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Protein

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3

Gene

NAD9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Enzyme and pathway databases

BioCyciARA:ATMG00070-MONOMER.
MetaCyc:ATMG00070-MONOMER.
ReactomeiR-ATH-6799198. Complex I biogenesis.

Protein family/group databases

TCDBi3.D.1.6.3. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
NADH dehydrogenase subunit 9
Gene namesi
Name:NAD9
Ordered Locus Names:AtMg00070
Encoded oniMitochondrion
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Mitochondrion

Organism-specific databases

TAIRiATMG00070.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 190190NADH dehydrogenase [ubiquinone] iron-sulfur protein 3PRO_0000118637Add
BLAST

Proteomic databases

PaxDbiQ95748.
PRIDEiQ95748.

Expressioni

Gene expression databases

ExpressionAtlasiQ95748. baseline and differential.
GenevisibleiQ95748. AT.

Interactioni

Subunit structurei

Complex I is composed of at least 49 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.

Protein-protein interaction databases

IntActiQ95748. 4 interactions.
STRINGi3702.ATMG00070.1.

Structurei

3D structure databases

ProteinModelPortaliQ95748.
SMRiQ95748. Positions 56-149.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Phylogenomic databases

eggNOGiKOG1713. Eukaryota.
COG0852. LUCA.
HOGENOMiHOG000009797.
InParanoidiQ95748.
KOiK03936.
OrthoDBiEOG09360N2P.

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC. 1 hit.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q95748-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNQFIFKYS WETLPKKWVK KMERSEHGNR FDTNTDYLFQ LLCFLKLHTY
60 70 80 90 100
TRVQVLIDIC GVDYPSRKRR FEVVYNLLST RYNSRIRVQT SADEVTRISS
110 120 130 140 150
VVSLFPSAGW WEREVWDMFG VSFINHPDLR RILTDYGFEG HPLRKDFPLS
160 170 180 190
GYVQVRYDDP EKRVVSEPIE MTQEFRYFDF ASPWEQRSDG
Length:190
Mass (Da):22,880
Last modified:January 16, 2004 - v2
Checksum:iFCF70F540E71BC70
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti130 – 1301R → P in BAA11532 (PubMed:8776901).Curated
Sequence conflicti154 – 1541Q → E in ABS50639 (PubMed:17565941).Curated
Sequence conflicti154 – 1541Q → E in ABS50638 (PubMed:17565941).Curated

RNA editingi

Edited at positions 31, 56, 64, 100, 110, 133 and 147.2 Publications

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D82062 Genomic DNA. Translation: BAA11532.1. Sequence problems.
Y08501 Genomic DNA. Translation: CAA69753.3. Sequence problems.
EF488926 mRNA. Translation: ABS50638.1.
EF488927 mRNA. Translation: ABS50639.1.
RefSeqiNP_085479.1. NC_001284.2.

Genome annotation databases

EnsemblPlantsiATMG00070.1; ATMG00070.1; ATMG00070.
GeneIDi814568.
GrameneiATMG00070.1; ATMG00070.1; ATMG00070.
KEGGiath:ArthMp007.

Keywords - Coding sequence diversityi

RNA editing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D82062 Genomic DNA. Translation: BAA11532.1. Sequence problems.
Y08501 Genomic DNA. Translation: CAA69753.3. Sequence problems.
EF488926 mRNA. Translation: ABS50638.1.
EF488927 mRNA. Translation: ABS50639.1.
RefSeqiNP_085479.1. NC_001284.2.

3D structure databases

ProteinModelPortaliQ95748.
SMRiQ95748. Positions 56-149.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ95748. 4 interactions.
STRINGi3702.ATMG00070.1.

Protein family/group databases

TCDBi3.D.1.6.3. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Proteomic databases

PaxDbiQ95748.
PRIDEiQ95748.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiATMG00070.1; ATMG00070.1; ATMG00070.
GeneIDi814568.
GrameneiATMG00070.1; ATMG00070.1; ATMG00070.
KEGGiath:ArthMp007.

Organism-specific databases

TAIRiATMG00070.

Phylogenomic databases

eggNOGiKOG1713. Eukaryota.
COG0852. LUCA.
HOGENOMiHOG000009797.
InParanoidiQ95748.
KOiK03936.
OrthoDBiEOG09360N2P.

Enzyme and pathway databases

BioCyciARA:ATMG00070-MONOMER.
MetaCyc:ATMG00070-MONOMER.
ReactomeiR-ATH-6799198. Complex I biogenesis.

Miscellaneous databases

PROiQ95748.

Gene expression databases

ExpressionAtlasiQ95748. baseline and differential.
GenevisibleiQ95748. AT.

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC. 1 hit.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNDUS3_ARATH
AccessioniPrimary (citable) accession number: Q95748
Secondary accession number(s): A7KNI3, P93279
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 16, 2004
Last modified: September 7, 2016
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.