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Protein

Palmitoyltransferase

Gene

CG5880

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG5880Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0039489. CG5880.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei62 – 84HelicalUniRule annotationAdd BLAST23
Transmembranei96 – 117HelicalUniRule annotationAdd BLAST22
Transmembranei182 – 201HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

  • Golgi apparatus Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ95S28.
PRIDEiQ95S28.

Expressioni

Gene expression databases

BgeeiFBgn0039489.
ExpressionAtlasiQ95S28. differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 203DHHCInterPro annotationAdd BLAST67

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1313. Eukaryota.
COG5273. LUCA.
OrthoDBiEOG091G0FLT.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q95S28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARITWRGHS TQELLSILRL RWSYMKHCWH SLTFNAHMNS SYASDVCLTP
60 70 80 90 100
IFWFVDNYTH CLGPFFVVGV AALTTSVVSI AYWIGLPFWW AKSQLVTYFL
110 120 130 140 150
LIVGNWLLLN VVFHYVMAVI TPAGHPPEGV SLVEAVSMCG KCIAPKPPRT
160 170 180 190 200
HHCSICNRCI LKMDHHCPWL NNCVGYGNHR YFFLYMTYTT LGCLFLILFG
210 220 230
LEIGHKYLWL DHGENWTEIE PWRGSQSSLT SVDTSFQ
Length:237
Mass (Da):27,287
Last modified:December 1, 2001 - v1
Checksum:i3CC6F741306507B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY060980 mRNA. Translation: AAL28528.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ95S28_DROME
AccessioniPrimary (citable) accession number: Q95S28
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 5, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)