Unreviewed, UniProtKB/TrEMBL Q961C5 (Q961C5_DROME)

Names and origin

Protein names

Submitted name:
    Alphabet, isoform E EMBL AAN14176.1
Submitted name:
    LD23542p EMBL AAK93109.1

Gene names

Name:	alph FlyBase FBgn0086361
ORF Names:	CG1906 EMBL AAK93109.1 FlyBase FBgn0039672, Dmel_CG1906 EMBL AAN14176.1

Organism

Drosophila melanogaster (Fruit fly) EMBL AAK93109.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the PP2C family. RuleBase RU003465V0

Ontologies

Keywords
Ligand	Magnesium RuleBase RU003465V0 Metal-binding RuleBase RU003465V0
Molecular function	Hydrolase Protein phosphatase RuleBase RU003465V0
Gene Ontology (GO)
Biological process	imaginal disc-derived wing morphogenesis Inferred from mutant phenotype. Source: FlyBase mitotic cell cycle Inferred from mutant phenotype. Source: FlyBase negative regulation of MAP kinase activity Inferred from mutant phenotype. Source: FlyBase negative regulation of Ras protein signal transduction Inferred from mutant phenotype. Source: FlyBase positive regulation of R7 cell differentiation Inferred from genetic interaction. Source: FlyBase protein amino acid dephosphorylation Inferred from electronic annotation. Source: InterPro
Cellular component	protein serine/threonine phosphatase complex Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: InterPro protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q961C5-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 37CA399271627F7D	FASTA	374	41,629
	10 20 30 40 50 60 MGGFLDKPKT AKHNDEGEGN KLLFGVSSMQ GWRSEMEDAY YARAGLGDAL PDWSFFAVFD 70 80 90 100 110 120 GHAGCKVSEH CAKHLLESII STEEFIGGDH VKGIRTGFLR IDEVMRELPE FTRESEKCGG 130 140 150 160 170 180 TTAVCAFVGL TQVYIANCGD SRAVLCRQGV PVFATQDHKP ILPEEKERIY NAGGSVMIKR 190 200 210 220 230 240 VNGTLAVSRA LGDYDFKNVK EKGQCEQLVS PEPEIFCQSR QDSDEFLVLA CDGIWDVMSN 250 260 270 280 290 300 EDVCSFIHSR MRVTSNLVSI ANQVVDTCLH KGSRDNMSII IIAFPGAPKP TEEAIEAEHR 310 320 330 340 350 360 LEKQIEKITR DEIESSKITD YVDLLKCLQN RDDIEGLPPG GGLQSKYHVI ERTFKQEFPD 370 RPCEGNGISY FIPF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAK93109.1.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY051685 mRNA. Translation: AAK93109.1. AE014297 Genomic DNA. Translation: AAN14176.1.
RefSeq	NP_651701.1.
UniGene	Dm.7085
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ModBase	Search...
Proteomic databases
PRIDE	Q961C5.
Genome annotation databases
Ensembl	FBgn0086361. Drosophila melanogaster. [Contig view]
GeneID	43481.
KEGG	dme:Dmel_CG1906.
Organism-specific databases
FlyBase	FBgn0086361. alph.
Phylogenomic databases
HOGENOM	Q961C5.
OMA	Q961C5. XIMEKSG.
Gene expression databases
ArrayExpress	Q961C5.
Family and domain databases
InterPro	IPR015655. PP2C. IPR001932. PP2C-related. IPR012911. PP2C_C. IPR000222. PP2C_Mn2_Asp60_BS. IPR014045. PP2C_N. [Graphical view]
Gene3D	G3DSA:3.60.40.10. PP2C-related. 1 hit. G3DSA:1.10.10.430. PP2C_C. 1 hit.
PANTHER	PTHR13832. PP2C. 1 hit.
Pfam	PF00481. PP2C. 1 hit. PF07830. PP2C_C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	834154.

Entry information

Entry name

Q961C5_DROME

Accession

Primary (citable) accession number: Q961C5

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)