Q95840 (COX3_MAGGR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase subunit 3
EC=1.9.3.1

Alternative name(s):
Cytochrome c oxidase polypeptide III

Gene names

Name:

COX3

Encoded on

Mitochondrion

Organism

Magnaporthe grisea (Crabgrass-specific blast fungus) (Pyricularia grisea)

Taxonomic identifier

148305 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Sordariomycetidae › Magnaporthales › Magnaporthaceae › Magnaporthe

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Subunits I, II and III form the functional core of the enzyme complex.
Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subcellular location	Mitochondrion inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	aerobic electron transport chain Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Cytochrome c oxidase subunit 3		PRO_0000183805
Regions
	Transmembrane	13 – 33	21	Helical; Potential
	Transmembrane	46 – 66	21	Helical; Potential
	Transmembrane	90 – 110	21	Helical; Potential
	Transmembrane	138 – 160	23	Helical; Potential
	Transmembrane	167 – 187	21	Helical; Potential
	Transmembrane	207 – 227	21	Helical; Potential
	Transmembrane	245 – 265	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q95840 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: AC71B68747D03FCC	FASTA	269	29,981
	10 20 30 40 50 60 MNNLVRSNFQ DHPFHLVSPS LWPLYTSISL LVLTSNAALA MHNFANGHYS VYLGLILVIS 70 80 90 100 110 120 SMSFWFRDVI TEGSFLGDHT LAVQKGLNLG VILFIVSEAL FFMAIFWAFF HSALTPTVEL 130 140 150 160 170 180 GGQWPPIGIE PINPFELPLL NTVILLSSGA TVTYAHHSII GRNREGALYG SVATVLLAIV 190 200 210 220 230 240 FTGFQGVEYS VSSFTISDGA FGTCFYFGTG FHGLHVIIGT IFLLVALWRI FAYHLTDNHH 250 260 LGFEAGILYW HFVDVVWLFL YISIYYWGS

References

[1]	Kimura M. Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	D88389 Genomic DNA. Translation: BAA13605.1.
3D structure databases
ProteinModelPortal	Q95840.
SMR	Q95840. Positions 10-269.
ModBase	Search...
Protein-protein interaction databases
STRING	148305.Q95840.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG1845.
OrthoDB	EOG4578GM.
Family and domain databases
Gene3D	1.20.120.80. 1 hit.
InterPro	IPR024791. Cyt_c/ubiquinol_Oxase_su3. IPR000298. Cyt_c_oxidase_su3. IPR013833. Cyt_c_oxidase_su3_a-hlx. [Graphical view]
PANTHER	PTHR11403. PTHR11403. 1 hit.
Pfam	PF00510. COX3. 1 hit. [Graphical view]
SUPFAM	SSF81452. CytC_oxdse_III. 1 hit.
PROSITE	PS50253. COX3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COX3_MAGGR

Accession

Primary (citable) accession number: Q95840

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	April 3, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program