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Q94FY2 (FRI_MALBX) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin, chloroplastic

EC=1.16.3.1
Alternative name(s):
Apf1
OrganismMalus baccata var. xiaojinensis (Apple) (Malus xiaojinensis)
Taxonomic identifier141206 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeMaloideaeMaleaeMalus

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.

Subcellular location

Plastidchloroplast By similarity.

Sequence similarities

Belongs to the ferritin family.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

iron ion transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 4949Chloroplast Potential
Chain50 – 250201Ferritin, chloroplastic
PRO_0000008861

Regions

Domain83 – 236154Ferritin-like diiron
Region50 – 8233Extension peptide (EP)

Sites

Metal binding1001Iron 1 By similarity
Metal binding1351Iron 1 By similarity
Metal binding1351Iron 2 By similarity
Metal binding1381Iron 1 By similarity
Metal binding1841Iron 2 By similarity
Metal binding2181Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q94FY2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 20EF3C1CF2A0DCDE

FASTA25028,053
        10         20         30         40         50         60 
MALAPSKVST FSGFSPKPSV GGAQKNPTCS VSLSFLNEKL GSRNLRVCAS TVPLTGVIFE 

        70         80         90        100        110        120 
PFEEVKKSEL AVPTAPQVSL ARQNYADECE SAINEQINVE YNASYVYHSL FAYFDRDNVA 

       130        140        150        160        170        180 
LKGFAKFFKE SSEEEREHAE KLMKYQNTRG GRVVLHAIKN VPSEFEHVEK GDALYAMELA 

       190        200        210        220        230        240 
LSLEKLVNEK LLNVHSVADR NNDPQMADFI ESEFLSEQVE SIKKISEYVA QLRRVGKGHG 

       250 
VWHFDQRLLD 

« Hide

References

[1]"The ferritin gene of apple trees (Malus xiaojinensis, Cheng et Jiang)."
Zhou Z.Q., Cheng M.H., Zhou Z.Y., Pei P., Yang W.G.
Chin. J. Biotechnol. 17:342-344(2001)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF315505 Genomic DNA. Translation: AAK83702.1.

3D structure databases

ProteinModelPortalQ94FY2.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ94FY2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRI_MALBX
AccessionPrimary (citable) accession number: Q94FY2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families