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Q961C9 (TNG11_DROME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transport and Golgi organization protein 11

Short name=Tango-11
Gene names
Name:Tango11
ORF Names:CG30404
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein Ref.4.

Sequence similarities

Belongs to the tango11 family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

CG3563Q9VFG31EBI-95452,EBI-192116

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Transport and Golgi organization protein 11
PRO_0000289192

Regions

Topological domain1 – 256256Cytoplasmic Potential
Transmembrane257 – 27418Helical; Anchor for type IV membrane protein; Potential
Topological domain275 – 2773Lumenal Potential
Coiled coil225 – 25329 Potential

Amino acid modifications

Modified residue1271Phosphoserine Ref.5
Modified residue1291Phosphoserine Ref.5
Modified residue1321Phosphoserine Ref.5
Modified residue1331Phosphoserine Ref.5
Modified residue1771Phosphothreonine Ref.5
Modified residue1791Phosphoserine Ref.5
Modified residue1821Phosphoserine Ref.5
Modified residue1901Phosphoserine Ref.5
Modified residue2161Phosphothreonine Ref.5
Modified residue2221Phosphothreonine Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q961C9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 73589873005CAC92

FASTA27731,541
        10         20         30         40         50         60 
MVTPQSPTPM FNGLDDDLYS DAKYAHEIND KMRVPKRIKA TGEYSNEDLL LSNQNGMISS 

        70         80         90        100        110        120 
WNYHDKIDMN VPDRIVVLGH NQHLETRSAP REIQLENSIL PKNPSVGLVR VQTPPRIITL 

       130        140        150        160        170        180 
TDQHFPSASE ESSPIRANGH HLYGNDLDED ADDEEVHATQ YVRANGVARM GFQGNDTNSV 

       190        200        210        220        230        240 
ESDSQLTTGS ASKRSQLNQQ QHNNLDASML AHREGTPMGE LTPHEEILYL RRQLAKLNRR 

       250        260        270 
VLNIEINNEQ RTQREKIVYC LGLAYFVLKT IFWLNRN 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[3]"A Drosophila full-length cDNA resource."
Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E.
Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Berkeley.
Tissue: Embryo.
[4]"Functional genomics reveals genes involved in protein secretion and Golgi organization."
Bard F., Casano L., Mallabiabarrena A., Wallace E., Saito K., Kitayama H., Guizzunti G., Hu Y., Wendler F., Dasgupta R., Perrimon N., Malhotra V.
Nature 439:604-607(2006) [PubMed: 16452979] [Abstract]
Cited for: SUBCELLULAR LOCATION.
[5]"Phosphoproteome analysis of Drosophila melanogaster embryos."
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127; SER-129; SER-132; SER-133; THR-177; SER-179; SER-182; SER-190; THR-216 AND THR-222, MASS SPECTROMETRY.
Tissue: Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013599 Genomic DNA. Translation: AAM71012.1.
AY051672 mRNA. Translation: AAK93096.1.
RefSeqNP_726111.1. NM_166481.2.
NP_726112.1. NM_166482.2.
UniGeneDm.20857.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ961C9. 1 interaction.
MINTMINT-961545.

Proteomic databases

PRIDEQ961C9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0071746; FBpp0071660; FBgn0050404.
FBtr0071747; FBpp0071661; FBgn0050404.
GeneID246596.
KEGGdme:Dmel_CG30404.

Organism-specific databases

CTD246596.
FlyBaseFBgn0050404. Tango11.

Phylogenomic databases

eggNOGinNOG09779.
GeneTreeEMGT00050000017958.
InParanoidQ961C9.
OMAHEINDKM.
OrthoDBEOG4RXWGB.
PhylomeDBQ961C9.

Gene expression databases

BgeeQ961C9.

Family and domain databases

InterProIPR008518. DUF800.
[Graphical view]
PANTHERPTHR16501. DUF800. 1 hit.
PfamPF05644. DUF800. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio843148.

Entry information

Entry nameTNG11_DROME
AccessionPrimary (citable) accession number: Q961C9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

SIMILARITY comments

Index of protein domains and families