ID   SAP47_DROME             Reviewed;         551 AA.
AC   Q960T2-1;
DT   09-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   24-JAN-2024, entry version 137.
DE   RecName: Full=Isoform A of Synapse-associated protein of 47 kDa;
GN   Name=Sap47; ORFNames=CG8884;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS F AND I), AND TISSUE SPECIFICITY.
RC   STRAIN=Berlin; TISSUE=Head;
RX   PubMed=7494462; DOI=10.1016/0169-328x(95)00058-z;
RA   Reichmuth C., Becker S., Benz M., Debel K., Reisch D., Heimbeck G.,
RA   Hofbauer A., Klagges B., Pflugfelder G.O., Buchner E.;
RT   "The sap47 gene of Drosophila melanogaster codes for a novel conserved
RT   neuronal protein associated with synaptic terminals.";
RL   Brain Res. Mol. Brain Res. 32:45-54(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [3]
RP   GENOME REANNOTATION, AND ALTERNATIVE SPLICING.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A).
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
RN   [5]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-178; SER-182; THR-186;
RP   SER-433 AND THR-530, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC   TISSUE=Embryo;
RX   PubMed=18327897; DOI=10.1021/pr700696a;
RA   Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
RT   "Phosphoproteome analysis of Drosophila melanogaster embryos.";
RL   J. Proteome Res. 7:1675-1682(2008).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=5;
CC       Name=A; Synonyms=C, D, E, H;
CC         IsoId=Q960T2-1; Sequence=Displayed;
CC       Name=B;
CC         IsoId=Q960T2-2; Sequence=VSP_007393, VSP_007394;
CC       Name=F; Synonyms=1;
CC         IsoId=Q960T2-4; Sequence=VSP_007389, VSP_007390, VSP_007393,
CC                                  VSP_007394;
CC       Name=G;
CC         IsoId=Q960T2-5; Sequence=VSP_007389;
CC       Name=I; Synonyms=2;
CC         IsoId=Q960T2-3; Sequence=VSP_007389, VSP_007390, VSP_007391,
CC                                  VSP_007392;
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DR   RefSeq; NP_732088.1; NM_169684.3.
DR   RefSeq; NP_732089.1; NM_169685.3.
DR   RefSeq; NP_732090.1; NM_169686.3.
DR   RefSeq; NP_732091.1; NM_169687.3.
DR   EnsemblMetazoa; FBtr0083204; FBpp0082658; FBgn0013334.
DR   EnsemblMetazoa; FBtr0083206; FBpp0082660; FBgn0013334.
DR   EnsemblMetazoa; FBtr0083207; FBpp0082661; FBgn0013334.
DR   EnsemblMetazoa; FBtr0083208; FBpp0082662; FBgn0013334.
DR   Proteomes; UP000000803; Chromosome 3R.
PE   1: Evidence at protein level;
SQ   SEQUENCE   551 AA;  56980 MW;  430392D0EAD5916E CRC64;
     MFSGLTNQFT SLVGAVKGGA GDEDVPAPTG DAPAAAPAAS TSVEATASSA VDPEAAAAAG
     GEGLEGEEAG KRLPKSASLV DSLVSEATGW LGSAKGWLGN ASIPSMPAMP SMPSMPAMPA
     MPSIPSIPGL RKGAGADGAE GAEGAVAGEG GAAASGAVSG GEDDDKSRYI SATEGADSHP
     ASGGGTPTGD EGQIGQGKGD EVKITTKVTQ QAKHFGSFLS SAISKAGSKI KETVKDNTIL
     DSFNKEQEAF IKGQGGVGNG AAPWIGHANE AKIKEEILGL SQDRRNFVRA PPAGVDFEFS
     YDTAYPTAIA IMAEDKALET MRFELVPKII TEENFWRNYF YRVSLIIQAA ELGTLGADGV
     GQASSGEDAN EVATKEKKSK TAEPAKGDSS VKAIAEQPKA VIEPEAQECD VQAAKSKAKA
     KAQAGKELGQ KISESEFVSD DFQASSESDL AEIQDGMRKL GIDSMTQQAL AATDEEQWEK
     DLEAELKDYE VVDEGGTGGD GGGGRRKGRK AGEDDTEADE DEPTISNLRT RSTNNDWEEY
     ADLIEDTDDL K
//