Q961E0 (Q961E0_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GM14815p EMBL AAK93072.1

Gene names

Name:	Cul-4 FlyBase FBgn0033260
Synonyms:	cul-4 EMBL AAK93072.1
ORF Names:	CG8711 FlyBase FBgn0033260

Organism

Drosophila melanogaster (Fruit fly) EMBL AAK93072.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cullin family. RuleBase RU003829

Ontologies

Gene Ontology (GO)
Biological process	eggshell chorion gene amplification Inferred from direct assay. Source: FlyBase mitotic cell cycle G2/M transition DNA damage checkpoint Inferred from genetic interaction. Source: FlyBase positive regulation of NFAT protein import into nucleus Inferred from mutant phenotype. Source: FlyBase ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cullin-RING ubiquitin ligase complex Inferred from electronic annotation. Source: InterPro
Molecular function	ubiquitin protein ligase binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q961E0 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 4925604E06D0FEBB	FASTA	601	69,933
	10 20 30 40 50 60 MCCKIRPFTR FGTWGWTFFR IHFAQNSVVQ KRTVDGLLTL IEKERQGSTV DRGLLKSLVR 70 80 90 100 110 120 MLCDLQIYTS SFEEKFLDAT NQLYKAESQR KMQELEVPEY LQHVNKRLAE ENERLRHYLD 130 140 150 160 170 180 SSTKHPLIYN VEKELLAEHL TSILQKGLDS LLEDNRLSDL TLLYGLLSRV KNGTSELCGN 190 200 210 220 230 240 FNGFIKKKGR TIVIDPEKDK SMVQDLLDFK DKMDVIVRTC FEHNEKFTNS LREAFEFFIN 250 260 270 280 290 300 QRANKPAELI AKYVDMKLRS GNKGTTDEEL EKTLDKIMVL FRFIHGKDVF EAFYKKDLAK 310 320 330 340 350 360 RLLVGKSASV DSEKSMLSKL KQECGGGFTS KLEGMFKDME LSRDINIAFR GHALSNNRDV 370 380 390 400 410 420 HNLDLCVSIL TMGYWPTYAP TEVTMPPQFI NPQQIFNKFY LEKHSGRKLQ WQPTLGNCML 430 440 450 460 470 480 RAQFDAGPKE LLVSLFQALV LLLFNDKPVL SYEEILAATL IEDGELRRTL QSLACGRARV 490 500 510 520 530 540 ITKTPKGREI LDGDQFDFNN EFTNKLFRIK INQIQMKETN EEQKATEERV FQDRQYQIDA 550 560 570 580 590 600 AIVRIMKMRK TLSHNLLITE LFNQLTFPVK PADLKKRIES LIDRDYMERD KDNQNQYNYV A

References

[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY051648 mRNA. Translation: AAK93072.1.
3D structure databases
HSSP	HSSP built from PDB template 1IUY based on UniProtKB Q9JLV5.
ProteinModelPortal	Q961E0.
SMR	Q961E0. Positions 15-601.
ModBase	Search...
Protein-protein interaction databases
STRING	Q961E0.
Proteomic databases
PRIDE	Q961E0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0033260. Cul-4.
Phylogenomic databases
eggNOG	inNOG05472.
GeneTree	EMGT00050000011118.
InParanoid	Q961E0.
Gene expression databases
ArrayExpress	Q961E0.
Bgee	Q961E0.
Family and domain databases
InterPro	IPR016157. Cullin_CS. IPR016158. Cullin_homology. IPR001373. Cullin_N. IPR019559. Cullin_neddylation_domain. IPR016159. Cullin_repeat-like_dom. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 2 hits.
Pfam	PF00888. Cullin. 1 hit. PF10557. Cullin_Nedd8. 1 hit. [Graphical view]
SMART	SM00182. CULLIN. 1 hit. SM00884. Cullin_Nedd8. 1 hit. [Graphical view]
SUPFAM	SSF75632. Cullin_homology. 1 hit. SSF74788. Cullin_repeat-like. 1 hit.
PROSITE	PS01256. CULLIN_1. 1 hit. PS50069. CULLIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q961E0_DROME

Accession

Primary (citable) accession number: Q961E0

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	November 16, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)