Reviewed, UniProtKB/Swiss-Prot Q95QQ2 (U533_CAEEL)

Names and origin

Protein names

Recommended name:
    UPF0533 protein C56C10.7

Gene names

ORF Names:

C56C10.7

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0533 family.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	Q9N3Y1	1	EBI-316807,EBI-315848
sdz-38	Q09620	1	EBI-316807,EBI-332504

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform a (identifier: Q95QQ2-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform b (identifier: Q95QQ2-2)

The sequence of this isoform differs from the canonical sequence as follows:
     184-225: DNANQDVYLE...HYNVTSIAHE → VSSNRVLCIN...IMLLVSLMST

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 401	401	UPF0533 protein C56C10.7		PRO_0000321555
Natural variations
	Alternative sequence	184 – 225	42	DNANQ…SIAHE → VSSNRVLCINVVFFRTMRIK MSTSKPKLKIHQMRICSWKK SSWIQVNIIMLLVSLMST in isoform b.		VSP_031802

Sequences

	Sequence		Length	Mass (Da)
	Isoform a [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 67024AD4CEA27998	FASTA	401	44,844
	10 20 30 40 50 60 MADNPASSSS QQLLALRVMR LARPKFAPVD GFSHDPVDPT GFGELLAGKV SEISKESRQD 70 80 90 100 110 120 LPIGEYLIAP QMFENIYLGE TFTFYVNVVN ESEKTVSSVS LKCELQTSTQ RVVLPCSVQD 130 140 150 160 170 180 ATIESSKCEG QVISHEVKEI GQHILICSVN YKTSNGENMY FRKFFKFPVS KPIDVKTKFY 190 200 210 220 230 240 SAEDNANQDV YLEAQIENTS NANMFLEKVE LDPSQHYNVT SIAHEDEFGD VGKLLKPKDI 250 260 270 280 290 300 RQFLFCLTPA DVHNTLGYKD LTSIGKLDMS WRTSMGEKGR LQTSALQRIA PGYGDVRLSV 310 320 330 340 350 360 EKTPACVDVQ KPFEVSCRLY NCSERALDLQ LRLEQPSNRH LVFCSPSGVS LGQLPPSQHV 370 380 390 400 DFSLNVFPVT VGIQSISGIR ITDTFTKRIY EHDDIAQIFV S
	Isoform b. Checksum: CD88A2F959F42A55	FASTA	417	46,864
	10 20 30 40 50 60 MADNPASSSS QQLLALRVMR LARPKFAPVD GFSHDPVDPT GFGELLAGKV SEISKESRQD 70 80 90 100 110 120 LPIGEYLIAP QMFENIYLGE TFTFYVNVVN ESEKTVSSVS LKCELQTSTQ RVVLPCSVQD 130 140 150 160 170 180 ATIESSKCEG QVISHEVKEI GQHILICSVN YKTSNGENMY FRKFFKFPVS KPIDVKTKFY 190 200 210 220 230 240 SAEVSSNRVL CINVVFFRTM RIKMSTSKPK LKIHQMRICS WKKSSWIQVN IIMLLVSLMS 250 260 270 280 290 300 TDEFGDVGKL LKPKDIRQFL FCLTPADVHN TLGYKDLTSI GKLDMSWRTS MGEKGRLQTS 310 320 330 340 350 360 ALQRIAPGYG DVRLSVEKTP ACVDVQKPFE VSCRLYNCSE RALDLQLRLE QPSNRHLVFC 370 380 390 400 410 SPSGVSLGQL PPSQHVDFSL NVFPVTVGIQ SISGIRITDT FTKRIYEHDD IAQIFVS

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U29488 Genomic DNA. Translation: AAL27235.1. U29488 Genomic DNA. Translation: AAL27236.1.
RefSeq	NP_741009.1.
UniGene	Cel.15611
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:24418N.
IntAct	Q95QQ2. 3 interactions.
Proteomic databases
PRIDE	Q95QQ2.
Genome annotation databases
Ensembl	C56C10.7. Caenorhabditis elegans. [Contig view]
GeneID	174089.
Organism-specific databases
WormBase	WBGene00016964. C56C10.7.
WormPep	C56C10.7a. CE29739. [WorfDB] C56C10.7b. CE29740. [WorfDB]
Phylogenomic databases
OMA	Q95QQ2. FYNAESD.
Gene expression databases
ArrayExpress	Q95QQ2.
Family and domain databases
InterPro	IPR010378. DUF974. [Graphical view]
PANTHER	PTHR13134. DUF974. 1 hit.
Pfam	PF06159. DUF974. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	882457.

Entry information

Entry name

U533_CAEEL

Accession

Primary (citable) accession number: Q95QQ2
Secondary accession number(s): Q95QQ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 1, 2001
Last modified:	June 16, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project