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Q95914

- COX3_POLOR

UniProt

Q95914 - COX3_POLOR

Protein

Cytochrome c oxidase subunit 3

Gene

mt-co3

Organism
Polypterus ornatipinnis (Ornate bichir)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:mt-co3
    Synonyms:coiii, coxiii, mtco3
    Encoded oniMitochondrion
    OrganismiPolypterus ornatipinnis (Ornate bichir)
    Taxonomic identifieri49895 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiPolypteriformesPolypteridaePolypterus

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell
    3. respiratory chain complex IV Source: UniProtKB

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 261261Cytochrome c oxidase subunit 3PRO_0000183836Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ95914.
    SMRiQ95914. Positions 1-261.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei31 – 5121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei81 – 10121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei126 – 14621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei162 – 18221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei197 – 21721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei239 – 25921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOVERGENiHBG016686.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q95914-1 [UniParc]FASTAAdd to Basket

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    MAHQAHAYHM VDPSPWPLTG AVAALLLTSG LAVWFHFKSL TLLAMGLLLM    50
    ILTMIQWWRD IIREGTFQGH HTPPVQKGLR YGMILFITSE VFFFLGFFWA 100
    FYHSSLAPTP ELGGIWPPTG ITPLDPFEVP LLNTAVLLAS GVTVTWTHHS 150
    LMEGKRTEAT QALTLTILLG LYFTALQAME YYEAPFTIAD GVYGTTFFVA 200
    TGFHGLHVII GSTFLAGCLL RQILYHFTSS HHFGFEAAAW YWHFVDVVWL 250
    FLYVSIYWWG S 261
    Length:261
    Mass (Da):29,465
    Last modified:February 1, 1997 - v1
    Checksum:iD9323EF58F81246B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U62532 Genomic DNA. Translation: AAC60311.1.
    PIRiT11460.
    RefSeqiNP_008322.1. NC_001778.1.

    Genome annotation databases

    GeneIDi808029.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U62532 Genomic DNA. Translation: AAC60311.1 .
    PIRi T11460.
    RefSeqi NP_008322.1. NC_001778.1.

    3D structure databases

    ProteinModelPortali Q95914.
    SMRi Q95914. Positions 1-261.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 808029.

    Organism-specific databases

    CTDi 4514.

    Phylogenomic databases

    HOVERGENi HBG016686.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete mitochondrial DNA sequence of the bichir (Polypterus ornatipinnis), a basal ray-finned fish: ancient establishment of the consensus vertebrate gene order."
      Noack K., Zardoya R., Meyer A.
      Genetics 144:1165-1180(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiCOX3_POLOR
    AccessioniPrimary (citable) accession number: Q95914
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3