Q952G2 (Q952G2_9TRYP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Guide RNA binding protein gBP25 EMBL AAK54612.1
Encoded on	Mitochondrion EMBL AAK54612.1
Organism	Trypanosoma brucei EMBL AAK54612.1
Taxonomic identifier	5691 [NCBI]
Taxonomic lineage	Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Cellular component	Mitochondrion EMBL AAK54612.1
Technical term	3D-structure PDB 2GJE PDB 2GID PDB 2GIA
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q952G2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: A0836ABF429825BC	FASTA	224	25,106
	10 20 30 40 50 60 MLRRIISQQT TLIRKPLGAA LFATSALRLE AASSSDADGK EVGSSGEGNR ATGGKWRRPS 70 80 90 100 110 120 LAQQRARRAQ LPPAFDVVHW NDEDISRGHL LRVLHRDTFV VLDYHRQARM LTEEGNKAER 130 140 150 160 170 180 VVSVMLPAVY TARFLAVLEG RSEKVEVHSR YTNATFTPNP AAPYTFTLKC TSTRPAQQKQ 190 200 210 220 QVAGEEGDET FEWTVEFDVA ESLMLQRFLT QALHYNTGFA RTSV

References

[1]	"Cloning and characterization of two guide RNA-binding proteins from mitochondria of Crithidia fasciculata: gBP27, a novel protein, and gBP29, the orthologue of Trypanosoma brucei gBP21." Blom D., van den Burg J., Breek C.K.D., Speijer D., Muijsers A.O., Benne R. Nucleic Acids Res. 29:2950-2962(2001) [PubMed: 11452020] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism." Schumacher M.A., Karamooz E., Zikova A., Trantirek L., Lukes J. Cell 126:701-711(2006) [PubMed: 16923390] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.89 ANGSTROMS) OF 30-224.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF373808 mRNA. Translation: AAK54612.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2GIA	X-ray	1.89	A/G	30-224	[»]
2GID	X-ray	3.35	A/G/H/P	30-224	[»]
2GJE	X-ray	3.37	A	30-224	[»]

ProteinModelPortal

Q952G2.

SMR

Q952G2. Positions 55-221.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q952G2. 1 interaction.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblProtists

EAN80273; EAN80273; Tb11.01.4860.

KEGG

tbr:Tb11.01.4860.

Organism-specific databases

EuPathDB

EupathDB:Tb11.01.4860.

Phylogenomic databases

eggNOG

euNOG17032.

ProtClustDB

CLSZ2443258.

Family and domain databases

InterPro

IPR018539. RNA-bd_mt.
IPR009044. ssDNA-bd_transcriptional_reg.
[Graphical view]

Pfam

PF09387. MRP. 1 hit.
[Graphical view]

SUPFAM

SSF54447. ssDNA_bind_regul. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q952G2_9TRYP

Accession

Primary (citable) accession number: Q952G2

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	November 16, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)