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Protein

14-3-3-like protein GF14 nu

Gene

GRF7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-ATH-1445148. Translocation of GLUT4 to the plasma membrane.
R-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371511. HSF1 activation.

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein GF14 nu
Alternative name(s):
General regulatory factor 7
Gene namesi
Name:GRF7
Ordered Locus Names:At3g02520
ORF Names:F16B3.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G02520.
TAIRilocus:2076904. AT3G02520.

Subcellular locationi

  • Nucleus By similarity
  • Cytoplasm By similarity

  • Note: Translocates from the cytosol to the nucleus when phosphorylated.By similarity

GO - Cellular componenti

  • chloroplast Source: TAIR
  • Golgi apparatus Source: TAIR
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000586691 – 26514-3-3-like protein GF14 nuAdd BLAST265

Proteomic databases

PaxDbiQ96300.
PRIDEiQ96300.

PTM databases

iPTMnetiQ96300.

Expressioni

Gene expression databases

ExpressionAtlasiQ96300. baseline and differential.
GenevisibleiQ96300. AT.

Interactioni

Subunit structurei

Component of the SERK1 signaling complex, composed of KAPP, CDC48A, GRF6 or GRF7, SERK1, SERK2, SERK3/BAK1 and BRI1 (PubMed:16473966). Interacts with DREB1A and DREB1B in the nucleus (PubMed:28344081).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi6393. 8 interactors.
IntActiQ96300. 9 interactors.
STRINGi3702.AT3G02520.1.

Structurei

3D structure databases

ProteinModelPortaliQ96300.
SMRiQ96300.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
HOGENOMiHOG000240379.
KOiK06630.
OMAiKKQQMGR.
OrthoDBiEOG09360IZO.
PhylomeDBiQ96300.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96300-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSREENVY LAKLAEQAER YEEMVEFMEK VAKTVDTDEL TVEERNLLSV
60 70 80 90 100
AYKNVIGARR ASWRIISSIE QKEESRGNDD HVSIIKDYRG KIETELSKIC
110 120 130 140 150
DGILNLLDSH LVPTASLAES KVFYLKMKGD YHRYLAEFKT GAERKEAAES
160 170 180 190 200
TLVAYKSAQD IALADLAPTH PIRLGLALNF SVFYYEILNS PDRACSLAKQ
210 220 230 240 250
AFDEAISELD TLGEESYKDS TLIMQLLRDN LTLWNSDIND EAGGDEIKEA
260
SKHEPEEGKP AETGQ
Length:265
Mass (Da):29,824
Last modified:February 1, 1997 - v1
Checksum:iBF76ECB7F76E166A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60445 mRNA. Translation: AAB49335.1.
AF145299 Genomic DNA. Translation: AAD51782.1.
AC021640 Genomic DNA. Translation: AAF32459.1.
CP002686 Genomic DNA. Translation: AEE73822.1.
CP002686 Genomic DNA. Translation: ANM65632.1.
AY065274 mRNA. Translation: AAL38750.1.
AY096526 mRNA. Translation: AAM20176.1.
AY087723 mRNA. Translation: AAM65260.1.
RefSeqiNP_001327587.1. NM_001337415.1.
NP_566174.1. NM_111119.3.
UniGeneiAt.21863.

Genome annotation databases

EnsemblPlantsiAT3G02520.1; AT3G02520.1; AT3G02520.
AT3G02520.2; AT3G02520.2; AT3G02520.
GeneIDi821060.
GrameneiAT3G02520.1; AT3G02520.1; AT3G02520.
AT3G02520.2; AT3G02520.2; AT3G02520.
KEGGiath:AT3G02520.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry namei14337_ARATH
AccessioniPrimary (citable) accession number: Q96300
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: June 7, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families