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Protein

Probable protein S-acyltransferase 13

Gene

PAT13

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Palmitoyl acyltransferase.By similarity1 Publication

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei146S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciARA:GQT-2136-MONOMER.
BRENDAi2.3.1.225. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein S-acyltransferase 13 (EC:2.3.1.225)
Alternative name(s):
Probable palmitoyltransferase At4g22750
Zinc finger DHHC domain-containing protein At4g22750
Gene namesi
Name:PAT13
Ordered Locus Names:At4g22750
ORF Names:T12H17.140, T12H17.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G22750.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalSequence analysisAdd BLAST21
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasmic vesicle, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003636041 – 302Probable protein S-acyltransferase 13Add BLAST302

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ94C49.
PRIDEiQ94C49.

PTM databases

iPTMnetiQ94C49.
SwissPalmiQ94C49.

Expressioni

Gene expression databases

ExpressionAtlasiQ94C49. baseline and differential.
GenevisibleiQ94C49. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G22753.2.

Structurei

3D structure databases

ProteinModelPortaliQ94C49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini116 – 166DHHCPROSITE-ProRule annotationAdd BLAST51

Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated
Contains 1 DHHC domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0873. Eukaryota.
KOG1315. Eukaryota.
COG3000. LUCA.
COG5273. LUCA.
HOGENOMiHOG000234777.
InParanoidiQ94C49.
KOiK20028.
PhylomeDBiQ94C49.

Family and domain databases

InterProiIPR001594. Znf_DHHC_palmitoyltrfase.
[Graphical view]
PfamiPF01529. zf-DHHC. 1 hit.
[Graphical view]
PROSITEiPS50216. DHHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q94C49-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAWNVFKFCT ALRALGSIMI LIVIGIIGFT YYAVVVVNYG PALLIGGVDS
60 70 80 90 100
LLSVLVLAFF HFLLIMLLWS YFSVVVTDPG GVPTGWRPEL DIEKSEGNQA
110 120 130 140 150
LIGEASVGDS SSHGVRYCRK CNQYKPPRSH HCSVCGRCIL KMDHHCVWVV
160 170 180 190 200
NCVGANNYKS FLLFLFYTFL ETTVVAVSLL PIFLVFFSDG DGDITVSPGS
210 220 230 240 250
LAASFVAFVL NIAFALSVLG FLIMHIMLVA RNTTTIEAYE KHTVNWPYNV
260 270 280 290 300
GRKTNFEQVF GSDKMYWFVP LYTEDDKKKL PALGGLDFTS RSESETEPLQ

SL
Length:302
Mass (Da):33,548
Last modified:December 1, 2001 - v1
Checksum:i597AF8C359B3128A
GO

Sequence cautioni

The sequence CAA16560 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79230 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti59F → L in AAM65313 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021635 Genomic DNA. Translation: CAA16560.1. Sequence problems.
AL161557 Genomic DNA. Translation: CAB79230.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84651.1.
AY035179 mRNA. Translation: AAK59683.1.
AY062957 mRNA. Translation: AAL33803.1.
AY087777 mRNA. Translation: AAM65313.1.
PIRiT04570.
RefSeqiNP_567668.1. NM_118402.3. [Q94C49-1]
UniGeneiAt.19156.

Genome annotation databases

EnsemblPlantsiAT4G22750.1; AT4G22750.1; AT4G22750. [Q94C49-1]
GeneIDi828372.
GrameneiAT4G22750.1; AT4G22750.1; AT4G22750.
KEGGiath:AT4G22750.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021635 Genomic DNA. Translation: CAA16560.1. Sequence problems.
AL161557 Genomic DNA. Translation: CAB79230.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE84651.1.
AY035179 mRNA. Translation: AAK59683.1.
AY062957 mRNA. Translation: AAL33803.1.
AY087777 mRNA. Translation: AAM65313.1.
PIRiT04570.
RefSeqiNP_567668.1. NM_118402.3. [Q94C49-1]
UniGeneiAt.19156.

3D structure databases

ProteinModelPortaliQ94C49.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G22753.2.

PTM databases

iPTMnetiQ94C49.
SwissPalmiQ94C49.

Proteomic databases

PaxDbiQ94C49.
PRIDEiQ94C49.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G22750.1; AT4G22750.1; AT4G22750. [Q94C49-1]
GeneIDi828372.
GrameneiAT4G22750.1; AT4G22750.1; AT4G22750.
KEGGiath:AT4G22750.

Organism-specific databases

TAIRiAT4G22750.

Phylogenomic databases

eggNOGiKOG0873. Eukaryota.
KOG1315. Eukaryota.
COG3000. LUCA.
COG5273. LUCA.
HOGENOMiHOG000234777.
InParanoidiQ94C49.
KOiK20028.
PhylomeDBiQ94C49.

Enzyme and pathway databases

BioCyciARA:GQT-2136-MONOMER.
BRENDAi2.3.1.225. 399.

Miscellaneous databases

PROiQ94C49.

Gene expression databases

ExpressionAtlasiQ94C49. baseline and differential.
GenevisibleiQ94C49. AT.

Family and domain databases

InterProiIPR001594. Znf_DHHC_palmitoyltrfase.
[Graphical view]
PfamiPF01529. zf-DHHC. 1 hit.
[Graphical view]
PROSITEiPS50216. DHHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZDH18_ARATH
AccessioniPrimary (citable) accession number: Q94C49
Secondary accession number(s): O49656, Q8LAJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.