Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q95Q25 (Q95Q25_CAEEL) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:rad-51 EMBL CAB61038.2 WormBase Y43C5A.6a
ORF Names:CELE_Y43C5A.6 EMBL CAB61038.2, Y43C5A.6 WormBase Y43C5A.6a
OrganismCaenorhabditis elegans [Reference proteome] EMBL CAB61038.2
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the RecA family. RuleBase RU003422

Ontologies

Keywords
   LigandATP-binding RuleBase RU003422
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processATP catabolic process

Inferred from direct assay PubMed 17483448. Source: WormBase

DNA recombination

Inferred from direct assay PubMed 16843491. Source: GOC

DNA repair

Inferred from electronic annotation. Source: InterPro

cellular response to DNA damage stimulus

Inferred from mutant phenotype PubMed 12684824. Source: WormBase

embryo development ending in birth or egg hatching

Inferred from mutant phenotype PubMed 12684824. Source: WormBase

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Inferred from genetic interaction PubMed 12684824. Source: WormBase

meiotic chromosome condensation

Inferred from mutant phenotype PubMed 12684824. Source: WormBase

negative regulation of apoptotic process

Inferred from mutant phenotype PubMed 12684824. Source: WormBase

   Cellular_componentcondensed nuclear chromosome

Inferred from direct assay PubMed 12684824. Source: WormBase

germ cell nucleus

Inferred from direct assay PubMed 12684824PubMed 18007596. Source: WormBase

nucleus

Inferred from direct assay PubMed 12684824. Source: WormBase

site of double-strand break

Inferred from direct assay PubMed 17983271. Source: WormBase

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from direct assay PubMed 16843491. Source: WormBase

DEAD/H-box RNA helicase binding

Inferred from physical interaction PubMed 20122407. Source: WormBase

DNA-dependent ATPase activity

Inferred from direct assay PubMed 17483448. Source: WormBase

damaged DNA binding

Inferred from electronic annotation. Source: InterPro

double-stranded DNA binding

Inferred from direct assay PubMed 20122407. Source: WormBase

identical protein binding

Inferred from physical interaction PubMed 11731503PubMed 11778048PubMed 14704431PubMed 14711411PubMed 19123269. Source: IntAct

protein binding

Inferred from physical interaction PubMed 11731503PubMed 11778048PubMed 14711411PubMed 19123269. Source: IntAct

recombinase activity

Inferred from direct assay PubMed 16843491. Source: WormBase

Complete GO annotation...

Binary interactions

Sequences

Sequence LengthMass (Da)Tools
Q95Q25 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: E844516B0C1A6AF8

FASTA39543,625
        10         20         30         40         50         60 
MGQSWGYEGI AKRSLCTHKW LYNLNLHSIN LFLPIESKMS AQASRQKKSD QEQRAADQAL 

        70         80         90        100        110        120 
LNAAIEDNAM EQDENFTVID KLESSGISSG DISKLKEAGY YTYESLAFTT RRELRNVKGI 

       130        140        150        160        170        180 
SDQKAEKIMK EAMKFVQMGF TTGAEVHVKR SQLVQIRTGS ASLDRLLGGG IETGSITEVY 

       190        200        210        220        230        240 
GEYRTGKTQL CHSLAVLCQL PIDMGGGEGK CMYIDTNATF RPERIIAIAQ RYNMDSAHVL 

       250        260        270        280        290        300 
ENIAVARAYN SEHLMALIIR AGAMMSESRY AVVIVDCATA HFRNEYTGRG DLAERQMKLS 

       310        320        330        340        350        360 
AFLKCLAKLA DEYGVAVIIT NQVVAQVDGG ASMFQADAKK PIGGHIIAHM STTRLYLRKG 

       370        380        390 
KGENRVAKMV QSPNLPEAEA TYSITNHGIE DARED 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL023838 Genomic DNA. Translation: CAB61038.2.
RefSeqNP_001023465.1. NM_001028294.2.
UniGeneCel.19596.

3D structure databases

ProteinModelPortalQ95Q25.
SMRQ95Q25. Positions 79-394.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-25225N.
IntActQ95Q25. 10 interactions.
MINTMINT-226974.
STRING6239.Y43C5A.6a.

Proteomic databases

PRIDEQ95Q25.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaY43C5A.6a; Y43C5A.6a; WBGene00004297.
GeneID177914.
KEGGcel:CELE_Y43C5A.6.
UCSCY43C5A.6b. c. elegans.

Organism-specific databases

CTD177914.
WormBaseY43C5A.6a; CE29064; WBGene00004297; rad-51.

Phylogenomic databases

GeneTreeENSGT00750000117750.
HOGENOMHOG000227426.
InParanoidQ95Q25.
KOK04482.
OMAMMAESRY.
OrthoDBEOG715Q4H.
PhylomeDBQ95Q25.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR011941. DNA_recomb/repair_Rad51.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFPIRSF005856. Rad51. 1 hit.
SMARTSM00382. AAA. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view]
SUPFAMSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR02239. recomb_RAD51. 1 hit.
PROSITEPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio898916.
PROQ95Q25.

Entry information

Entry nameQ95Q25_CAEEL
AccessionPrimary (citable) accession number: Q95Q25
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)