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Protein
Submitted name:

Prostaglandin E2 subtype EP4 receptor

Gene
N/A
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin E2 subtype EP4 receptorImported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 42HelicalSequence analysisAdd BLAST22
Transmembranei54 – 77HelicalSequence analysisAdd BLAST24
Transmembranei97 – 115HelicalSequence analysisAdd BLAST19
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei186 – 211HelicalSequence analysisAdd BLAST26
Transmembranei273 – 296HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ95J39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 331G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST298

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG053556.

Family and domain databases

CDDicd15142. 7tmA_PGE2_EP4. 1 hit.
InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001758. Prost_EP4_rcpt.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
PANTHERiPTHR11866. PTHR11866. 1 hit.
PTHR11866:SF24. PTHR11866:SF24. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00586. PRSTNOIDEP4R.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q95J39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTPGVNAST SLSPDRLNSP VTIPAVMFIF GVVGNLVAIV VLCKSRKEQK
60 70 80 90 100
ETTFYTLVCG LAVTDLLGTL LVSPVTIATY MKGQWPGGQP LCEYSTFILL
110 120 130 140 150
FFSLSGLSII CAMSVERYLA INHAYFYSHY VDKRLAGLTL FAVYASNVLF
160 170 180 190 200
CALPNMGLGS SRLQYPDTWC FIDWTTNVTA HAAYSYMYAG FSSFLILATV
210 220 230 240 250
LCNVLVCGAL LRMHRQFMRR TSLGTEQHHA AATAVTSVVS RGHPAASPGL
260 270 280 290 300
PRLSDFRRRR SFRRIAGAEI QMVILLIATS LVVLICSIPL VVRVFVNQLY
310 320 330 340 350
QPSLEREVSK NPDLQAIRIA SVNPILDPWI YILLRKTVLS KAIEKIKCLF
360 370 380 390 400
CRIGGSRRER SGQHCSDSRR TSSAMSGHSR SFFSRELKEI SSTSQTLLPD
410 420 430 440 450
LSLPDLSENG LGGRNLLPGV PGMGLAQKDT TSLRTLRISE TSDSSQGQDS
460 470 480 490
ESVLLVDEVG GSGRAGPAPK GSSLQVTFPS ETLNLSEKCI
Length:490
Mass (Da):53,467
Last modified:December 1, 2001 - v1
Checksum:i72F3C1B0A89C02F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY052643 mRNA. Translation: AAL15041.1.
RefSeqiXP_005556840.1. XM_005556783.2.
UniGeneiMfa.6114.

Genome annotation databases

GeneIDi101865027.

Similar proteinsi

Entry informationi

Entry nameiQ95J39_MACFA
AccessioniPrimary (citable) accession number: Q95J39
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: August 30, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)