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Q94IC4 (FRI2_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin-2, chloroplastic

EC=1.16.3.1
Alternative name(s):
SFerH-2
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.

Subcellular location

Plastidchloroplast.

Sequence similarities

Belongs to the ferritin family.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

flower development

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

iron ion transport

Inferred from electronic annotation. Source: InterPro

leaf development

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

photosynthesis

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to bacterium

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to cold

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to hydrogen peroxide

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to iron ion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to zinc ion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentchloroplast stroma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast thylakoid membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

mitochondrion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 5151Chloroplast Potential
Chain52 – 257206Ferritin-2, chloroplastic
PRO_0000008865

Regions

Domain85 – 238154Ferritin-like diiron
Region52 – 8433Extension peptide (EP)

Sites

Metal binding1021Iron 1 By similarity
Metal binding1371Iron 1 By similarity
Metal binding1371Iron 2 By similarity
Metal binding1401Iron 1 By similarity
Metal binding1861Iron 2 By similarity
Metal binding2201Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q94IC4 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 9BACC4531D853EB9

FASTA25728,734
        10         20         30         40         50         60 
MALSCSKVLS FYLSPVVGGG DVPKKLTFSS FLGLSKGVGG SRSSRVCAAS NAPAPLAGVI 

        70         80         90        100        110        120 
FEPFQELKKD YLAVPIAHNV XLARQNYADD SESAINEQIN VEYNVSYVYH ALFAYFDRDN 

       130        140        150        160        170        180 
IALKGLAKFF KESSEEEREH AEQLIKYQNI RGGRVVLHPI TSPPSEFEHS EKGDALYAME 

       190        200        210        220        230        240 
LALSLEKLTN EKLLHVHSVA ERNNDPQXAD FIESEFLYEQ VKSIKKIAEY VAQLRLVGKG 

       250 
HGVWHFDQKL LHDEDHV 

« Hide

References

[1]"A novel plant ferritin subunit from soybean that is related to a mechanism in iron release."
Masuda T., Goto F., Yoshihara T.
J. Biol. Chem. 276:19575-19579(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB062754 mRNA. Translation: BAB60683.1.
RefSeqNP_001237034.1. NM_001250105.1.
UniGeneGma.56946.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ94IC4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID547988.
KEGGgmx:547988.

Gene expression databases

GenevestigatorQ94IC4.

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRI2_SOYBN
AccessionPrimary (citable) accession number: Q94IC4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families