Unreviewed, UniProtKB/TrEMBL Q964Q0 (Q964Q0_IXOSC)

Names and origin

Protein names	Submitted name:     Ixolaris EMBL AAK83022.1
Organism	Ixodes scapularis (Black-legged tick) (Deer tick) EMBL AAK83022.1
Taxonomic identifier	6945 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Ixodinae › Ixodes

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 BPTI/Kunitz inhibitor domain. RuleBase RU000413V1

Ontologies

Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
F10	O88947	1	EBI-1646347,EBI-1646313	From a different organism.
F10	P00742	1	EBI-1646347,EBI-719750	From a different organism.

Sequences

	Sequence		Length	Mass (Da)
	Q964Q0-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: CD37AA8EEDDB70F4	FASTA	165	18,403
	10 20 30 40 50 60 MRAVSCFLYY GVAWIALGSW GASSSAERVS EMDIYEFESW VSCLDPEQVT CESQEGTHAS 70 80 90 100 110 120 YNRKTGQCEE QKGTECGGGE NHFETLLKCN ESCNDAPKPP CSLEVDYGVG RANIPRWYYD 130 140 150 160 TNNATCEMFT YGGITGNKNN FESEEECKET CKGFSLLKKV NVTIN

References

[1]

"Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex." Francischetti I.M., Valenzuela J.G., Andersen J.F., Mather T.N., Ribeiro J.M. Blood 99:3602-3612(2002) [PubMed: 11986214] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF286029 mRNA. Translation: AAK83022.1.
3D structure databases
HSSP	HSSP built from PDB template 1KTH based on UniProtKB P12111.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q964Q0. 2 interactions.
Protein family/group databases
MEROPS	I02.025.
Family and domain databases
InterPro	IPR002223. Prot_inh_Kunz-m. [Graphical view]
Gene3D	G3DSA:4.10.410.10. Prot_inh_Kunz-m. 1 hit.
Pfam	PF00014. Kunitz_BPTI. 2 hits. [Graphical view]
ProDom	PD000222. Prot_Inh_Kunz-m. 2 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00131. KU. 1 hit. [Graphical view]
PROSITE	PS50279. BPTI_KUNITZ_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q964Q0_IXOSC

Accession

Primary (citable) accession number: Q964Q0

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	February 10, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)