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Q95Q25

- Q95Q25_CAEEL

UniProt

Q95Q25 - Q95Q25_CAEEL

Protein
Submitted name:

Protein RAD-51, isoform a

Gene

rad-51

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 109 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATPase activity Source: WormBase
    2. ATP binding Source: UniProtKB-KW
    3. damaged DNA binding Source: InterPro
    4. DEAD/H-box RNA helicase binding Source: WormBase
    5. DNA-dependent ATPase activity Source: WormBase
    6. double-stranded DNA binding Source: WormBase
    7. identical protein binding Source: IntAct
    8. protein binding Source: IntAct
    9. recombinase activity Source: WormBase

    GO - Biological processi

    1. ATP catabolic process Source: WormBase
    2. cellular response to DNA damage stimulus Source: WormBase
    3. DNA recombination Source: GOC
    4. DNA repair Source: InterPro
    5. embryo development ending in birth or egg hatching Source: WormBase
    6. intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Source: WormBase
    7. meiotic chromosome condensation Source: WormBase
    8. negative regulation of apoptotic process Source: WormBase

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein RAD-51, isoform aImported
    Gene namesi
    Name:rad-51Imported
    ORF Names:CELE_Y43C5A.6Imported, Y43C5A.6Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome IV

    Organism-specific databases

    WormBaseiY43C5A.6a; CE29064; WBGene00004297; rad-51.

    Subcellular locationi

    GO - Cellular componenti

    1. condensed nuclear chromosome Source: WormBase
    2. germ cell nucleus Source: WormBase
    3. nucleus Source: WormBase
    4. site of double-strand break Source: WormBase

    PTM / Processingi

    Proteomic databases

    PRIDEiQ95Q25.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself6EBI-321895,EBI-321895
    rfs-1P343483EBI-321895,EBI-330791
    ubc-9Q950174EBI-321895,EBI-328938

    Protein-protein interaction databases

    DIPiDIP-25225N.
    IntActiQ95Q25. 10 interactions.
    MINTiMINT-226974.
    STRINGi6239.Y43C5A.6a.

    Structurei

    3D structure databases

    ProteinModelPortaliQ95Q25.
    SMRiQ95Q25. Positions 79-394.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RecA family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117750.
    HOGENOMiHOG000227426.
    InParanoidiQ95Q25.
    KOiK04482.
    OMAiMMAESRY.
    OrthoDBiEOG715Q4H.
    PhylomeDBiQ95Q25.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR011941. DNA_recomb/repair_Rad51.
    IPR013632. DNA_recomb/repair_Rad51_C.
    IPR016467. DNA_recomb/repair_RecA-like.
    IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR027417. P-loop_NTPase.
    IPR020588. RecA_ATP-bd.
    IPR020587. RecA_monomer-monomer_interface.
    [Graphical view]
    PfamiPF08423. Rad51. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005856. Rad51. 1 hit.
    SMARTiSM00382. AAA. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view]
    SUPFAMiSSF47794. SSF47794. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR02239. recomb_RAD51. 1 hit.
    PROSITEiPS50162. RECA_2. 1 hit.
    PS50163. RECA_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q95Q25-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQSWGYEGI AKRSLCTHKW LYNLNLHSIN LFLPIESKMS AQASRQKKSD    50
    QEQRAADQAL LNAAIEDNAM EQDENFTVID KLESSGISSG DISKLKEAGY 100
    YTYESLAFTT RRELRNVKGI SDQKAEKIMK EAMKFVQMGF TTGAEVHVKR 150
    SQLVQIRTGS ASLDRLLGGG IETGSITEVY GEYRTGKTQL CHSLAVLCQL 200
    PIDMGGGEGK CMYIDTNATF RPERIIAIAQ RYNMDSAHVL ENIAVARAYN 250
    SEHLMALIIR AGAMMSESRY AVVIVDCATA HFRNEYTGRG DLAERQMKLS 300
    AFLKCLAKLA DEYGVAVIIT NQVVAQVDGG ASMFQADAKK PIGGHIIAHM 350
    STTRLYLRKG KGENRVAKMV QSPNLPEAEA TYSITNHGIE DARED 395
    Length:395
    Mass (Da):43,625
    Last modified:December 1, 2001 - v1
    Checksum:iE844516B0C1A6AF8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL023838 Genomic DNA. Translation: CAB61038.2.
    RefSeqiNP_001023465.1. NM_001028294.2.
    UniGeneiCel.19596.

    Genome annotation databases

    EnsemblMetazoaiY43C5A.6a; Y43C5A.6a; WBGene00004297.
    GeneIDi177914.
    KEGGicel:CELE_Y43C5A.6.
    UCSCiY43C5A.6b. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL023838 Genomic DNA. Translation: CAB61038.2 .
    RefSeqi NP_001023465.1. NM_001028294.2.
    UniGenei Cel.19596.

    3D structure databases

    ProteinModelPortali Q95Q25.
    SMRi Q95Q25. Positions 79-394.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-25225N.
    IntActi Q95Q25. 10 interactions.
    MINTi MINT-226974.
    STRINGi 6239.Y43C5A.6a.

    Proteomic databases

    PRIDEi Q95Q25.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Y43C5A.6a ; Y43C5A.6a ; WBGene00004297 .
    GeneIDi 177914.
    KEGGi cel:CELE_Y43C5A.6.
    UCSCi Y43C5A.6b. c. elegans.

    Organism-specific databases

    CTDi 177914.
    WormBasei Y43C5A.6a ; CE29064 ; WBGene00004297 ; rad-51.

    Phylogenomic databases

    GeneTreei ENSGT00750000117750.
    HOGENOMi HOG000227426.
    InParanoidi Q95Q25.
    KOi K04482.
    OMAi MMAESRY.
    OrthoDBi EOG715Q4H.
    PhylomeDBi Q95Q25.

    Miscellaneous databases

    NextBioi 898916.
    PROi Q95Q25.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR011941. DNA_recomb/repair_Rad51.
    IPR013632. DNA_recomb/repair_Rad51_C.
    IPR016467. DNA_recomb/repair_RecA-like.
    IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR027417. P-loop_NTPase.
    IPR020588. RecA_ATP-bd.
    IPR020587. RecA_monomer-monomer_interface.
    [Graphical view ]
    Pfami PF08423. Rad51. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005856. Rad51. 1 hit.
    SMARTi SM00382. AAA. 1 hit.
    SM00278. HhH1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47794. SSF47794. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR02239. recomb_RAD51. 1 hit.
    PROSITEi PS50162. RECA_2. 1 hit.
    PS50163. RECA_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ95Q25_CAEEL
    AccessioniPrimary (citable) accession number: Q95Q25
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 1, 2001
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 109 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3