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Q94AV5

- WIP3_ARATH

UniProt

Q94AV5 - WIP3_ARATH

Protein

WPP domain-interacting protein 3

Gene

WIP3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips.1 Publication

    GO - Biological processi

    1. nucleus organization Source: TAIR

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    WPP domain-interacting protein 3
    Gene namesi
    Name:WIP3
    Ordered Locus Names:At3g13360
    ORF Names:MDC11.15
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G13360.

    Subcellular locationi

    Nucleus envelope 1 Publication. Nucleus membrane 1 Publication; Single-pass membrane protein 1 Publication; Cytoplasmic side 1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. nuclear envelope Source: TAIR
    3. nuclear membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 459459WPP domain-interacting protein 3PRO_0000347198Add
    BLAST

    Proteomic databases

    PaxDbiQ94AV5.
    PRIDEiQ94AV5.

    Expressioni

    Tissue specificityi

    Expressed in seedlings, roots, stems, leaves, and flowers.1 Publication

    Developmental stagei

    First observed in roots and cotyledons of young developing seedlings. Later confined to root tips and cauline leaves tips. In flowers, detected in the stamens and at the senescence region of developing siliques.1 Publication

    Gene expression databases

    GenevestigatoriQ94AV5.

    Interactioni

    Subunit structurei

    Component of Ran complexes at least composed of WIT1 or WIT2, RANGAP1 or RANGAP2, and WIP1 or WIP2 or WIP3 By similarity. Interacts with RANGAP1, WPP1/MAF1, and WPP2/MAF2.By similarity1 Publication

    Protein-protein interaction databases

    BioGridi5870. 1 interaction.
    IntActiQ94AV5. 4 interactions.
    STRINGi3702.AT3G13360.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ94AV5.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei427 – 44721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili331 – 37545Sequence AnalysisAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi60 – 612Nuclear localization signal 1By similarity
    Motifi63 – 642Nuclear localization signal 2By similarity
    Motifi86 – 872Nuclear localization signal 3By similarity

    Keywords - Domaini

    Coiled coil, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG281074.
    HOGENOMiHOG000093093.
    InParanoidiQ9LTT2.
    OMAiFEKSEEH.
    PhylomeDBiQ94AV5.

    Sequencei

    Sequence statusi: Complete.

    Q94AV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNESVPDSVE DNGNSVPANG LLVLPDNDHE EGGVGSPQRS NSVESPGGSV    50
    HSTRKGFGLK KWRRIKRDGP VRDEAAPVDD GSKLLKRGLA GLVNPPSKHV 100
    EFSSVEARQS SEGSVGSVNM VHHPGVANGF SPDIGCMFAV GQAFEKSEEH 150
    SGNTIGGKNV VGGKVVSGSQ EKLWSDTIKR ASEERGDIEK EKPCSSLDSD 200
    LRSSDFVFST GSVSVGNHGE KDERLTMNYI GGFSNEGQVK EEVQTYSRSE 250
    NGNKEDDGES KKNNNHWADK DALADSIRSF AVLQEVLWKE VQSFQELGKE 300
    SVLLHSNTDE LSSDQPSHQN CKEDNSTSSG SKALILKEKV KLLEHKLEEA 350
    RAALEAKEAR IQELENSKIE SELECIFQRK IETEIEHLML TRSLSSLQVL 400
    QETKKLHSLK EDPVSNRGNI LGKTCKLGFY ILTQLILLVS ILRFLVLQFS 450
    PASRLVIPT 459
    Length:459
    Mass (Da):50,274
    Last modified:December 1, 2001 - v1
    Checksum:i6FAD2C63953AAC07
    GO

    Sequence cautioni

    The sequence BAB02805.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB024034 Genomic DNA. Translation: BAB02805.1. Sequence problems.
    CP002686 Genomic DNA. Translation: AEE75338.1.
    AY045697 mRNA. Translation: AAK74055.1.
    AY149963 mRNA. Translation: AAN31117.1.
    RefSeqiNP_566455.1. NM_112181.4.
    UniGeneiAt.20916.

    Genome annotation databases

    EnsemblPlantsiAT3G13360.1; AT3G13360.1; AT3G13360.
    GeneIDi820536.
    KEGGiath:AT3G13360.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB024034 Genomic DNA. Translation: BAB02805.1 . Sequence problems.
    CP002686 Genomic DNA. Translation: AEE75338.1 .
    AY045697 mRNA. Translation: AAK74055.1 .
    AY149963 mRNA. Translation: AAN31117.1 .
    RefSeqi NP_566455.1. NM_112181.4.
    UniGenei At.20916.

    3D structure databases

    ProteinModelPortali Q94AV5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 5870. 1 interaction.
    IntActi Q94AV5. 4 interactions.
    STRINGi 3702.AT3G13360.1-P.

    Proteomic databases

    PaxDbi Q94AV5.
    PRIDEi Q94AV5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G13360.1 ; AT3G13360.1 ; AT3G13360 .
    GeneIDi 820536.
    KEGGi ath:AT3G13360.

    Organism-specific databases

    TAIRi AT3G13360.

    Phylogenomic databases

    eggNOGi NOG281074.
    HOGENOMi HOG000093093.
    InParanoidi Q9LTT2.
    OMAi FEKSEEH.
    PhylomeDBi Q94AV5.

    Gene expression databases

    Genevestigatori Q94AV5.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
      Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
      DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins."
      Xu X.M., Meulia T., Meier I.
      Curr. Biol. 17:1157-1163(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, INTERACTION WITH RANGAP1; WPP1 AND WPP2.
    5. "Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
      Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
      Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiWIP3_ARATH
    AccessioniPrimary (citable) accession number: Q94AV5
    Secondary accession number(s): Q9LTT2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names

    External Data

    Dasty 3