Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q94CL8

- P2C48_ARATH

UniProt

Q94CL8 - P2C48_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable protein phosphatase 2C 48

Gene

PP2C6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi89 – 891Manganese 1By similarity
Metal bindingi89 – 891Manganese 2By similarity
Metal bindingi90 – 901Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi290 – 2901Manganese 2By similarity
Metal bindingi349 – 3491Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G55050-MONOMER.
ARA:GQT-2379-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 48 (EC:3.1.3.16)
Short name:
AtPP2C48
Alternative name(s):
Protein phosphatase 2C 6
Gene namesi
Name:PP2C6
Ordered Locus Names:At3g55050
ORF Names:T15C9.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G55050.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 384384Probable protein phosphatase 2C 48PRO_0000367972Add
BLAST

Proteomic databases

PRIDEiQ94CL8.

Expressioni

Gene expression databases

GenevestigatoriQ94CL8.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G55050.2-P.

Structurei

3D structure databases

ProteinModelPortaliQ94CL8.
SMRiQ94CL8. Positions 84-360.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini84 – 330247PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000238703.
InParanoidiQ94CL8.
OMAiFRRIVSP.
PhylomeDBiQ94CL8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q94CL8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSTTFRRIV SPCWRPFGIG EDSSPGSDDT NGRLDGLLWY KDSGNHITGE
60 70 80 90 100
FSMAVVQANN LLEDHSQLES GPISLHESGP EATFVGVYDG HGGPEAARFV
110 120 130 140 150
NDRLFYNIKR YTSEQRGMSP DVITRGFVAT EEEFLGLVQE QWKTKPQIAS
160 170 180 190 200
VGACCLVGIV CNGLLYVANA GDSRVVLGKV ANPFKELKAV QLSTEHNASI
210 220 230 240 250
ESVREELRLL HPDDPNIVVL KHKVWRVKGI IQVSRSIGDA YLKRAEFNQE
260 270 280 290 300
PLLPKFRVPE RFEKPIMRAE PTITVHKIHP EDQFLIFASD GLWEHLSNQE
310 320 330 340 350
AVDIVNSCPR NGVARKLVKA ALQEAAKKRE MRYSDLEKIE RGIRRHFHDD
360 370 380
ITVIVVFLHA TNFATRTPIS VKGGGLLSAH NPVL
Length:384
Mass (Da):42,851
Last modified:December 1, 2001 - v1
Checksum:i26015C8E6737AE3A
GO

Sequence cautioni

The sequence CAB82700.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ302053 Genomic DNA. Translation: CAC44619.1.
AL132970 Genomic DNA. Translation: CAB82700.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE79332.1.
CP002686 Genomic DNA. Translation: AEE79333.1.
BT014892 mRNA. Translation: AAT44968.1.
BT021925 mRNA. Translation: AAX49374.1.
AK229292 mRNA. Translation: BAF01155.1.
PIRiT47644.
RefSeqiNP_191065.2. NM_115363.3.
NP_974438.1. NM_202709.1.
UniGeneiAt.28200.

Genome annotation databases

EnsemblPlantsiAT3G55050.1; AT3G55050.1; AT3G55050.
AT3G55050.2; AT3G55050.2; AT3G55050.
GeneIDi824671.
KEGGiath:AT3G55050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ302053 Genomic DNA. Translation: CAC44619.1 .
AL132970 Genomic DNA. Translation: CAB82700.1 . Sequence problems.
CP002686 Genomic DNA. Translation: AEE79332.1 .
CP002686 Genomic DNA. Translation: AEE79333.1 .
BT014892 mRNA. Translation: AAT44968.1 .
BT021925 mRNA. Translation: AAX49374.1 .
AK229292 mRNA. Translation: BAF01155.1 .
PIRi T47644.
RefSeqi NP_191065.2. NM_115363.3.
NP_974438.1. NM_202709.1.
UniGenei At.28200.

3D structure databases

ProteinModelPortali Q94CL8.
SMRi Q94CL8. Positions 84-360.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT3G55050.2-P.

Proteomic databases

PRIDEi Q94CL8.

Protocols and materials databases

DNASUi 824671.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G55050.1 ; AT3G55050.1 ; AT3G55050 .
AT3G55050.2 ; AT3G55050.2 ; AT3G55050 .
GeneIDi 824671.
KEGGi ath:AT3G55050.

Organism-specific databases

TAIRi AT3G55050.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000238703.
InParanoidi Q94CL8.
OMAi FRRIVSP.
PhylomeDBi Q94CL8.

Enzyme and pathway databases

BioCyci ARA:AT3G55050-MONOMER.
ARA:GQT-2379-MONOMER.

Gene expression databases

Genevestigatori Q94CL8.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "PP2C6, a new member of the PP2C family in Arabidopsis thaliana."
    Bargues M., Terol J., Paricio N., Perez-Alonso M.
    Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
    Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
    , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C48_ARATH
AccessioniPrimary (citable) accession number: Q94CL8
Secondary accession number(s): Q9M2W1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3