Q95J07 (Q95J07_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MHC class I antigen heavy chain EMBL AAD39980.1

Gene names

Name:

HLA-A EMBL AAD39980.1

Organism

Homo sapiens (Human) EMBL AAD39980.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the presentation of foreign antigens to the immune system By similarity. SAAS SAAS003006
Sequence similarities	Belongs to the MHC class I family. RuleBase RU004439 Contains 1 Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS003006

Ontologies

Keywords
Biological process	Immunity
Cellular component	MHC I SAAS SAAS003006 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS003006
PTM	Disulfide bond SAAS SAAS003006
Gene Ontology (GO)
Biological_process	antigen processing and presentation of peptide antigen via MHC class I Inferred from electronic annotation. Source: UniProtKB-KW immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	MHC class I protein complex Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q95J07 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 7E5D1A03C04BEA83	FASTA	365	40,904
	10 20 30 40 50 60 MAVMAPRTLL LLLSGALALT QTWAGSHSMR YFSTSVSRPG SGEPRFIAVG YVDDTQFVRF 70 80 90 100 110 120 DSDAASQRME PRAPWIEQER PEYWDQETRN VKAHSQTDRE NLGTLRGYYN QSEAGSHTIQ 130 140 150 160 170 180 IMYGCDVGSD GRFLRGYEQH AYDGKDYIAL NEDLRSWTAA DMAAQITQRK WEAARRAEQL 190 200 210 220 230 240 RAYLEGTCVE WLRRYLENGK ETLQRTDPPK THMTHHPISD HEATLRCWAL GFYPAEITLT 250 260 270 280 290 300 WQRDGEDQTQ DTELVETRPA GDGTFQKWAA VVVPSGEEQR YTCHVQHEGL PKPLTLRWEL 310 320 330 340 350 360 SSQPTIPIVG IIAGLVLLGA VITGAVVAAV MWRRKSSDRK GGSYTQAASS DSAQGSDVSL TACKV

References

[1]	"A New HLA-A*30 genomic sequence." Bettinotti M.P., Dhillon G., Hackett J., Simonis T.B., Marincola F.M. Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF148862 Genomic DNA. Translation: AAD39980.1.
IPI	IPI00647634.
PIR	I37476. S52290.
UniGene	Hs.181244. Hs.713441.
3D structure databases
ProteinModelPortal	Q95J07.
SMR	Q95J07. Positions 25-299.
ModBase	Search...
Proteomic databases
PRIDE	Q95J07.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG016709.
Gene expression databases
Bgee	Q95J07.
Family and domain databases
Gene3D	2.60.40.10. 1 hit. 3.30.500.10. 1 hit.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR003006. Ig/MHC_CS. IPR003597. Ig_C1-set. IPR011161. MHC_I-like_Ag-recog. IPR011162. MHC_I/II-like_Ag-recog. IPR001039. MHC_I_a_a1/a2. IPR010579. MHC_I_a_C. [Graphical view]
Pfam	PF07654. C1-set. 1 hit. PF00129. MHC_I. 1 hit. PF06623. MHC_I_C. 1 hit. [Graphical view]
PRINTS	PR01638. MHCCLASSI.
SMART	SM00407. IGc1. 1 hit. [Graphical view]
SUPFAM	SSF54452. MHC_I/II-like_Ag-recog. 1 hit.
PROSITE	PS50835. IG_LIKE. 1 hit. PS00290. IG_MHC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	HLA-A. human.

Entry information

Entry name

Q95J07_HUMAN

Accession

Primary (citable) accession number: Q95J07

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 29, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.