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Q94AV5

- WIP3_ARATH

UniProt

Q94AV5 - WIP3_ARATH

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Protein
WPP domain-interacting protein 3
Gene
WIP3, At3g13360, MDC11.15
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips.1 Publication

GO - Biological processi

  1. nucleus organization Source: TAIR
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
WPP domain-interacting protein 3
Gene namesi
Name:WIP3
Ordered Locus Names:At3g13360
ORF Names:MDC11.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G13360.

Subcellular locationi

Nucleus envelope. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei427 – 44721Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. nuclear envelope Source: TAIR
  3. nuclear membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459WPP domain-interacting protein 3
PRO_0000347198Add
BLAST

Proteomic databases

PaxDbiQ94AV5.
PRIDEiQ94AV5.

Expressioni

Tissue specificityi

Expressed in seedlings, roots, stems, leaves, and flowers.1 Publication

Developmental stagei

First observed in roots and cotyledons of young developing seedlings. Later confined to root tips and cauline leaves tips. In flowers, detected in the stamens and at the senescence region of developing siliques.1 Publication

Gene expression databases

GenevestigatoriQ94AV5.

Interactioni

Subunit structurei

Component of Ran complexes at least composed of WIT1 or WIT2, RANGAP1 or RANGAP2, and WIP1 or WIP2 or WIP3 By similarity. Interacts with RANGAP1, WPP1/MAF1, and WPP2/MAF2.1 Publication

Protein-protein interaction databases

BioGridi5870. 1 interaction.
IntActiQ94AV5. 4 interactions.
STRINGi3702.AT3G13360.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ94AV5.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili331 – 37545 Reviewed prediction
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi60 – 612Nuclear localization signal 1 By similarity
Motifi63 – 642Nuclear localization signal 2 By similarity
Motifi86 – 872Nuclear localization signal 3 By similarity

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG281074.
HOGENOMiHOG000093093.
InParanoidiQ9LTT2.
OMAiFEKSEEH.
PhylomeDBiQ94AV5.

Sequencei

Sequence statusi: Complete.

Q94AV5-1 [UniParc]FASTAAdd to Basket

« Hide

MNESVPDSVE DNGNSVPANG LLVLPDNDHE EGGVGSPQRS NSVESPGGSV    50
HSTRKGFGLK KWRRIKRDGP VRDEAAPVDD GSKLLKRGLA GLVNPPSKHV 100
EFSSVEARQS SEGSVGSVNM VHHPGVANGF SPDIGCMFAV GQAFEKSEEH 150
SGNTIGGKNV VGGKVVSGSQ EKLWSDTIKR ASEERGDIEK EKPCSSLDSD 200
LRSSDFVFST GSVSVGNHGE KDERLTMNYI GGFSNEGQVK EEVQTYSRSE 250
NGNKEDDGES KKNNNHWADK DALADSIRSF AVLQEVLWKE VQSFQELGKE 300
SVLLHSNTDE LSSDQPSHQN CKEDNSTSSG SKALILKEKV KLLEHKLEEA 350
RAALEAKEAR IQELENSKIE SELECIFQRK IETEIEHLML TRSLSSLQVL 400
QETKKLHSLK EDPVSNRGNI LGKTCKLGFY ILTQLILLVS ILRFLVLQFS 450
PASRLVIPT 459
Length:459
Mass (Da):50,274
Last modified:December 1, 2001 - v1
Checksum:i6FAD2C63953AAC07
GO

Sequence cautioni

The sequence BAB02805.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB024034 Genomic DNA. Translation: BAB02805.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE75338.1.
AY045697 mRNA. Translation: AAK74055.1.
AY149963 mRNA. Translation: AAN31117.1.
RefSeqiNP_566455.1. NM_112181.4.
UniGeneiAt.20916.

Genome annotation databases

EnsemblPlantsiAT3G13360.1; AT3G13360.1; AT3G13360.
GeneIDi820536.
KEGGiath:AT3G13360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB024034 Genomic DNA. Translation: BAB02805.1 . Sequence problems.
CP002686 Genomic DNA. Translation: AEE75338.1 .
AY045697 mRNA. Translation: AAK74055.1 .
AY149963 mRNA. Translation: AAN31117.1 .
RefSeqi NP_566455.1. NM_112181.4.
UniGenei At.20916.

3D structure databases

ProteinModelPortali Q94AV5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 5870. 1 interaction.
IntActi Q94AV5. 4 interactions.
STRINGi 3702.AT3G13360.1-P.

Proteomic databases

PaxDbi Q94AV5.
PRIDEi Q94AV5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G13360.1 ; AT3G13360.1 ; AT3G13360 .
GeneIDi 820536.
KEGGi ath:AT3G13360.

Organism-specific databases

TAIRi AT3G13360.

Phylogenomic databases

eggNOGi NOG281074.
HOGENOMi HOG000093093.
InParanoidi Q9LTT2.
OMAi FEKSEEH.
PhylomeDBi Q94AV5.

Gene expression databases

Genevestigatori Q94AV5.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Anchorage of plant RanGAP to the nuclear envelope involves novel nuclear-pore-associated proteins."
    Xu X.M., Meulia T., Meier I.
    Curr. Biol. 17:1157-1163(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, INTERACTION WITH RANGAP1; WPP1 AND WPP2.
  5. "Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
    Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
    Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiWIP3_ARATH
AccessioniPrimary (citable) accession number: Q94AV5
Secondary accession number(s): Q9LTT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

External Data

Dasty 3

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