Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q94AZ2 (STP13_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified October 19, 2011. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sugar transport protein 13
Alternative name(s):
Hexose transporter 13
Multicopy suppressor of snf4 deficiency protein 1
Gene names
Name:STP13
Synonyms:MSS1
Ordered Locus Names:At5g26340
ORF Names:F9D12.17
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Mediates an active uptake of hexoses, probably by sugar/hydrogen symport By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Probable Ref.8.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Sequence caution

The sequence AAK73949.1 differs from that shown. Reason: Erroneous termination at position 345. Translated as Lys.

The sequence AAN28848.1 differs from that shown. Reason: Erroneous termination at position 345. Translated as Lys.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 526526Sugar transport protein 13
PRO_0000050443

Regions

Topological domain1 – 1818Cytoplasmic Potential
Transmembrane19 – 3921Helical; Potential
Topological domain40 – 8142Extracellular Potential
Transmembrane82 – 10221Helical; Potential
Topological domain103 – 1119Cytoplasmic Potential
Transmembrane112 – 13221Helical; Potential
Topological domain133 – 1419Extracellular Potential
Transmembrane142 – 16221Helical; Potential
Topological domain163 – 1686Cytoplasmic Potential
Transmembrane169 – 18921Helical; Potential
Topological domain190 – 20314Extracellular Potential
Transmembrane204 – 22421Helical; Potential
Topological domain225 – 29672Cytoplasmic Potential
Transmembrane297 – 31721Helical; Potential
Topological domain318 – 3192Extracellular Potential
Transmembrane320 – 34021Helical; Potential
Topological domain341 – 3499Cytoplasmic Potential
Transmembrane350 – 37021Helical; Potential
Topological domain371 – 38313Extracellular Potential
Transmembrane384 – 40421Helical; Potential
Topological domain405 – 42622Cytoplasmic Potential
Transmembrane427 – 44721Helical; Potential
Topological domain448 – 4514Extracellular Potential
Transmembrane452 – 47221Helical; Potential
Topological domain473 – 52654Cytoplasmic Potential

Amino acid modifications

Modified residue5131Phosphoserine Ref.7 Ref.8

Experimental info

Sequence conflict3161F → Y in AAK73949. Ref.5
Sequence conflict3161F → Y in AAN28848. Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q94AZ2 [UniParc].

Last modified January 24, 2006. Version 2.
Checksum: 8214C8D6B93F32C1

FASTA52657,419
        10         20         30         40         50         60 
MTGGGFATSA NGVEFEAKIT PIVIISCIMA ATGGLMFGYD VGVSGGVTSM PDFLEKFFPV 

        70         80         90        100        110        120 
VYRKVVAGAD KDSNYCKYDN QGLQLFTSSL YLAGLTATFF ASYTTRTLGR RLTMLIAGVF 

       130        140        150        160        170        180 
FIIGVALNAG AQDLAMLIAG RILLGCGVGF ANQAVPLFLS EIAPTRIRGG LNILFQLNVT 

       190        200        210        220        230        240 
IGILFANLVN YGTAKIKGGW GWRLSLGLAG IPALLLTVGA LLVTETPNSL VERGRLDEGK 

       250        260        270        280        290        300 
AVLRRIRGTD NVEPEFADLL EASRLAKEVK HPFRNLLQRR NRPQLVIAVA LQIFQQCTGI 

       310        320        330        340        350        360 
NAIMFYAPVL FSTLGFGSDA SLYSAVVTGA VNVLSTLVSI YSVDKVGRRV LLLEAGVQMF 

       370        380        390        400        410        420 
FSQVVIAIIL GVKVTDTSTN LSKGFAILVV VMICTYVAAF AWSWGPLGWL IPSETFPLET 

       430        440        450        460        470        480 
RSAGQSVTVC VNLLFTFIIA QAFLSMLCHF KFGIFIFFSA WVLIMSVFVM FLLPETKNIP 

       490        500        510        520 
IEEMTERVWK KHWFWARFMD DHNDHEFVNG EKSNGKSNGF DPSTRL

« Hide

References

« Hide 'large scale' references
[1]"Functional identification of an Arabidopsis Snf4 ortholog by screening for heterologous multicopy suppressors of snf4 deficiency in yeast."
Kleinow T., Bhalerao R., Breuer F., Umeda M., Salchert K., Koncz C.
Plant J. 23:115-122(2000) [PubMed: 10929106] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"STP13, a new monosaccharide/H+ symporter from Arabidopsis thaliana."
Buettner M.
Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed: 11130714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[5]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 360-526.
Strain: cv. Columbia.
[7]"Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry."
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
Mol. Cell. Proteomics 2:1234-1243(2003) [PubMed: 14506206] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-513, MASS SPECTROMETRY.
Strain: cv. La-0.
[8]"Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database."
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
Plant Cell 16:2394-2405(2004) [PubMed: 15308754] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-513, SUBCELLULAR LOCATION, MASS SPECTROMETRY.
[9]"The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages."
Johnson D.A., Hill J.P., Thomas M.A.
BMC Evol. Biol. 6:64-64(2006) [PubMed: 16923188] [Abstract]
Cited for: GENE FAMILY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF250340 mRNA. Translation: AAG10146.1.
AJ344338 mRNA. Translation: CAC69074.1.
AF077407 Genomic DNA. Translation: AAC26243.1.
CP002688 Genomic DNA. Translation: AED93553.1.
AY045591 mRNA. Translation: AAK73949.1. Sequence problems.
AY052692 mRNA. Translation: AAK96596.1.
AY143909 mRNA. Translation: AAN28848.1. Sequence problems.
AK230023 mRNA. Translation: BAF01845.1.
IPIIPI00546272.
PIRT01853.
RefSeqNP_198006.1. NM_122535.3.
UniGeneAt.24074.

3D structure databases

ProteinModelPortalQ94AZ2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ94AZ2.

Protein family/group databases

TCDB2.A.1.1.50. major facilitator superfamily (MFS).

Proteomic databases

PRIDEQ94AZ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G26340.1; AT5G26340.1; AT5G26340.
GeneID832703.
GenomeReviewsGene locus AT5G26340 in contig BA000015_GR.
KEGGath:AT5G26340.
NMPDRfig|3702.1.peg.24838.

Organism-specific databases

TAIRAt5g26340.

Phylogenomic databases

eggNOGKOG0254.
GeneTreeEPGT00070000028469.
HOGENOMHBG744444.
InParanoidQ94AZ2.
OMACTGINAI.
PhylomeDBQ94AZ2.
ProtClustDBCLSN2686934.

Gene expression databases

GenevestigatorQ94AZ2.
GermOnlineAT5G26340. Arabidopsis thaliana.

Family and domain databases

InterProIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSPR00171. SUGRTRNSPORT.
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
TIGRFAMsTIGR00879. SP. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSTP13_ARATH
AccessionPrimary (citable) accession number: Q94AZ2
Secondary accession number(s): O81501, Q0WM12
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: January 24, 2006
Last modified: October 19, 2011
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents