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Protein

Probable inorganic phosphate transporter 1-2

Gene

PHT1-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

High-affinity transporter for external inorganic phosphate.By similarity

GO - Molecular functioni

GO - Biological processi

  • cellular response to phosphate starvation Source: TAIR
  • phosphate ion transport Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inorganic phosphate transporter 1-2
Short name:
AtPht1;2
Alternative name(s):
H(+)/Pi cotransporter
Gene namesi
Name:PHT1-2
Synonyms:APT1, PHT2
Ordered Locus Names:At5g43370
ORF Names:MWF20.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G43370.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 70ExtracellularSequence analysisAdd BLAST25
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 99CytoplasmicSequence analysis8
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Topological domaini121 – 131ExtracellularSequence analysisAdd BLAST11
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Topological domaini153 – 161CytoplasmicSequence analysis9
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 211ExtracellularSequence analysisAdd BLAST29
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21
Topological domaini233 – 292CytoplasmicSequence analysisAdd BLAST60
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21
Topological domaini314 – 348ExtracellularSequence analysisAdd BLAST35
Transmembranei349 – 369HelicalSequence analysisAdd BLAST21
Topological domaini370 – 371CytoplasmicSequence analysis2
Transmembranei372 – 392HelicalSequence analysisAdd BLAST21
Topological domaini393 – 402ExtracellularSequence analysis10
Transmembranei403 – 423HelicalSequence analysisAdd BLAST21
Topological domaini424 – 441CytoplasmicSequence analysisAdd BLAST18
Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Topological domaini463 – 484ExtracellularSequence analysisAdd BLAST22
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21
Topological domaini506 – 524CytoplasmicSequence analysisAdd BLAST19

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504691 – 524Probable inorganic phosphate transporter 1-2Add BLAST524

Proteomic databases

PaxDbiQ96243.

Expressioni

Tissue specificityi

Root specific, especially in trichoblasts. In mature plants, localized in root cortical cells and young lateral roots.2 Publications

Inductioni

In roots by phosphate starvation.2 Publications

Gene expression databases

GenevisibleiQ96243. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G43370.1.

Structurei

3D structure databases

ProteinModelPortaliQ96243.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96243.
KOiK08176.
OMAiNMIATCA.
OrthoDBiEOG093607P7.
PhylomeDBiQ96243.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96243-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEQQLGVLK ALDVAKTQLY HFTAIVIAGM GFFTDAYDLF CVSLVTKLLG
60 70 80 90 100
RIYYFNPESA KPGSLPPHVA AAVNGVALCG TLSGQLFFGW LGDKLGRKKV
110 120 130 140 150
YGLTLIMMIL CSVASGLSFG NEAKGVMTTL CFFRFWLGFG IGGDYPLSAT
160 170 180 190 200
IMSEYANKKT RGAFIAAVFA MQGVGILAGG FVALAVSSIF DKKFPAPTYA
210 220 230 240 250
VNRALSTPPQ VDYIWRIIVM FGALPAALTY YWRMKMPETA RYTALVAKNI
260 270 280 290 300
KQATADMSKV LQTDIELEER VEDDVKDPRQ NYGLFSKEFL RRHGLHLLGT
310 320 330 340 350
TSTWFLLDIA FYSQNLFQKD IFSAIGWIPK AATMNATHEV FRIARAQTLI
360 370 380 390 400
ALCSTVPGYW FTVAFIDTIG RFKIQLNGFF MMTVFMFAIA FPYNHWIKPE
410 420 430 440 450
NRIGFVVMYS LTFFFANFGP NATTFIVPAE IFPARLRSTC HGISAAAGKA
460 470 480 490 500
GAIIGAFGFL YAAQNQDKAK VDAGYPPGIG VKNSLIVLGV LNFIGMLFTF
510 520
LVPEPKGKSL EELSGEAEVS HDEK
Length:524
Mass (Da):57,644
Last modified:January 10, 2006 - v2
Checksum:i54664D4CD3ABE9D7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti418F → L in CAA68945 (PubMed:9025304).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07681 Genomic DNA. Translation: CAA68945.1.
AB000094 Genomic DNA. Translation: BAA24282.1.
AB025638 Genomic DNA. Translation: BAA97416.1.
CP002688 Genomic DNA. Translation: AED94950.1.
CP002688 Genomic DNA. Translation: AED94951.1.
RefSeqiNP_001190462.1. NM_001203533.1.
NP_199151.1. NM_123703.3.
UniGeneiAt.25234.
At.75586.

Genome annotation databases

EnsemblPlantsiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
GeneIDi834355.
GrameneiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
KEGGiath:AT5G43370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07681 Genomic DNA. Translation: CAA68945.1.
AB000094 Genomic DNA. Translation: BAA24282.1.
AB025638 Genomic DNA. Translation: BAA97416.1.
CP002688 Genomic DNA. Translation: AED94950.1.
CP002688 Genomic DNA. Translation: AED94951.1.
RefSeqiNP_001190462.1. NM_001203533.1.
NP_199151.1. NM_123703.3.
UniGeneiAt.25234.
At.75586.

3D structure databases

ProteinModelPortaliQ96243.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G43370.1.

Proteomic databases

PaxDbiQ96243.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
GeneIDi834355.
GrameneiAT5G43370.1; AT5G43370.1; AT5G43370.
AT5G43370.2; AT5G43370.2; AT5G43370.
KEGGiath:AT5G43370.

Organism-specific databases

TAIRiAT5G43370.

Phylogenomic databases

eggNOGiKOG0252. Eukaryota.
ENOG410ZVN7. LUCA.
HOGENOMiHOG000171120.
InParanoidiQ96243.
KOiK08176.
OMAiNMIATCA.
OrthoDBiEOG093607P7.
PhylomeDBiQ96243.

Miscellaneous databases

PROiQ96243.

Gene expression databases

GenevisibleiQ96243. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004738. Phos_permease.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00887. 2A0109. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPHT12_ARATH
AccessioniPrimary (citable) accession number: Q96243
Secondary accession number(s): O48640
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 30, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Although related to the sugar transporter family, it does not transport sugars.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.