430.
OMAiRFDNTYF.
OrthoDBiEOG09360EN5.
PhylomeDBiQ96512.

Family and domain databases

CDDicd00693. secretory_peroxidase. 1 hit.
InterProiIPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR000823. Peroxidase_pln.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
IPR033905. Secretory_peroxidase.
[Graphical view]
PfamiPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00458. PEROXIDASE.
PR00461. PLPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q96512-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAISKLIPTL VLFVLFSFDV SVAHPGLGFG WGSNSPIGGS FYSNLYPQFY
60 70 80 90 100
QFSCPQADEI VMTVLEKAIA KEPRMAASLL RLHFHDCFVQ GCDASILLDD
110 120 130 140 150
SATIRSEKNA GPNKNSVRGF QVIDEIKAKL EQACPQTVSC ADILALAARG
160 170 180 190 200
STILSGGPSW ELPLGRRDSR TASLNGANTN IPAPNSTIQN LLTMFQRKGL
210 220 230 240 250
NEEDLVSLSG GHTIGVARCT TFKQRLYNQN GNNQPDETLE RSYYYGLRSI
260 270 280 290 300
CPPTGGDNNI SPLDLASPAR FDNTYFKLLL WGKGLLTSDE VLLTGNVGKT
310 320 330 340
GALVKAYAED ERLFFQQFAK SMVNMGNIQP LTGFNGEIRK SCHVIN
Length:346
Mass (Da):37,741
Last modified:February 1, 1997 - v1
Checksum:i47EFD6297469A065
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti269A → S in AAM63684 (Ref. 5) Curated1
Sequence conflicti290E → Q in AAM63684 (Ref. 5) Curated1
Sequence conflicti302A → S in AAM63684 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98804 mRNA. Translation: CAA67336.1.
AC007915 Genomic DNA. Translation: AAF69153.1.
AC020576 Genomic DNA. Translation: AAF78280.1.
CP002684 Genomic DNA. Translation: AEE32069.1.
BT008612 mRNA. Translation: AAP40436.1.
AY086626 mRNA. Translation: AAM63684.1.
RefSeqiNP_175117.1. NM_103577.4.
UniGeneiAt.140.

Genome annotation databases

EnsemblPlantsiAT1G44970.1; AT1G44970.1; AT1G44970.
GeneIDi841062.
GrameneiAT1G44970.1; AT1G44970.1; AT1G44970.
KEGGiath:AT1G44970.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98804 mRNA. Translation: CAA67336.1.
AC007915 Genomic DNA. Translation: AAF69153.1.
AC020576 Genomic DNA. Translation: AAF78280.1.
CP002684 Genomic DNA. Translation: AEE32069.1.
BT008612 mRNA. Translation: AAP40436.1.
AY086626 mRNA. Translation: AAM63684.1.
RefSeqiNP_175117.1. NM_103577.4.
UniGeneiAt.140.

3D structure databases

ProteinModelPortaliQ96512.
SMRiQ96512.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G44970.1.

Protein family/group databases

PeroxiBasei85. AtPrx09.

Proteomic databases

PaxDbiQ96512.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G44970.1; AT1G44970.1; AT1G44970.
GeneIDi841062.
GrameneiAT1G44970.1; AT1G44970.1; AT1G44970.
KEGGiath:AT1G44970.

Organism-specific databases

TAIRiAT1G44970.

Phylogenomic databases

eggNOGiENOG410IIDC. Eukaryota.
ENOG410YFB5. LUCA.
HOGENOMiHOG000237557.
InParanoidiQ96512.
KOiK00430.
OMAiRFDNTYF.
OrthoDBiEOG09360EN5.
PhylomeDBiQ96512.

Enzyme and pathway databases

BioCyciARA:AT1G44970-MONOMER.

Miscellaneous databases

PROiQ96512.

Gene expression databases

ExpressionAtlasiQ96512. baseline and differential.
GenevisibleiQ96512. AT.

Family and domain databases

CDDicd00693. secretory_peroxidase. 1 hit.
InterProiIPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR000823. Peroxidase_pln.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
IPR033905. Secretory_peroxidase.
[Graphical view]
PfamiPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00458. PEROXIDASE.
PR00461. PLPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPER9_ARATH
AccessioniPrimary (citable) accession number: Q96512
Secondary accession number(s): Q9LPD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.