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Protein

Sugar transport protein 13

Gene

STP13

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.By similarity

GO - Molecular functioni

  • hexose:proton symporter activity Source: TAIR
  • high-affinity hydrogen:glucose symporter activity Source: TAIR
  • monosaccharide transmembrane transporter activity Source: TAIR

GO - Biological processi

  • glucose import Source: GO_Central
  • glucose transmembrane transport Source: GOC
  • hexose transmembrane transport Source: GOC
  • monosaccharide transport Source: TAIR
  • response to abscisic acid Source: TAIR
  • response to salt stress Source: TAIR
  • response to water deprivation Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Symport, Transport

Protein family/group databases

TCDBi2.A.1.1.50. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transport protein 13
Alternative name(s):
Hexose transporter 13
Multicopy suppressor of snf4 deficiency protein 1
Gene namesi
Name:STP13
Synonyms:MSS1
Ordered Locus Names:At5g26340
ORF Names:F9D12.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G26340.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1818CytoplasmicSequence analysisAdd
BLAST
Transmembranei19 – 3921HelicalSequence analysisAdd
BLAST
Topological domaini40 – 8142ExtracellularSequence analysisAdd
BLAST
Transmembranei82 – 10221HelicalSequence analysisAdd
BLAST
Topological domaini103 – 1119CytoplasmicSequence analysis
Transmembranei112 – 13221HelicalSequence analysisAdd
BLAST
Topological domaini133 – 1419ExtracellularSequence analysis
Transmembranei142 – 16221HelicalSequence analysisAdd
BLAST
Topological domaini163 – 1686CytoplasmicSequence analysis
Transmembranei169 – 18921HelicalSequence analysisAdd
BLAST
Topological domaini190 – 20314ExtracellularSequence analysisAdd
BLAST
Transmembranei204 – 22421HelicalSequence analysisAdd
BLAST
Topological domaini225 – 29672CytoplasmicSequence analysisAdd
BLAST
Transmembranei297 – 31721HelicalSequence analysisAdd
BLAST
Topological domaini318 – 3192ExtracellularSequence analysis
Transmembranei320 – 34021HelicalSequence analysisAdd
BLAST
Topological domaini341 – 3499CytoplasmicSequence analysis
Transmembranei350 – 37021HelicalSequence analysisAdd
BLAST
Topological domaini371 – 38313ExtracellularSequence analysisAdd
BLAST
Transmembranei384 – 40421HelicalSequence analysisAdd
BLAST
Topological domaini405 – 42622CytoplasmicSequence analysisAdd
BLAST
Transmembranei427 – 44721HelicalSequence analysisAdd
BLAST
Topological domaini448 – 4514ExtracellularSequence analysis
Transmembranei452 – 47221HelicalSequence analysisAdd
BLAST
Topological domaini473 – 52654CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 526526Sugar transport protein 13PRO_0000050443Add
BLAST

Proteomic databases

PaxDbiQ94AZ2.
PRIDEiQ94AZ2.

PTM databases

iPTMnetiQ94AZ2.
SwissPalmiQ94AZ2.

Expressioni

Gene expression databases

GenevisibleiQ94AZ2. AT.

Interactioni

Protein-protein interaction databases

BioGridi17978. 3 interactions.
STRINGi3702.AT5G26340.1.

Structurei

3D structure databases

ProteinModelPortaliQ94AZ2.
SMRiQ94AZ2. Positions 28-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202867.
InParanoidiQ94AZ2.
OMAiHHIVNGK.
PhylomeDBiQ94AZ2.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q94AZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGGGFATSA NGVEFEAKIT PIVIISCIMA ATGGLMFGYD VGVSGGVTSM
60 70 80 90 100
PDFLEKFFPV VYRKVVAGAD KDSNYCKYDN QGLQLFTSSL YLAGLTATFF
110 120 130 140 150
ASYTTRTLGR RLTMLIAGVF FIIGVALNAG AQDLAMLIAG RILLGCGVGF
160 170 180 190 200
ANQAVPLFLS EIAPTRIRGG LNILFQLNVT IGILFANLVN YGTAKIKGGW
210 220 230 240 250
GWRLSLGLAG IPALLLTVGA LLVTETPNSL VERGRLDEGK AVLRRIRGTD
260 270 280 290 300
NVEPEFADLL EASRLAKEVK HPFRNLLQRR NRPQLVIAVA LQIFQQCTGI
310 320 330 340 350
NAIMFYAPVL FSTLGFGSDA SLYSAVVTGA VNVLSTLVSI YSVDKVGRRV
360 370 380 390 400
LLLEAGVQMF FSQVVIAIIL GVKVTDTSTN LSKGFAILVV VMICTYVAAF
410 420 430 440 450
AWSWGPLGWL IPSETFPLET RSAGQSVTVC VNLLFTFIIA QAFLSMLCHF
460 470 480 490 500
KFGIFIFFSA WVLIMSVFVM FLLPETKNIP IEEMTERVWK KHWFWARFMD
510 520
DHNDHEFVNG EKSNGKSNGF DPSTRL
Length:526
Mass (Da):57,419
Last modified:January 24, 2006 - v2
Checksum:i8214C8D6B93F32C1
GO

