Q960Y4 (Q960Y4_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LD29995p EMBL AAK93199.1

Gene names

Name:	drosha EMBL AAK93199.1
ORF Names:	CG8730 FlyBase FBgn0026722

Organism

Drosophila melanogaster (Fruit fly) EMBL AAK93199.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1071 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	primary miRNA processing Inferred from mutant phenotype. Source: FlyBase rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q960Y4 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 25E6C2AAADA5078B	FASTA	1,071	123,159
	10 20 30 40 50 60 MNALSEADAP VESWVRSSPA ELYYERTKSE NEVRGRARLQ KLCTLFDEEL LQRAKRVREK 70 80 90 100 110 120 LPVYVPPPRK ARRRVCKHKH KSEACSSSSS SDDDSDEDAF KIEQDCCMEE LSRKVQHPQR 130 140 150 160 170 180 VHADLWHNDA GEMNDGPLCR CSAKSRRIGI RHGIYPGETG YKLCDPNSNN AGKLFHYRIS 190 200 210 220 230 240 ISPPTNFLTK TPTIIKHDEH EFLFEGFSLL SHVRLSDLPV CKVIRFNIEY TIEYEEEKMP 250 260 270 280 290 300 ENFTIHELDI FFKYLFHELL ELVDFNLMPN LPSGNVEESC PAFHFFPRFV RDLPDNGKEV 310 320 330 340 350 360 LAMVEVLRYL LDNSAQLVER QQLLHLNQIS QSEWQNYVDF IKGMLVTKPG YKPCSLRVDQ 370 380 390 400 410 420 LDRNNSDLPE CVDRETGISH PAIVHFGICH PQLSYAGNPE YQKAWREYVK YRHLMANMSK 430 440 450 460 470 480 PSFKDKRKLE EKEQRLQEMR TQGRMKRNIT VAISSEGFYR TGIMCDVVQH AMLIPVLTGH 490 500 510 520 530 540 LRFHKSLDLL EESIGYRFKN RYLLQLALTH PSYKENYGTN PDHARNSLTN CGIRQPEYGD 550 560 570 580 590 600 RKIHYMNTRK RGINTLVSIM SRFGKEHETV SNITHNERLE FLGDAVVEFL SSIHLFFMFP 610 620 630 640 650 660 ELEEGGLATY RAAIVQNQHL ALLAKKLQLE EFMLYAHGSD LCHELELRHA MANCFEALMG 670 680 690 700 710 720 ALLLDGGIKV ADEVFTDALF RQDEKLLSIW KNLPEHPLQE QEPLGDRSCI DSYRVLKELT 730 740 750 760 770 780 KFEDSIGIKF KHIRLLARAF TDRSIGFTHL TLGSNQRLEF LGDTVLQLIC SEYLYRHFPE 790 800 810 820 830 840 HHEGHLSLLR SSLVNNRTQA VVCDDLGMPK YAVYANPKAD LKTKDRADLL EAFLGALYVD 850 860 870 880 890 900 KGLLYCEQFC HVCLFPRLQL FIMNQDWNDP KSKLQQCCLT LRTMDGGEPD IPYYKVVEAS 910 920 930 940 950 960 GPTNTRVYKV AVYFRSKRLA TSSGSSIQQA EMNAAKQALE NSRDLFPQLD HQKRVIAKSI 970 980 990 1000 1010 1020 KKQTGNELDN DSDRQHQEEK IKRPKYATPL QDESHLPKQY RMHENISSDE LPEDEDFEST 1030 1040 1050 1060 1070 APKSPTMPLR SNRSGSSSSS SSSDSDGSTS SPKCKRRLKK CSSVSSKSSL G

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAK93199.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY051775 mRNA. Translation: AAK93199.1.
3D structure databases
HSSP	HSSP built from PDB template 1JFZ based on UniProtKB O67082.
ProteinModelPortal	Q960Y4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q960Y4.
Proteomic databases
PRIDE	Q960Y4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
NMPDR	fig|7227.3.peg.3769.
Organism-specific databases
FlyBase	FBgn0026722. drosha.
Phylogenomic databases
eggNOG	inNOG05402.
GeneTree	EMGT00050000006191.
InParanoid	Q960Y4.
Gene expression databases
ArrayExpress	Q960Y4.
Bgee	Q960Y4.
Family and domain databases
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 3 hits.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 2 hits. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 2 hits. [Graphical view]
SUPFAM	SSF69065. RNase_III. 2 hits.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q960Y4_DROME

Accession

Primary (citable) accession number: Q960Y4

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)