ID   Q95Y95_CAEEL            Unreviewed;       652 AA.
AC   Q95Y95;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 2.
DT   24-JAN-2024, entry version 131.
DE   SubName: Full=IMD domain-containing protein {ECO:0000313|EMBL:CCD64227.1};
GN   ORFNames=CELE_M04F3.5 {ECO:0000313|EMBL:CCD64227.1}, M04F3.5
GN   {ECO:0000313|EMBL:CCD64227.1, ECO:0000313|WormBase:M04F3.5b};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD64227.1, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:CCD64227.1, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD64227.1,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- INTERACTION:
CC       Q95Y95; Q10929: abi-1; NbExp=4; IntAct=EBI-2315841, EBI-315750;
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DR   EMBL; BX284601; CCD64227.1; -; Genomic_DNA.
DR   RefSeq; NP_491448.2; NM_059047.6.
DR   AlphaFoldDB; Q95Y95; -.
DR   SMR; Q95Y95; -.
DR   IntAct; Q95Y95; 1.
DR   EPD; Q95Y95; -.
DR   PaxDb; 6239-M04F3-5; -.
DR   PeptideAtlas; Q95Y95; -.
DR   EnsemblMetazoa; M04F3.5b.1; M04F3.5b.1; WBGene00019771.
DR   GeneID; 172093; -.
DR   UCSC; M04F3.5; c. elegans.
DR   AGR; WB:WBGene00019771; -.
DR   WormBase; M04F3.5b; CE31974; WBGene00019771; -.
DR   eggNOG; ENOG502QRG4; Eukaryota.
DR   GeneTree; ENSGT00950000183156; -.
DR   HOGENOM; CLU_030999_0_0_1; -.
DR   OMA; NSWRSCL; -.
DR   OrthoDB; 3875239at2759; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00019771; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR   ExpressionAtlas; Q95Y95; baseline and differential.
DR   GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IDA:WormBase.
DR   GO; GO:0030175; C:filopodium; IDA:WormBase.
DR   GO; GO:0003779; F:actin binding; IBA:GO_Central.
DR   GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR   GO; GO:0030031; P:cell projection assembly; IDA:WormBase.
DR   GO; GO:0061024; P:membrane organization; IDA:WormBase.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF4; FI21477P1-RELATED; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:Q95Y95,
KW   ECO:0007829|PeptideAtlas:Q95Y95};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT   DOMAIN          1..244
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   REGION          253..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          290..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          511..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          567..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..539
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   652 AA;  70654 MW;  850E6B91AB02ADC0 CRC64;
     MDPDAEFNLL TTLYQSVVHD MKHTYPGWDA LSQKAQKLGT QLRATAQCLS TFTEAMQGVC
     DNANNLKGAS RDVGACVTRV CIKQRAIENR MRSWADALCE ELAISLQQRG NYWKSRCHDM
     DKTAAKHVKK VRSRKQRPDV TAMNEQREIC TKVLTEQRTQ FSFFIGTLMP VLNAQMNMLD
     EGAHLRQVVD NLDSTVKHVD TEQLVSSIVS DIAQGPDSAW KQCLAQAGNK WRSSEDGYSC
     MGSIRDLSTR ATTPASNFSS EDGMHTLTGN GLGGTTRSIS TSCTRNLPLI TGNGNMESSA
     SSVISSSTRY SKPPLQRRNS EKSIGHYSMS SPNTDGSSTY LNLMGNGAGN SSSNTITEMS
     QYQQQHHQPV IRAVSNGTHS NAPPAYQQYI NQRQQNGGSI PRPQNLAFEP FNPTTSIGAT
     PTVYHPATPA TTSSGGQPET SPGSSATSAS AFLISEACRD IDQLGSDLEN YCSVQDPTRY
     FIHESSPSSG QKNGTPPAAT NTMIAAMIQR RASHAGDYQQ QQTMSDPGKR ASVSTLGSSN
     MSNYGVLSHQ PPLPQSANSM QNQQVRMRTT SASRPPPPAR RTSQITAATP TAPSVAEQRM
     NGSTMGSRQS LDSAGLYDPA HPQQFYQMSS FNRSNNVNGQ ASATAAAAKF RI
//