Sequence cautioni

The sequence AAK73949.1 differs from that shown. Reason: Erroneous termination at position 345. Translated as Lys.Curated
The sequence AAN28848.1 differs from that shown. Reason: Erroneous termination at position 345. Translated as Lys.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti316 – 3161F → Y in AAK73949 (PubMed:14593172).Curated
Sequence conflicti316 – 3161F → Y in AAN28848 (PubMed:14593172).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF250340 mRNA. Translation: AAG10146.1.
AJ344338 mRNA. Translation: CAC69074.1.
AF077407 Genomic DNA. Translation: AAC26243.1.
CP002688 Genomic DNA. Translation: AED93553.1.
AY045591 mRNA. Translation: AAK73949.1. Sequence problems.
AY052692 mRNA. Translation: AAK96596.1.
AY143909 mRNA. Translation: AAN28848.1. Sequence problems.
AK230023 mRNA. Translation: BAF01845.1.
PIRiT01853.
RefSeqiNP_198006.1. NM_122535.3.
UniGeneiAt.24074.

Genome annotation databases

EnsemblPlantsiAT5G26340.1; AT5G26340.1; AT5G26340.
GeneIDi832703.
GrameneiAT5G26340.1; AT5G26340.1; AT5G26340.
KEGGiath:AT5G26340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF250340 mRNA. Translation: AAG10146.1.
AJ344338 mRNA. Translation: CAC69074.1.
AF077407 Genomic DNA. Translation: AAC26243.1.
CP002688 Genomic DNA. Translation: AED93553.1.
AY045591 mRNA. Translation: AAK73949.1. Sequence problems.
AY052692 mRNA. Translation: AAK96596.1.
AY143909 mRNA. Translation: AAN28848.1. Sequence problems.
AK230023 mRNA. Translation: BAF01845.1.
PIRiT01853.
RefSeqiNP_198006.1. NM_122535.3.
UniGeneiAt.24074.

3D structure databases

ProteinModelPortaliQ94AZ2.
SMRiQ94AZ2. Positions 28-490.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi17978. 3 interactions.
STRINGi3702.AT5G26340.1.

Protein family/group databases

TCDBi2.A.1.1.50. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiQ94AZ2.
SwissPalmiQ94AZ2.

Proteomic databases

PaxDbiQ94AZ2.
PRIDEiQ94AZ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G26340.1; AT5G26340.1; AT5G26340.
GeneIDi832703.
GrameneiAT5G26340.1; AT5G26340.1; AT5G26340.
KEGGiath:AT5G26340.

Organism-specific databases

TAIRiAT5G26340.

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202867.
InParanoidiQ94AZ2.
OMAiHHIVNGK.
PhylomeDBiQ94AZ2.

Miscellaneous databases

PROiQ94AZ2.

Gene expression databases

GenevisibleiQ94AZ2. AT.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Functional identification of an Arabidopsis Snf4 ortholog by screening for heterologous multicopy suppressors of snf4 deficiency in yeast."
    Kleinow T., Bhalerao R., Breuer F., Umeda M., Salchert K., Koncz C.
    Plant J. 23:115-122(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "STP13, a new monosaccharide/H+ symporter from Arabidopsis thaliana."
    Buettner M.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  4. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  5. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 360-526.
    Strain: cv. Columbia.
  7. "Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry."
    Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
    Mol. Cell. Proteomics 2:1234-1243(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: cv. La-0.
  8. "Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database."
    Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
    Plant Cell 16:2394-2405(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  9. "The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages."
    Johnson D.A., Hill J.P., Thomas M.A.
    BMC Evol. Biol. 6:64-64(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiSTP13_ARATH
AccessioniPrimary (citable) accession number: Q94AZ2
Secondary accession number(s): O81501, Q0WM12
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: January 24, 2006
Last modified: February 17, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.