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Protein

Palmitoyltransferase

Gene

CG5880

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG5880Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0039489. CG5880.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei62 – 84HelicalUniRule annotationAdd BLAST23
Transmembranei96 – 117HelicalUniRule annotationAdd BLAST22
Transmembranei182 – 201HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ95S28.
PRIDEiQ95S28.

Expressioni

Gene expression databases

BgeeiFBgn0039489.
ExpressionAtlasiQ95S28. differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 203DHHCInterPro annotationAdd BLAST67

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1313. Eukaryota.
COG5273. LUCA.
OrthoDBiEOG091G0FLT.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q95S28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARITWRGHS TQELLSILRL RWSYMKHCWH SLTFNAHMNS SYASDVCLTP
60 70 80 90 100
IFWFVDNYTH CLGPFFVVGV AALTTSVVSI AYWIGLPFWW AKSQLVTYFL
110 120 130 140 150
LIVGNWLLLN VVFHYVMAVI TPAGHPPEGV SLVEAVSMCG KCIAPKPPRT
160 170 180 190 200
HHCSICNRCI LKMDHHCPWL NNCVGYGNHR YFFLYMTYTT LGCLFLILFG
210 220 230
LEIGHKYLWL DHGENWTEIE PWRGSQSSLT SVDTSFQ
Length:237
Mass (Da):27,287
Last modified:December 1, 2001 - v1
Checksum:i3CC6F741306507B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY060980 mRNA. Translation: AAL28528.1.

Entry informationi

Entry nameiQ95S28_DROME
AccessioniPrimary (citable) accession number: Q95S28
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 25, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)