Q95TJ9 (Q95TJ9_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cyclin G, isoform A EMBL AAF57168.2
EC=2.7.1.- EMBL AAF57168.2

Submitted name:
Cyclin G, isoform B EMBL AAF57170.2
EC=2.7.1.- EMBL AAF57170.2
Submitted name:
Cyclin G, isoform C EMBL AAF57169.2
EC=2.7.1.- EMBL AAF57169.2
Submitted name:
Cyclin G, isoform D EMBL AAF57171.2
EC=2.7.1.- EMBL AAF57171.2
Submitted name:
LD46284p EMBL AAL13949.1

Gene names

Name:	CycG EMBL AAF57170.2 FlyBase FBgn0039858
Synonyms:	CG11525 EMBL AAL13949.1
ORF Names:	Dmel_CG11525 EMBL AAF57168.2

Organism

Drosophila melanogaster (Fruit fly) EMBL AAL13949.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cyclin family. RuleBase RU000383

Ontologies

Keywords
Molecular function	Cyclin RuleBase RU000383 Transferase EMBL AAF57168.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	negative regulation of G1/S transition of mitotic cell cycle Inferred from genetic interaction. Source: FlyBase negative regulation of S phase of mitotic cell cycle Inferred from genetic interaction. Source: FlyBase
Cellular component	polytene chromosome Inferred from direct assay. Source: FlyBase
Molecular function	transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q95TJ9 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: E004BCC7F134E0F2	FASTA	566	62,791
	10 20 30 40 50 60 MSVPVRYSSA AAEYAAEVDC ELESTLQQQQ QLHLQQQYEQ YQHYQYQREQ DIAYYCQLQA 70 80 90 100 110 120 ARQQEQLMQQ RTSMSSSVMP GLALPQDHQD HPAALLNGPH NNNIGLAMDA HSINAILVDD 130 140 150 160 170 180 EQPSTSAQAA AAAAASAGGS AGAGSGSGLG GAIGGGKLAN GINRNAEMPT DWMRIADEGR 190 200 210 220 230 240 YGTPGAAGLE YQKYEQQQQL EDLAESEAGA VGGASNNNGE SSSSLKKLED QLHALTSDEL 250 260 270 280 290 300 YETLKEYDVL QDKFHTVLLL PKESRREVTA GGRDGSAYVL RCLKMWYELP SDVLFSAMSL 310 320 330 340 350 360 VDRFLDRMAV KPKHMACMSV ASFHLAIKQL DLKPIPAEDL VTISQCGCTA GDLERMAGVI 370 380 390 400 410 420 ANKLGVQMGH APITSVSYLR IYYALFRNLA KEIGGDFFKF YQQLIKLEEL ENRLEILMCD 430 440 450 460 470 480 VKTTVITPST LALVLICLHL DFHIKESYTR GSPELKHVFE YILFLQQYMR IPDRVFTCGF 490 500 510 520 530 540 SIVSGILSHY NGQNKAPYKQ RLVWKLSSRT LRVLRPINRF SSDLPTIEEG IPNALDDGLR 550 560 SRTESISSEE EEDWPTSPII PIFEQC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Release 5.1 annotation of Drosophila melanogaster heterochromatin." Smith C.D., Shu S., Mungall C.J., Karpen G.H. Science 316:1586-1591(2007) [PubMed: 17569856] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Sequence finishing and mapping of Drosophila melanogaster heterochromatin." Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., Dimitri P., Karpen G.H., Celniker S.E. Science 316:1625-1628(2007) [PubMed: 17569867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Combined evidence annotation of transposable elements in genome sequences." Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D. PLoS Comput. Biol. 1:166-175(2005) [PubMed: 16110336] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[6]	"Heterochromatic sequences in a Drosophila whole-genome shotgun assembly." Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H. Genome Biol. 3:RESEARCH0085.1-RESEARCH0085.16(2002) [PubMed: 12537574] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[7]	"The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective." Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J.W., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E. Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed: 12537573] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[8]	"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence." Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., Pacleb J.M., Park S. , Pfeiffer B.D., Richards S., Sodergren E.J., Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M. Genome Biol. 3 (12), RESEARCH0079 (2002) Cited for: NUCLEOTIDE SEQUENCE.
[9]	Drosophila Heterochromatin Genome Project Smith C.D., Shu S., Mungall C.J., Karpen G.H. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[10]	FlyBase Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[11]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL13949.1.
[12]	"Drosophila melanogaster release 4 sequence." Berkeley Drosophila Genome Project Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[13]	Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Karpen G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[14]	Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G. Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF57168.2. AE014297 Genomic DNA. Translation: AAF57169.2. AE014297 Genomic DNA. Translation: AAF57170.2. AE014297 Genomic DNA. Translation: AAF57171.2. AY058720 mRNA. Translation: AAL13949.1.
RefSeq	NP_524609.2. NM_079870.2. NP_733434.1. NM_170555.1. NP_733435.1. NM_170556.1. NP_733436.1. NM_170557.1.
UniGene	Dm.1390.
3D structure databases
ProteinModelPortal	Q95TJ9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q95TJ9. 52 interactions.
STRING	Q95TJ9.
Proteomic databases
PRIDE	Q95TJ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0085799; FBpp0085160; FBgn0039858. FBtr0085800; FBpp0085161; FBgn0039858. FBtr0085802; FBpp0085163; FBgn0039858. FBtr0085803; FBpp0085164; FBgn0039858.
GeneID	43724.
KEGG	dme:Dmel_CG11525.
UCSC	CG11525-RA. d. melanogaster.
Organism-specific databases
CTD	43724.
FlyBase	FBgn0039858. CycG.
Phylogenomic databases
GeneTree	EMGT00050000009563.
InParanoid	Q95TJ9.
OMA	DFHIKES.
PhylomeDB	Q95TJ9.
Gene expression databases
ArrayExpress	Q95TJ9.
Bgee	Q95TJ9.
Family and domain databases
InterPro	IPR013763. Cyclin-like. IPR006671. Cyclin_N. [Graphical view]
Gene3D	G3DSA:1.10.472.10. Cyclin_related. 1 hit.
Pfam	PF00134. Cyclin_N. 1 hit. [Graphical view]
SMART	SM00385. CYCLIN. 1 hit. [Graphical view]
SUPFAM	SSF47954. Cyclin_like. 1 hit.
ProtoNet	Search...
Other
NextBio	835445.

Entry information

Entry name

Q95TJ9_DROME

Accession

Primary (citable) accession number: Q95TJ9

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)