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Protein

Probable protein phosphatase 2C 48

Gene

PP2C6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi89Manganese 1By similarity1
Metal bindingi89Manganese 2By similarity1
Metal bindingi90Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi290Manganese 2By similarity1
Metal bindingi349Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 48 (EC:3.1.3.16)
Short name:
AtPP2C48
Alternative name(s):
Protein phosphatase 2C 6
Gene namesi
Name:PP2C6
Ordered Locus Names:At3g55050
ORF Names:T15C9.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G55050.
TAIRilocus:2097238. AT3G55050.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679721 – 384Probable protein phosphatase 2C 48Add BLAST384

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei78PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ94CL8.
PRIDEiQ94CL8.

Expressioni

Gene expression databases

ExpressionAtlasiQ94CL8. baseline and differential.
GenevisibleiQ94CL8. AT.

Interactioni

Protein-protein interaction databases

BioGridi9987. 1 interactor.
STRINGi3702.AT3G55050.1.

Structurei

3D structure databases

ProteinModelPortaliQ94CL8.
SMRiQ94CL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 358PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST312

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000238703.
InParanoidiQ94CL8.
OMAiKFRVPER.
OrthoDBiEOG09360D2T.
PhylomeDBiQ94CL8.

Family and domain databases

CDDicd00143. PP2Cc. 1 hit.
Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR000222. PP2C_BS.
IPR036457. PPM-type_dom_sf.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 1 hit.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiView protein in PROSITE
PS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q94CL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSTTFRRIV SPCWRPFGIG EDSSPGSDDT NGRLDGLLWY KDSGNHITGE
60 70 80 90 100
FSMAVVQANN LLEDHSQLES GPISLHESGP EATFVGVYDG HGGPEAARFV
110 120 130 140 150
NDRLFYNIKR YTSEQRGMSP DVITRGFVAT EEEFLGLVQE QWKTKPQIAS
160 170 180 190 200
VGACCLVGIV CNGLLYVANA GDSRVVLGKV ANPFKELKAV QLSTEHNASI
210 220 230 240 250
ESVREELRLL HPDDPNIVVL KHKVWRVKGI IQVSRSIGDA YLKRAEFNQE
260 270 280 290 300
PLLPKFRVPE RFEKPIMRAE PTITVHKIHP EDQFLIFASD GLWEHLSNQE
310 320 330 340 350
AVDIVNSCPR NGVARKLVKA ALQEAAKKRE MRYSDLEKIE RGIRRHFHDD
360 370 380
ITVIVVFLHA TNFATRTPIS VKGGGLLSAH NPVL
Length:384
Mass (Da):42,851
Last modified:December 1, 2001 - v1
Checksum:i26015C8E6737AE3A
GO

Sequence cautioni

The sequence CAB82700 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ302053 Genomic DNA. Translation: CAC44619.1.
AL132970 Genomic DNA. Translation: CAB82700.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE79332.1.
CP002686 Genomic DNA. Translation: AEE79333.1.
BT014892 mRNA. Translation: AAT44968.1.
BT021925 mRNA. Translation: AAX49374.1.
AK229292 mRNA. Translation: BAF01155.1.
PIRiT47644.
RefSeqiNP_191065.2. NM_115363.3.
NP_974438.1. NM_202709.2.
UniGeneiAt.28200.

Genome annotation databases

EnsemblPlantsiAT3G55050.1; AT3G55050.1; AT3G55050.
AT3G55050.2; AT3G55050.2; AT3G55050.
GeneIDi824671.
GrameneiAT3G55050.1; AT3G55050.1; AT3G55050.
AT3G55050.2; AT3G55050.2; AT3G55050.
KEGGiath:AT3G55050.

Similar proteinsi

Entry informationi

Entry nameiP2C48_ARATH
AccessioniPrimary (citable) accession number: Q94CL8
Secondary accession number(s): Q9M2W1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: October 25, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families