Q94KK7 (SYP52_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Syntaxin-52
Short name=AtSYP52

Gene names

Name:	SYP52
Ordered Locus Names:	At1g79590
ORF Names:	F20B17.2

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Vesicle trafficking protein that functions in the secretory pathway By similarity.
Subunit structure	Interacts either with VTI11 and SYP21, or with VTI11 and SYP22 in the prevacuolar compartment, or with VTI12 and SYP61 in the trans-Golgi network to form t-SNARE complexes. Ref.1
Subcellular location	Golgi apparatus › trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Tissue specificity	Expressed in root, leaf, stem, flower and silique.
Miscellaneous	SYP51 and SYP52 may have redundant functions.
Sequence similarities	Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain.
Sequence caution	The sequence AAF68106.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Golgi apparatus Membrane
Domain	Coiled coil Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	intracellular protein transport Inferred from electronic annotation. Source: InterPro vesicle-mediated transport Traceable author statement PubMed 11115874. Source: TAIR
Cellular_component	Golgi apparatus Inferred from electronic annotation. Source: UniProtKB-SubCell endosome membrane Non-traceable author statement PubMed 11115874. Source: TAIR integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW late endosome membrane Inferred from electronic annotation. Source: UniProtKB-SubCell vacuole Inferred from direct assay PubMed 15539469. Source: TAIR
Molecular_function	SNAP receptor activity Traceable author statement PubMed 11115874. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	Syntaxin-52		PRO_0000210262
Regions
	Topological domain	1 – 209	209	Cytoplasmic Potential
	Transmembrane	210 – 230	21	Helical; Anchor for type IV membrane protein; Potential
	Topological domain	231 – 233	3	Vesicular Potential
	Domain	137 – 199	63	t-SNARE coiled-coil homology

Sequences

	Sequence		Length	Mass (Da)
	Q94KK7 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: F58629FD64713BBE	FASTA	233	26,108
	10 20 30 40 50 60 MASSSDPWMR EYNEALKLSE DINGMMSERN ASGLTGPDAQ RRASAIRRKI TILGTRLDSL 70 80 90 100 110 120 QSLLVKVPGK QHVSEKEMNR RKDMVGNLRS KTNQVASALN MSNFANRDSL FGTDLKPDDA 130 140 150 160 170 180 INRVSGMDNQ GIVVFQRQVM REQDEGLEKL EETVMSTKHI ALAVNEELTL QTRLIDDLDY 190 200 210 220 230 DVDITDSRLR RVQKSLALMN KSMKSGCSCM SMLLSVLGIV GLALVIWLLV KYL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Interactions between syntaxins identify at least five SNARE complexes within the Golgi/prevacuolar system of the Arabidopsis cell." Sanderfoot A.A., Kovaleva V., Bassham D.C., Raikhel N.V. Mol. Biol. Cell 12:3733-3743(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], INTERACTION WITH SYP21; SYP22; SYP61; VTI11 AND VTI12.
[2]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF355756 mRNA. Translation: AAK40224.1. AC010793 Genomic DNA. Translation: AAF68106.1. Sequence problems. CP002684 Genomic DNA. Translation: AEE36269.1. CP002684 Genomic DNA. Translation: AEE36270.1. BT003941 mRNA. Translation: AAO41986.1. BT006106 mRNA. Translation: AAP04091.1. AY086285 mRNA. Translation: AAM64357.1.
IPI	IPI00532229.
PIR	C96827.
RefSeq	NP_001031301.1. NM_001036224.1. NP_565213.1. NM_106607.4.
UniGene	At.19840.
3D structure databases
ProteinModelPortal	Q94KK7.
SMR	Q94KK7. Positions 144-196.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G79590.1-P.
Proteomic databases
PaxDb	Q94KK7.
PRIDE	Q94KK7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G79590.1; AT1G79590.1; AT1G79590. AT1G79590.2; AT1G79590.2; AT1G79590.
GeneID	844297.
KEGG	ath:AT1G79590.
Organism-specific databases
GeneFarm	3889. 383.
TAIR	At1g79590.
Phylogenomic databases
eggNOG	NOG259218.
HOGENOM	HOG000238738.
InParanoid	Q94KK7.
KO	K08503.
OMA	DPWMKEY.
PhylomeDB	Q94KK7.
ProtClustDB	CLSN2687826.
Gene expression databases
Genevestigator	Q94KK7.
GermOnline	AT1G79590. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR006012. Syntaxin/epimorphin_CS. IPR000727. T_SNARE_dom. [Graphical view]
Pfam	PF05739. SNARE. 1 hit. [Graphical view]
PROSITE	PS00914. SYNTAXIN. 1 hit. PS50192. T_SNARE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYP52_ARATH

Accession

Primary (citable) accession number: Q94KK7
Secondary accession number(s): Q9MA16

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program