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Q94BT2

- AIR12_ARATH

UniProt

Q94BT2 - AIR12_ARATH

Protein

Auxin-induced in root cultures protein 12

Gene

AIR12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 3 (31 Oct 2003)
      Previous versions | rss
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    Functioni

    One-heme-containing cytochrome.1 Publication

    Cofactori

    Binds 1 heme group non-covalently.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi91 – 911Iron (heme axial ligand)Sequence Analysis
    Metal bindingi176 – 1761Iron (heme axial ligand)Sequence Analysis

    GO - Biological processi

    1. auxin-activated signaling pathway Source: UniProtKB-KW

    Keywords - Biological processi

    Auxin signaling pathway, Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Auxin-induced in root cultures protein 12
    Gene namesi
    Name:AIR12
    Ordered Locus Names:At3g07390
    ORF Names:F21O3_10
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G07390.

    Subcellular locationi

    GO - Cellular componenti

    1. anchored component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 228203Auxin-induced in root cultures protein 12PRO_0000020655Add
    BLAST
    Propeptidei229 – 25224Removed in mature formSequence AnalysisPRO_0000020656Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi58 – 581N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi61 – 611N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi114 – 1141N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi167 – 1671N-linked (GlcNAc...)Sequence Analysis
    Lipidationi228 – 2281GPI-anchor amidated glycineSequence Analysis

    Keywords - PTMi

    Glycoprotein, GPI-anchor, Lipoprotein

    Proteomic databases

    PaxDbiQ94BT2.
    PRIDEiQ94BT2.

    Expressioni

    Developmental stagei

    Expressed during auxin-induced lateral root formation.1 Publication

    Inductioni

    Induced between 4 and 8 hours after treatment with auxin and remains high for at least 24 hours.2 Publications

    Gene expression databases

    GenevestigatoriQ94BT2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ94BT2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini49 – 165117DOMONPROSITE-ProRule annotationAdd
    BLAST

    Domaini

    DOMON domain could bind one heme b.1 Publication

    Sequence similaritiesi

    Contains 1 DOMON domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG307188.
    HOGENOMiHOG000239821.
    InParanoidiQ94BT2.
    PhylomeDBiQ94BT2.

    Family and domain databases

    InterProiIPR005018. DOMON_domain.
    IPR017214. UCP037471.
    [Graphical view]
    PfamiPF04526. DUF568. 1 hit.
    [Graphical view]
    SMARTiSM00664. DoH. 1 hit.
    [Graphical view]
    PROSITEiPS50836. DOMON. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q94BT2-1 [UniParc]FASTAAdd to Basket

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    MASSSSSLLI LAVACFVSLI SPAISQQACK SQNLNSAGPF DSCEDLPVLN    50
    SYLHYTYNSS NSSLSVAFVA TPSQANGGWV AWAINPTGTK MAGSQAFLAY 100
    RSGGGAAPVV KTYNISSYSS LVEGKLAFDF WNLRAESLSG GRIAIFTTVK 150
    VPAGADSVNQ VWQIGGNVTN GRPGVHPFGP DNLGSHRVLS FTEDAAPGSA 200
    PSPGSAPAPG TSGSTTPGTA AGGPGNAGSL TRNVNFGVNL GILVLLGSIF 250
    IF 252
    Length:252
    Mass (Da):25,592
    Last modified:October 31, 2003 - v3
    Checksum:iDB20541FE856E603
    GO

    Sequence cautioni

    The sequence AAC62613.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAK64012.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence AEE74537.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti147 – 1471T → NR in AAC62613. (PubMed:10080694)Curated
    Sequence conflicti155 – 1551A → R in AAC62613. (PubMed:10080694)Curated
    Sequence conflicti207 – 2071P → PSPGSAP in AAC62613. (PubMed:10080694)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF055850 mRNA. Translation: AAC62613.1. Different initiation.
    AC009853 Genomic DNA. Translation: AAF02148.1.
    CP002686 Genomic DNA. Translation: AEE74537.1. Different initiation.
    AY039908 mRNA. Translation: AAK64012.2. Different initiation.
    AY077679 mRNA. Translation: AAL76157.1.
    PIRiT51337.
    RefSeqiNP_566306.3. NM_111618.3.
    UniGeneiAt.48629.

