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Q95Q25

- Q95Q25_CAEEL

UniProt

Q95Q25 - Q95Q25_CAEEL

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Protein
Submitted name:

Protein RAD-51, isoform a

Gene

rad-51

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATPase activity Source: WormBase
  2. ATP binding Source: UniProtKB-KW
  3. damaged DNA binding Source: InterPro
  4. DEAD/H-box RNA helicase binding Source: WormBase
  5. DNA-dependent ATPase activity Source: WormBase
  6. double-stranded DNA binding Source: WormBase
  7. identical protein binding Source: IntAct
  8. recombinase activity Source: WormBase

GO - Biological processi

  1. ATP catabolic process Source: WormBase
  2. cellular response to DNA damage stimulus Source: WormBase
  3. DNA recombination Source: GOC
  4. DNA repair Source: InterPro
  5. embryo development ending in birth or egg hatching Source: WormBase
  6. intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Source: WormBase
  7. meiotic chromosome condensation Source: WormBase
  8. negative regulation of apoptotic process Source: WormBase
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Protein RAD-51, isoform aImported
Gene namesi
Name:rad-51Imported
ORF Names:CELE_Y43C5A.6Imported, Y43C5A.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiY43C5A.6a; CE29064; WBGene00004297; rad-51.

Subcellular locationi

GO - Cellular componenti

  1. condensed nuclear chromosome Source: WormBase
  2. germ cell nucleus Source: WormBase
  3. nucleus Source: WormBase
  4. site of double-strand break Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ95Q25.

Expressioni

Gene expression databases

ExpressionAtlasiQ95Q25. baseline.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself6EBI-321895,EBI-321895
rfs-1P343483EBI-321895,EBI-330791
ubc-9Q950174EBI-321895,EBI-328938

Protein-protein interaction databases

DIPiDIP-25225N.
IntActiQ95Q25. 10 interactions.
MINTiMINT-226974.
STRINGi6239.Y43C5A.6a.

Structurei

3D structure databases

ProteinModelPortaliQ95Q25.
SMRiQ95Q25. Positions 79-394.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00750000117750.
HOGENOMiHOG000227426.
InParanoidiQ95Q25.
KOiK04482.
OMAiMMAESRY.
OrthoDBiEOG715Q4H.
PhylomeDBiQ95Q25.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011941. DNA_recomb/repair_Rad51.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view]
SUPFAMiSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02239. recomb_RAD51. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q95Q25-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGQSWGYEGI AKRSLCTHKW LYNLNLHSIN LFLPIESKMS AQASRQKKSD
60 70 80 90 100
QEQRAADQAL LNAAIEDNAM EQDENFTVID KLESSGISSG DISKLKEAGY
110 120 130 140 150
YTYESLAFTT RRELRNVKGI SDQKAEKIMK EAMKFVQMGF TTGAEVHVKR
160 170 180 190 200
SQLVQIRTGS ASLDRLLGGG IETGSITEVY GEYRTGKTQL CHSLAVLCQL
210 220 230 240 250
PIDMGGGEGK CMYIDTNATF RPERIIAIAQ RYNMDSAHVL ENIAVARAYN
260 270 280 290 300
SEHLMALIIR AGAMMSESRY AVVIVDCATA HFRNEYTGRG DLAERQMKLS
310 320 330 340 350
AFLKCLAKLA DEYGVAVIIT NQVVAQVDGG ASMFQADAKK PIGGHIIAHM
360 370 380 390
STTRLYLRKG KGENRVAKMV QSPNLPEAEA TYSITNHGIE DARED
Length:395
Mass (Da):43,625
Last modified:December 1, 2001 - v1
Checksum:iE844516B0C1A6AF8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL023838 Genomic DNA. Translation: CAB61038.2.
RefSeqiNP_001023465.1. NM_001028294.2.
UniGeneiCel.19596.

Genome annotation databases

EnsemblMetazoaiY43C5A.6a; Y43C5A.6a; WBGene00004297.
GeneIDi177914.
KEGGicel:CELE_Y43C5A.6.
UCSCiY43C5A.6b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL023838 Genomic DNA. Translation: CAB61038.2 .
RefSeqi NP_001023465.1. NM_001028294.2.
UniGenei Cel.19596.

3D structure databases

ProteinModelPortali Q95Q25.
SMRi Q95Q25. Positions 79-394.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-25225N.
IntActi Q95Q25. 10 interactions.
MINTi MINT-226974.
STRINGi 6239.Y43C5A.6a.

Proteomic databases

PRIDEi Q95Q25.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y43C5A.6a ; Y43C5A.6a ; WBGene00004297 .
GeneIDi 177914.
KEGGi cel:CELE_Y43C5A.6.
UCSCi Y43C5A.6b. c. elegans.

Organism-specific databases

CTDi 177914.
WormBasei Y43C5A.6a ; CE29064 ; WBGene00004297 ; rad-51.

Phylogenomic databases

GeneTreei ENSGT00750000117750.
HOGENOMi HOG000227426.
InParanoidi Q95Q25.
KOi K04482.
OMAi MMAESRY.
OrthoDBi EOG715Q4H.
PhylomeDBi Q95Q25.

Miscellaneous databases

NextBioi 898916.
PROi Q95Q25.

Gene expression databases

ExpressionAtlasi Q95Q25. baseline.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR011941. DNA_recomb/repair_Rad51.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view ]
Pfami PF08423. Rad51. 1 hit.
[Graphical view ]
PIRSFi PIRSF005856. Rad51. 1 hit.
SMARTi SM00382. AAA. 1 hit.
SM00278. HhH1. 1 hit.
[Graphical view ]
SUPFAMi SSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR02239. recomb_RAD51. 1 hit.
PROSITEi PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ95Q25_CAEEL
AccessioniPrimary (citable) accession number: Q95Q25
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3