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Protein

Inorganic phosphate transporter 1-4

Gene

PHT1-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

High-affinity transporter for external inorganic phosphate. Acts as a H+:phosphate symporter in both low- and high-Pi conditions. Confers sensitivity to arsenate.3 Publications

GO - Molecular functioni

GO - Biological processi

  • phosphate ion transport Source: UniProtKB-KW
  • response to abscisic acid Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Symport, Transport

Enzyme and pathway databases

BioCyciARA:GQT-2244-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic phosphate transporter 1-4
Short name:
AtPht1;4
Alternative name(s):
H(+)/Pi cotransporter
Gene namesi
Name:PHT1-4
Synonyms:PHT4, PT2
Ordered Locus Names:At2g38940
ORF Names:T7F6.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G38940.

Subcellular locationi

  • Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 70ExtracellularSequence analysisAdd BLAST25
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 99CytoplasmicSequence analysis8
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Topological domaini121 – 131ExtracellularSequence analysisAdd BLAST11
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Topological domaini153 – 161CytoplasmicSequence analysis9
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 211ExtracellularSequence analysisAdd BLAST29
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21
Topological domaini233 – 293CytoplasmicSequence analysisAdd BLAST61
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21
Topological domaini315 – 349ExtracellularSequence analysisAdd BLAST35
Transmembranei350 – 370HelicalSequence analysisAdd BLAST21
Topological domaini371 – 372CytoplasmicSequence analysis2
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Topological domaini394 – 403ExtracellularSequence analysis10
Transmembranei404 – 424HelicalSequence analysisAdd BLAST21
Topological domaini425 – 442CytoplasmicSequence analysisAdd BLAST18
Transmembranei443 – 463HelicalSequence analysisAdd BLAST21
Topological domaini464 – 484ExtracellularSequence analysisAdd BLAST21
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21
Topological domaini506 – 534CytoplasmicSequence analysisAdd BLAST29

GO - Cellular componenti

  • Golgi apparatus Source: TAIR
  • integral component of plasma membrane Source: GO_Central
  • membrane Source: TAIR
  • nucleus Source: TAIR
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
  • vacuole Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504711 – 534Inorganic phosphate transporter 1-4Add BLAST534

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei524PhosphoserineCombined sources1
Modified residuei528PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ96303.
PRIDEiQ96303.

PTM databases

iPTMnetiQ96303.

Expressioni

Tissue specificityi

Mostly expressed in roots, in tissues connecting the lateral roots to the primary root. Also present in flowers, in senescing anther filaments and in the abscission zone at the base of siliques. Expressed in hydathodes and axillary buds, and in some senescing leaves. After Pi starvation, localized in all cells of undifferentiated root segments, including root tips and root hairs, and in the epidermis, cortex and stellar regions of mature root segments.5 Publications

Inductioni

In roots by phosphate starvation. Repressed by the Pi analog phosphite (Phi).6 Publications

Gene expression databases

GenevisibleiQ96303. AT.

Interactioni

Protein-protein interaction databases

BioGridi3818. 2 interactors.
STRINGi3702.AT2G38940.1.

Structurei

3D structure databases

ProteinModelPortaliQ96303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96303.
KOiK08176.
OMAiFFAPMIK.
OrthoDBiEOG093607P7.
PhylomeDBiQ96303.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96303-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAREQLQVLN ALDVAKTQWY HFTAIIIAGM GFFTDAYDLF CISLVTKLLG
60 70 80 90 100
RIYYHVEGAQ KPGTLPPNVA AAVNGVAFCG TLAGQLFFGW LGDKLGRKKV
110 120 130 140 150
YGMTLMVMVL CSIASGLSFG HEPKAVMATL CFFRFWLGFG IGGDYPLSAT
160 170 180 190 200
IMSEYANKKT RGAFVSAVFA MQGFGIMAGG IFAIIISSAF EAKFPSPAYA
210 220 230 240 250
DDALGSTIPQ ADLVWRIILM AGAIPAAMTY YSRSKMPETA RYTALVAKDA
260 270 280 290 300
KQAASDMSKV LQVEIEPEQQ KLEEISKEKS KAFGLFSKEF MSRHGLHLLG
310 320 330 340 350
TTSTWFLLDI AFYSQNLFQK DIFSAIGWIP PAQSMNAIQE VFKIARAQTL
360 370 380 390 400
IALCSTVPGY WFTVAFIDVI GRFAIQMMGF FFMTVFMFAL AIPYNHWTHK
410 420 430 440 450
ENRIGFVIMY SLTFFFANFG PNATTFVVPA EIFPARFRST CHGISAASGK
460 470 480 490 500
LGAMVGAFGF LYLAQNPDKD KTDAGYPPGI GVRNSLIVLG VVNFLGILFT
510 520 530
FLVPESKGKS LEEMSGENED NENSNNDSRT VPIV
Length:534
Mass (Da):58,599
Last modified:February 1, 1997 - v1
Checksum:i8186DBBBCBC8379E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62331 mRNA. Translation: AAB17266.1.
AF022872 Genomic DNA. Translation: AAB88291.1.
AB016166 Genomic DNA. Translation: BAA34398.1.
AC005770 Genomic DNA. Translation: AAC79607.1.
CP002685 Genomic DNA. Translation: AEC09615.1.
PIRiC84811.
RefSeqiNP_181428.1. NM_129452.4.
UniGeneiAt.255.
At.67089.

Genome annotation databases

EnsemblPlantsiAT2G38940.1; AT2G38940.1; AT2G38940.
GeneIDi818479.
GrameneiAT2G38940.1; AT2G38940.1; AT2G38940.
KEGGiath:AT2G38940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62331 mRNA. Translation: AAB17266.1.
AF022872 Genomic DNA. Translation: AAB88291.1.
AB016166 Genomic DNA. Translation: BAA34398.1.
AC005770 Genomic DNA. Translation: AAC79607.1.
CP002685 Genomic DNA. Translation: AEC09615.1.
PIRiC84811.
RefSeqiNP_181428.1. NM_129452.4.
UniGeneiAt.255.
At.67089.

3D structure databases

ProteinModelPortaliQ96303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3818. 2 interactors.
STRINGi3702.AT2G38940.1.

PTM databases

iPTMnetiQ96303.

Proteomic databases

PaxDbiQ96303.
PRIDEiQ96303.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G38940.1; AT2G38940.1; AT2G38940.
GeneIDi818479.
GrameneiAT2G38940.1; AT2G38940.1; AT2G38940.
KEGGiath:AT2G38940.

Organism-specific databases

TAIRiAT2G38940.

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96303.
KOiK08176.
OMAiFFAPMIK.
OrthoDBiEOG093607P7.
PhylomeDBiQ96303.

Enzyme and pathway databases

BioCyciARA:GQT-2244-MONOMER.

Miscellaneous databases

PROiQ96303.

Gene expression databases

GenevisibleiQ96303. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHT14_ARATH
AccessioniPrimary (citable) accession number: Q96303
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 125 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Although related to the sugar transporter family, it does not transport sugars.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.