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Protein

Probable inorganic phosphate transporter 1-2

Gene

PHT1-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

High-affinity transporter for external inorganic phosphate.By similarity

GO - Molecular functioni

GO - Biological processi

  • cellular response to phosphate starvation Source: TAIR
  • phosphate ion transport Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Symport, Transport

Enzyme and pathway databases

BioCyciARA:GQT-1537-MONOMER.
ARA:GQT-764-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inorganic phosphate transporter 1-2
Short name:
AtPht1;2
Alternative name(s):
H(+)/Pi cotransporter
Gene namesi
Name:PHT1-2
Synonyms:APT1, PHT2
Ordered Locus Names:At5g43370
ORF Names:MWF20.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G43370.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2424CytoplasmicSequence analysisAdd
BLAST
Transmembranei25 – 4521HelicalSequence analysisAdd
BLAST
Topological domaini46 – 7025ExtracellularSequence analysisAdd
BLAST
Transmembranei71 – 9121HelicalSequence analysisAdd
BLAST
Topological domaini92 – 998CytoplasmicSequence analysis
Transmembranei100 – 12021HelicalSequence analysisAdd
BLAST
Topological domaini121 – 13111ExtracellularSequence analysisAdd
BLAST
Transmembranei132 – 15221HelicalSequence analysisAdd
BLAST
Topological domaini153 – 1619CytoplasmicSequence analysis
Transmembranei162 – 18221HelicalSequence analysisAdd
BLAST
Topological domaini183 – 21129ExtracellularSequence analysisAdd
BLAST
Transmembranei212 – 23221HelicalSequence analysisAdd
BLAST
Topological domaini233 – 29260CytoplasmicSequence analysisAdd
BLAST
Transmembranei293 – 31321HelicalSequence analysisAdd
BLAST
Topological domaini314 – 34835ExtracellularSequence analysisAdd
BLAST
Transmembranei349 – 36921HelicalSequence analysisAdd
BLAST
Topological domaini370 – 3712CytoplasmicSequence analysis
Transmembranei372 – 39221HelicalSequence analysisAdd
BLAST
Topological domaini393 – 40210ExtracellularSequence analysis
Transmembranei403 – 42321HelicalSequence analysisAdd
BLAST
Topological domaini424 – 44118CytoplasmicSequence analysisAdd
BLAST
Transmembranei442 – 46221HelicalSequence analysisAdd
BLAST
Topological domaini463 – 48422ExtracellularSequence analysisAdd
BLAST
Transmembranei485 – 50521HelicalSequence analysisAdd
BLAST
Topological domaini506 – 52419CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 524524Probable inorganic phosphate transporter 1-2PRO_0000050469Add
BLAST

Proteomic databases

PaxDbiQ96243.
PRIDEiQ96243.

Expressioni

Tissue specificityi

Root specific, especially in trichoblasts. In mature plants, localized in root cortical cells and young lateral roots.2 Publications

Inductioni

In roots by phosphate starvation.2 Publications

Gene expression databases

GenevisibleiQ96243. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G43370.1.

Structurei

3D structure databases

ProteinModelPortaliQ96243.
SMRiQ96243. Positions 69-103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96243.
KOiK08176.
OMAiNMIATCA.
OrthoDBiEOG093607P7.
PhylomeDBiQ96243.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96243-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEQQLGVLK ALDVAKTQLY HFTAIVIAGM GFFTDAYDLF CVSLVTKLLG
60 70 80 90 100
RIYYFNPESA KPGSLPPHVA AAVNGVALCG TLSGQLFFGW LGDKLGRKKV
110 120 130 140 150
YGLTLIMMIL CSVASGLSFG NEAKGVMTTL CFFRFWLGFG IGGDYPLSAT
160 170 180 190 200
IMSEYANKKT RGAFIAAVFA MQGVGILAGG FVALAVSSIF DKKFPAPTYA
210 220 230 240 250
VNRALSTPPQ VDYIWRIIVM FGALPAALTY YWRMKMPETA RYTALVAKNI
260 270 280 290 300
KQATADMSKV LQTDIELEER VEDDVKDPRQ NYGLFSKEFL RRHGLHLLGT
310 320 330 340 350
TSTWFLLDIA FYSQNLFQKD IFSAIGWIPK AATMNATHEV FRIARAQTLI
360 370 380 390 400
ALCSTVPGYW FTVAFIDTIG RFKIQLNGFF MMTVFMFAIA FPYNHWIKPE
410 420 430 440 450
NRIGFVVMYS LTFFFANFGP NATTFIVPAE IFPARLRSTC HGISAAAGKA
460 470 480 490 500
GAIIGAFGFL YAAQNQDKAK VDAGYPPGIG VKNSLIVLGV LNFIGMLFTF
510 520
LVPEPKGKSL EELSGEAEVS HDEK
Length:524
Mass (Da):57,644
Last modified:January 10, 2006 - v2
Checksum:i54664D4CD3ABE9D7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti418 – 4181F → L in CAA68945 (PubMed:9025304).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07681 Genomic DNA. Translation: CAA68945.1.
AB000094 Genomic DNA. Translation: BAA24282.1.
AB025638 Genomic DNA. Translation: BAA97416.1.
CP002688 Genomic DNA. Translation: AED94950.1.
CP002688 Genomic DNA. Translation: AED94951.1.
RefSeqiNP_001190462.1. NM_001203533.1.
NP_199151.1. NM_123703.2.
UniGeneiAt.25234.
At.75586.

Genome annotation databases

EnsemblPlantsiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
GeneIDi834355.
GrameneiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
KEGGiath:AT5G43370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07681 Genomic DNA. Translation: CAA68945.1.
AB000094 Genomic DNA. Translation: BAA24282.1.
AB025638 Genomic DNA. Translation: BAA97416.1.
CP002688 Genomic DNA. Translation: AED94950.1.
CP002688 Genomic DNA. Translation: AED94951.1.
RefSeqiNP_001190462.1. NM_001203533.1.
NP_199151.1. NM_123703.2.
UniGeneiAt.25234.
At.75586.

3D structure databases

ProteinModelPortaliQ96243.
SMRiQ96243. Positions 69-103.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G43370.1.

Proteomic databases

PaxDbiQ96243.
PRIDEiQ96243.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
GeneIDi834355.
GrameneiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
KEGGiath:AT5G43370.

Organism-specific databases

TAIRiAT5G43370.

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96243.
KOiK08176.
OMAiNMIATCA.
OrthoDBiEOG093607P7.
PhylomeDBiQ96243.

Enzyme and pathway databases

BioCyciARA:GQT-1537-MONOMER.
ARA:GQT-764-MONOMER.

Miscellaneous databases

PROiQ96243.

Gene expression databases

GenevisibleiQ96243. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHT12_ARATH
AccessioniPrimary (citable) accession number: Q96243
Secondary accession number(s): O48640
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: September 7, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Although related to the sugar transporter family, it does not transport sugars.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.