Q94CL8 (P2C48_ARATH) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 79.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable protein phosphatase 2C 48 Short name=AtPP2C48 EC=3.1.3.16 Alternative name(s): Protein phosphatase 2C 6 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Reference proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis![]() |
Protein attributes
| Sequence length | 384 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Catalytic activity | A phosphoprotein + H2O = a protein + phosphate. |
| Cofactor | Binds 2 magnesium or manganese ions per subunit By similarity. |
| Sequence similarities | Belongs to the PP2C family. Contains 1 PP2C-like domain. |
| Sequence caution | The sequence CAB82700.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Magnesium Manganese Metal-binding |
| Molecular function | Hydrolase Protein phosphatase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | protein dephosphorylation Inferred from electronic annotation. Source: InterPro |
| Molecular_function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 384 | 384 | Probable protein phosphatase 2C 48 | PRO_0000367972 | |||||
Regions | |||||||||
| Domain | 84 – 330 | 247 | PP2C-like | ||||||
Sites | |||||||||
| Metal binding | 89 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 89 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 90 | 1 | Manganese 1; via carbonyl oxygen By similarity | ||||||
| Metal binding | 290 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 349 | 1 | Manganese 2 By similarity | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "PP2C6, a new member of the PP2C family in Arabidopsis thaliana." Bargues M., Terol J., Paricio N., Perez-Alonso M. Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. Tabata S.Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [3] | The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia. |
| [4] | "Arabidopsis ORF clones." Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [5] | "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. Shinozaki K.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [6] | "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AJ302053 Genomic DNA. Translation: CAC44619.1. AL132970 Genomic DNA. Translation: CAB82700.1. Sequence problems. CP002686 Genomic DNA. Translation: AEE79332.1. CP002686 Genomic DNA. Translation: AEE79333.1. BT014892 mRNA. Translation: AAT44968.1. BT021925 mRNA. Translation: AAX49374.1. AK229292 mRNA. Translation: BAF01155.1. |
| IPI | IPI00516499. |
| PIR | T47644. |
| RefSeq | NP_191065.2. NM_115363.3. NP_974438.1. NM_202709.1. |
| UniGene | At.28200. |
3D structure databases | |
| ProteinModelPortal | Q94CL8. |
| SMR | Q94CL8. Positions 72-360. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 3702.AT3G55050.2-P. |
Proteomic databases | |
| PRIDE | Q94CL8. |
Protocols and materials databases | |
| DNASU | 824671. |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | AT3G55050.1; AT3G55050.1; AT3G55050. AT3G55050.2; AT3G55050.2; AT3G55050. |
| GeneID | 824671. |
| KEGG | ath:AT3G55050. |
Organism-specific databases | |
| TAIR | At3g55050. |
Phylogenomic databases | |
| eggNOG | COG0631. |
| HOGENOM | HOG000238703. |
| InParanoid | Q94CL8. |
| OMA | TEHNASI. |
| PhylomeDB | Q94CL8. |
| ProtClustDB | CLSN2680416. |
Gene expression databases | |
| Genevestigator | Q94CL8. |
Family and domain databases | |
| Gene3D | 3.60.40.10. 1 hit. |
| InterPro | IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view] |
| PANTHER | PTHR13832. PTHR13832. 1 hit. |
| Pfam | PF00481. PP2C. 1 hit. [Graphical view] |
| SMART | SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view] |
| SUPFAM | SSF81606. PP2C-related. 1 hit. |
| PROSITE | PS01032. PP2C. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | P2C48_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q94CL8 Secondary accession number(s): Q9M2W1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with
