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Protein
Submitted name:

Prostaglandin E2 subtype EP4 receptor

Gene
N/A
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin E2 subtype EP4 receptorImported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4222HelicalSequence analysisAdd
BLAST
Transmembranei54 – 7724HelicalSequence analysisAdd
BLAST
Transmembranei97 – 11519HelicalSequence analysisAdd
BLAST
Transmembranei135 – 15622HelicalSequence analysisAdd
BLAST
Transmembranei186 – 21126HelicalSequence analysisAdd
BLAST
Transmembranei273 – 29624HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ95J39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 331298G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG053556.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001758. Prost_EP4_rcpt.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 2 hits.
PTHR11866:SF6. PTHR11866:SF6. 2 hits.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00586. PRSTNOIDEP4R.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q95J39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPGVNAST SLSPDRLNSP VTIPAVMFIF GVVGNLVAIV VLCKSRKEQK
60 70 80 90 100
ETTFYTLVCG LAVTDLLGTL LVSPVTIATY MKGQWPGGQP LCEYSTFILL
110 120 130 140 150
FFSLSGLSII CAMSVERYLA INHAYFYSHY VDKRLAGLTL FAVYASNVLF
160 170 180 190 200
CALPNMGLGS SRLQYPDTWC FIDWTTNVTA HAAYSYMYAG FSSFLILATV
210 220 230 240 250
LCNVLVCGAL LRMHRQFMRR TSLGTEQHHA AATAVTSVVS RGHPAASPGL
260 270 280 290 300
PRLSDFRRRR SFRRIAGAEI QMVILLIATS LVVLICSIPL VVRVFVNQLY
310 320 330 340 350
QPSLEREVSK NPDLQAIRIA SVNPILDPWI YILLRKTVLS KAIEKIKCLF
360 370 380 390 400
CRIGGSRRER SGQHCSDSRR TSSAMSGHSR SFFSRELKEI SSTSQTLLPD
410 420 430 440 450
LSLPDLSENG LGGRNLLPGV PGMGLAQKDT TSLRTLRISE TSDSSQGQDS
460 470 480 490
ESVLLVDEVG GSGRAGPAPK GSSLQVTFPS ETLNLSEKCI
Length:490
Mass (Da):53,467
Last modified:December 1, 2001 - v1
Checksum:i72F3C1B0A89C02F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY052643 mRNA. Translation: AAL15041.1.
RefSeqiXP_005556840.1. XM_005556783.2.
UniGeneiMfa.6114.

Genome annotation databases

GeneIDi101865027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY052643 mRNA. Translation: AAL15041.1.
RefSeqiXP_005556840.1. XM_005556783.2.
UniGeneiMfa.6114.

3D structure databases

ProteinModelPortaliQ95J39.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101865027.

Organism-specific databases

CTDi5734.

Phylogenomic databases

HOVERGENiHBG053556.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001758. Prost_EP4_rcpt.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 2 hits.
PTHR11866:SF6. PTHR11866:SF6. 2 hits.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00586. PRSTNOIDEP4R.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Macaca fascicularis prostaglandin E2 subtype EP4 receptor."
    Smock S.L., Castleberry T.A., Lu B., Owen T.A.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ95J39_MACFA
AccessioniPrimary (citable) accession number: Q95J39
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 13, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.