Reviewed,
UniProtKB/Swiss-Prot Q964D8 (BUP1_DICDI)
Last modified
June 16, 2009.
Version 36.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Beta-ureidopropionase EC=3.5.1.6 Alternative name(s): Beta-alanine synthase N-carbamoyl-beta-alanine amidohydrolase | ||||||
| Gene names |
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| Organism | Dictyostelium discoideum (Slime mold) [Complete proteome] | ||||||
| Taxonomic identifier | 44689 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 391 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Converts N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to, respectively, beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide. |
| Catalytic activity | N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3. Ref.1 |
| Pathway | |
| Sequence similarities | Belongs to the CN hydrolase family. BUP subfamily. Contains 1 CN hydrolase domain. |
| Caution | Lacks the zinc-binding sites found in mammalian orthologs. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | beta-ureidopropionase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| AF333186 mRNA. Translation: AAK60519.1. AC116957 Genomic DNA. Translation: AAO52475.1. AAFI02000012 Genomic DNA. Translation: EAL69954.1. | |
| RefSeq | XP_644181.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3395444. |
| KEGG | ddi:DDB_0185221. |
Organism-specific databases | |
| dictyBase | DDB_G0274123. pyd3. |
Phylogenomic databases | |
| OMA | Q964D8. AIANSYF. |
Enzyme and pathway databases | |
| BRENDA | 3.5.1.6. 424. |
Family and domain databases | |
| InterPro | IPR003010. Ntlse/CNhydtse. [Graphical view] |
| Gene3D | G3DSA:3.60.110.10. Ntlse/CNhydtse. 1 hit. |
| Pfam | PF00795. CN_hydrolase. 1 hit. [Graphical view] |
| PROSITE | PS50263. CN_HYDROLASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BUP1_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q964D8 Secondary accession number(s): Q554Z2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


