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Protein

Glutathione S-transferase F11

Gene

GSTF11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • response to oxidative stress Source: TAIR
  • response to toxic substance Source: UniProtKB-KW
  • toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Enzyme and pathway databases

BioCyciARA:AT3G03190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase F11 (EC:2.5.1.18)
Short name:
AtGSTF11
Alternative name(s):
AtGSTF6
GST class-phi
GST class-phi member 11
Gene namesi
Name:GSTF11
Synonyms:GSTF6
Ordered Locus Names:At3g03190
ORF Names:T17B22.12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G03190.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001858512 – 214Glutathione S-transferase F11Add BLAST213

Proteomic databases

PaxDbiQ96324.
PRIDEiQ96324.

Expressioni

Gene expression databases

GenevisibleiQ96324. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G03190.1.

Structurei

3D structure databases

ProteinModelPortaliQ96324.
SMRiQ96324.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 82GST N-terminalAdd BLAST81
Domaini89 – 214GST C-terminalAdd BLAST126

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni11 – 12Glutathione bindingBy similarity2
Regioni40 – 41Glutathione bindingBy similarity2
Regioni53 – 54Glutathione bindingBy similarity2
Regioni66 – 67Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
COG0625. LUCA.
HOGENOMiHOG000125746.
InParanoidiQ96324.
KOiK00799.
OMAiMRYIMNE.
OrthoDBiEOG09360M18.
PhylomeDBiQ96324.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q96324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVKVYGQIK AANPQRVLLC FLEKDIEFEV IHVDLDKLEQ KKPQHLLRQP
60 70 80 90 100
FGQVPAIEDG YLKLFESRAI ARYYATKYAD QGTDLLGKTL EGRAIVDQWV
110 120 130 140 150
EVENNYFYAV ALPLVMNVVF KPKSGKPCDV ALVEELKVKF DKVLDVYENR
160 170 180 190 200
LATNRYLGGD EFTLADLSHM PGMRYIMNET SLSGLVTSRE NLNRWWNEIS
210
ARPAWKKLME LAAY
Length:214
Mass (Da):24,637
Last modified:February 1, 1997 - v1
Checksum:i24B58B67A5672E91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70672 mRNA. Translation: AAB09584.1.
AC012328 Genomic DNA. Translation: AAF26107.1.
CP002686 Genomic DNA. Translation: AEE73911.1.
AY099776 mRNA. Translation: AAM20627.1.
AY128877 mRNA. Translation: AAM91277.1.
RefSeqiNP_186969.1. NM_111189.3.
UniGeneiAt.24063.

Genome annotation databases

EnsemblPlantsiAT3G03190.1; AT3G03190.1; AT3G03190.
GeneIDi821227.
GrameneiAT3G03190.1; AT3G03190.1; AT3G03190.
KEGGiath:AT3G03190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70672 mRNA. Translation: AAB09584.1.
AC012328 Genomic DNA. Translation: AAF26107.1.
CP002686 Genomic DNA. Translation: AEE73911.1.
AY099776 mRNA. Translation: AAM20627.1.
AY128877 mRNA. Translation: AAM91277.1.
RefSeqiNP_186969.1. NM_111189.3.
UniGeneiAt.24063.

3D structure databases

ProteinModelPortaliQ96324.
SMRiQ96324.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G03190.1.

Proteomic databases

PaxDbiQ96324.
PRIDEiQ96324.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G03190.1; AT3G03190.1; AT3G03190.
GeneIDi821227.
GrameneiAT3G03190.1; AT3G03190.1; AT3G03190.
KEGGiath:AT3G03190.

Organism-specific databases

TAIRiAT3G03190.

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
COG0625. LUCA.
HOGENOMiHOG000125746.
InParanoidiQ96324.
KOiK00799.
OMAiMRYIMNE.
OrthoDBiEOG09360M18.
PhylomeDBiQ96324.

Enzyme and pathway databases

BioCyciARA:AT3G03190-MONOMER.

Miscellaneous databases

PROiQ96324.

Gene expression databases

GenevisibleiQ96324. AT.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSTFB_ARATH
AccessioniPrimary (citable) accession number: Q96324
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.