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Protein

Floral homeotic protein APETALA 1-2

Gene

2AP1

Organism
Brassica oleracea var. italica (Broccoli)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Transcription factor that promotes early floral meristem identity in synergy with LEAFY. Displays a redundant function with CAULIFLOWER in the up-regulation of LEAFY. Required subsequently for the transition of an inflorescence meristem into a floral meristem, and for the normal development of sepals and petals in flowers. Regulates positively B class homeotic proteins (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator, Developmental protein

Keywords - Biological processi

Differentiation, Flowering, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Floral homeotic protein APETALA 1-2
Short name:
Boi2AP1
Alternative name(s):
Agamous-like MADS-box protein 2AP1
Gene namesi
Name:2AP1
OrganismiBrassica oleracea var. italica (Broccoli)
Taxonomic identifieri36774 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Floral homeotic protein APETALA 1-2PRO_0000417136Add
BLAST

Interactioni

Subunit structurei

Homodimer capable of binding to CArG-box sequences.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ96356.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6161MADS-boxPROSITE-ProRule annotationAdd
BLAST
Domaini88 – 17891K-boxPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi196 – 2016Poly-Pro

Sequence similaritiesi

Contains 1 K-box domain.PROSITE-ProRule annotation
Contains 1 MADS-box domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Family and domain databases

InterProiIPR002487. TF_Kbox.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF01486. K-box. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS51297. K_BOX. 1 hit.
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96356-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRGRVQLKR IENKINRQVT FSKRRAGLMK KAHEISVLCD AEVALVVFSH
60 70 80 90 100
KGKLFEYSTD SCMEKILERY ERYSYAERQL IAPESDSNTN WSMEYNRLKA
110 120 130 140 150
KIELLERNQR HYLGEDLQAM SPKELQNLEQ QLDTALKHIR SRKNQLMYDS
160 170 180 190 200
INELQRKEKA IQEQNSMLSK QIKERENVLR AQQEQWDEQN HGHNMPPPPP
210 220 230 240 250
PQQHQIQHPY MLSHQPSPFL NMGGLYQEED QMAMRRNDLD LSLEPVYNCN

LGCFAA
Length:256
Mass (Da):30,171
Last modified:February 1, 1997 - v1
Checksum:i71936E3479B4DB48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67452 mRNA. Translation: AAB08876.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U67452 mRNA. Translation: AAB08876.1.

3D structure databases

ProteinModelPortaliQ96356.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR002487. TF_Kbox.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF01486. K-box. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS51297. K_BOX. 1 hit.
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Floral homeotic gene expression defines developmental arrest stages in Brassica oleracea L. vars. botrytis and italica."
    Carr S.M., Irish V.F.
    Planta 201:179-188(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Flower.

Entry informationi

Entry namei2AP1_BRAOT
AccessioniPrimary (citable) accession number: Q96356
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2012
Last sequence update: February 1, 1997
Last modified: October 14, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.