    Genome annotation databases

    EnsemblPlantsiAT3G07390.1; AT3G07390.1; AT3G07390.
    GeneIDi819927.
    KEGGiath:AT3G07390.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF055850 mRNA. Translation: AAC62613.1 . Different initiation.
    AC009853 Genomic DNA. Translation: AAF02148.1 .
    CP002686 Genomic DNA. Translation: AEE74537.1 . Different initiation.
    AY039908 mRNA. Translation: AAK64012.2 . Different initiation.
    AY077679 mRNA. Translation: AAL76157.1 .
    PIRi T51337.
    RefSeqi NP_566306.3. NM_111618.3.
    UniGenei At.48629.

    3D structure databases

    ProteinModelPortali Q94BT2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q94BT2.
    PRIDEi Q94BT2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G07390.1 ; AT3G07390.1 ; AT3G07390 .
    GeneIDi 819927.
    KEGGi ath:AT3G07390.

    Organism-specific databases

    TAIRi AT3G07390.

    Phylogenomic databases

    eggNOGi NOG307188.
    HOGENOMi HOG000239821.
    InParanoidi Q94BT2.
    PhylomeDBi Q94BT2.

    Gene expression databases

    Genevestigatori Q94BT2.

    Family and domain databases

    InterProi IPR005018. DOMON_domain.
    IPR017214. UCP037471.
    [Graphical view ]
    Pfami PF04526. DUF568. 1 hit.
    [Graphical view ]
    SMARTi SM00664. DoH. 1 hit.
    [Graphical view ]
    PROSITEi PS50836. DOMON. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of cDNA clones corresponding with mRNAs that accumulate during auxin-induced lateral root formation."
      Neuteboom L.W., Ng J.M.Y., Kuyper M., Clijdesdale O.R., Hooykaas P.J.J., van der Zaal B.J.
      Plant Mol. Biol. 39:273-287(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, DEVELOPMENTAL STAGE.
      Strain: cv. C24.
      Tissue: Cultured root.
    2. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-252.
      Strain: cv. Columbia.
    5. "Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry."
      Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
      Mol. Cell. Proteomics 2:1234-1243(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: cv. La-0.
    6. "Identification of glycosylphosphatidylinositol-anchored proteins in Arabidopsis. A proteomic and genomic analysis."
      Borner G.H.H., Lilley K.S., Stevens T.J., Dupree P.
      Plant Physiol. 132:568-577(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS].
      Strain: cv. Columbia.
      Tissue: Callus.
    7. "Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins."
      Elortza F., Nuehse T.S., Foster L.J., Stensballe A., Peck S.C., Jensen O.N.
      Mol. Cell. Proteomics 2:1261-1270(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS].
    8. "Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
      Elortza F., Mohammed S., Bunkenborg J., Foster L.J., Nuehse T.S., Brodbeck U., Peck S.C., Jensen O.N.
      J. Proteome Res. 5:935-943(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS].
    9. "Expression profiling of auxin-treated Arabidopsis roots: toward a molecular analysis of lateral root emergence."
      Laskowski M., Biller S., Stanley K., Kajstura T., Prusty R.
      Plant Cell Physiol. 47:788-792(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION BY AUXIN.
    10. "Auxin-responsive genes AIR12 code for a new family of plasma membrane b-type cytochromes specific to flowering plants."
      Preger V., Tango N., Marchand C., Lemaire S.D., Carbonera D., Di Valentin M., Costa A., Pupillo P., Trost P.
      Plant Physiol. 150:606-620(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: COFACTOR, FUNCTION, DOMAIN.

    Entry informationi

    Entry nameiAIR12_ARATH
    AccessioniPrimary (citable) accession number: Q94BT2
    Secondary accession number(s): F4JEF2, O82442, Q9SRS7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2003
    Last sequence update: October 31, 2003
    Last modified: October 1, 2014
    This is version 85 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3