Q95W15 (Q95W15_9TRYP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: RNA-editing complex protein MP81 EMBL AAK64278.1
Organism	Trypanosoma brucei EMBL AAK64278.1
Taxonomic identifier	5691 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Trypanozoon

Protein attributes

Sequence length	762 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4DK3 PDB 4DK6 PDB 4DKA
Gene Ontology (GO)
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q95W15 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: F8E8E38A3645A358	FASTA	762	81,294
	10 20 30 40 50 60 MRRLTRRSGR LSGKGNGGSC LQMSPTHVGA VVTWALNRLM PLHTRTIPLR CSLPTPESGT 70 80 90 100 110 120 TEPRELCFYE TFELTEEDVH YLLLHEAHVK HGVLLNVPPQ LAPNGTPPEV PEVIMPAAQL 130 140 150 160 170 180 ERMGGMKLAY EPTHLPPPLH TTGARQLVLD ESFYTTPTKE KKATTTAVSH VSESTAASGG 190 200 210 220 230 240 RGGASATAAG TALPPRLPPD PTMKFHCSAC GKAFRLKFSA DHHVKLNHGS DPKAAVVDGP 250 260 270 280 290 300 GEGELLGGAV TITTAKVAKH SSSAASGTAS RAGDSATLDV KQQPDPQKEL SAPGISAVKI 310 320 330 340 350 360 PYSKAVLSLP DDELVDELLI DVWDAVAAQR DDVPKSNSAN IFLPFASVVT GTADRRKEME 370 380 390 400 410 420 AVARPTARAT PEGAAPGIKR PGAMAGGAVA VGKGRSGGQI LPIRELIKKY PNPFGDSPNA 430 440 450 460 470 480 AVQDLENEPL NPFLPEEELA AQLQVACEED TVVTPSACTT DVSTGSVIGK KGSLEKLKEK 490 500 510 520 530 540 LRGTRPSMAA SAAKRRFTCP ICVEKQQTLQ QQQSENVGSG FCTDIPSFRL LDALLDHVES 550 560 570 580 590 600 VHGEELTEDQ LRELYAKQRQ STLYPQKSST GDGAGSRETP DDSEKKEGSV GNTNMDELKS 610 620 630 640 650 660 LPEEVRRVVP PAPVEQDALA VHIRAGSNAL MIGRIADVQH GFLGAMTVTQ YVLEVDGDER 670 680 690 700 710 720 INSKGVTTPA SACTPDPAST KAVEAKGEEG EVVEPEKEFI VIRCMGDNFP ASLLKDQVKL 730 740 750 760 GSRVLVQGTL RMNRHVDDVS KRLHAYPFIQ VVPPLGYVKV VG

References

[1]	"Four related proteins of the Trypanosoma brucei RNA editing complex." Panigrahi A.K., Schnaufer A., Carmean N., Igo R.P. Jr, Gygi S.P., Ernst N.L., Palazzo S.S., Weston D.S., Aebersold R., Salavati R., Stuart K.D. Mol. Cell. Biol. 21:6833-6840(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: TREU427 EMBL AAK64278.1.
[2]	"The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2." Park Y.J., Budiarto T., Wu M., Pardon E., Steyaert J., Hol W.G. Nucleic Acids Res. 40:6966-6977(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.97 ANGSTROMS) OF 624-762.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF382333 Genomic DNA. Translation: AAK64278.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4DK3	X-ray	2.76	C/D	624-762	[»]
4DK6	X-ray	2.65	C/D	624-762	[»]
4DKA	X-ray	1.97	C/D	624-762	[»]

ModBase

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Protein-protein interaction databases

STRING

5691.Tb927.2.2470.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Organism-specific databases

EuPathDB

TriTrypDB:Tb427.02.2470.

Phylogenomic databases

eggNOG

NOG135082.

ProtClustDB

CLSZ2437307.

Family and domain databases

InterPro

IPR017085. RNA_edit_cplx_Nase-su_MP81.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
[Graphical view]

PIRSF

PIRSF037001. RNA_ed_MP81. 1 hit.

SMART

SM00355. ZnF_C2H2. 1 hit.
[Graphical view]

PROSITE

PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]

ProtoNet

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Entry information

Entry name

Q95W15_9TRYP

Accession

Primary (citable) accession number: Q95W15

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)