Q95TK2 (Q95TK2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LD45730p EMBL AAL13946.1

Gene names

Name:	mr FlyBase FBgn0002791
ORF Names:	CG3060 EMBL AAL13946.1 FlyBase FBgn0002791

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cullin family. RuleBase RU003829

Ontologies

Gene Ontology (GO)
Biological process	negative regulation of synaptic growth at neuromuscular junction Inferred from mutant phenotype. Source: FlyBase regulation of cell cycle Traceable author statement. Source: FlyBase regulation of synaptic transmission Inferred from mutant phenotype. Source: FlyBase ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	anaphase-promoting complex Traceable author statement. Source: FlyBase
Molecular function	ubiquitin protein ligase binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q95TK2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: C7791CE6B8E43C95	FASTA	449	51,620
	10 20 30 40 50 60 MRVYLTESLR NSLEARILHP GVNTMDILTG YVAAIKAIRH LDSTGVILEM VTAPIKDYLR 70 80 90 100 110 120 KRNDTVRRVV TGLTEEGPTD LSEELAKGET IKECKDSGTD EFSNWENWQP DPFGIDASIM 130 140 150 160 170 180 QYNSSRKMRS ADIISMVVDI YGSKELFMTE YRNLMADRLL AQLDFNSEKE IRNLELLKIR 190 200 210 220 230 240 FGESLLHSCE VMLKDVTDSK RINAHIHSDG DRTENQLFDI SSLIVSAQFW PSFNKESLQL 250 260 270 280 290 300 PEEIENEFKK YTKAYEAYKG NRTLNWRTVT GRVNIEIEIG DRTMEMVVSP ILAVIIYHFQ 310 320 330 340 350 360 TKNEWTIEDL SSITKVPASA LRRRLSFWQN HGLISETTPG IFTLLEKESE KSQYEDMSLA 370 380 390 400 410 420 EADEEDLESA MASASDQREE ELQVFWSYIV GMLTNLDSMP IDRIHQMLKL FASHSGGVEF 430 440 TQDELKHFLQ RKVREHKLIF SGGVYQLAK

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL13946.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY058717 mRNA. Translation: AAL13946.1.
3D structure databases
ProteinModelPortal	Q95TK2.
SMR	Q95TK2. Positions 378-448.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q95TK2. 1 interaction.
STRING	Q95TK2.
Proteomic databases
PRIDE	Q95TK2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0002791. mr.
Phylogenomic databases
eggNOG	inNOG04602.
InParanoid	Q95TK2.
OrthoDB	EOG4Q574J.
Gene expression databases
Bgee	Q95TK2.
Family and domain databases
InterPro	IPR014786. APC_su2_C. IPR016158. Cullin_homology. IPR001373. Cullin_N. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF08672. APC2. 1 hit. PF00888. Cullin. 1 hit. [Graphical view]
SMART	SM01013. APC2. 1 hit. SM00182. CULLIN. 1 hit. [Graphical view]
SUPFAM	SSF75632. Cullin_homology. 1 hit.
PROSITE	PS50069. CULLIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q95TK2_DROME

Accession

Primary (citable) accession number: Q95TK2

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)