Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 76

Gene

At5g53140

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi137Manganese 1By similarity1
Metal bindingi137Manganese 2By similarity1
Metal bindingi138Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi299Manganese 2By similarity1
Metal bindingi338Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 76 (EC:3.1.3.16)
Short name:
AtPP2C76
Gene namesi
Ordered Locus Names:At5g53140
ORF Names:MFH8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G53140
TAIRilocus:2163781 AT5G53140

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679961 – 420Probable protein phosphatase 2C 76Add BLAST420

Proteomic databases

PaxDbiQ94AT1
PRIDEiQ94AT1

PTM databases

iPTMnetiQ94AT1

Expressioni

Gene expression databases

ExpressionAtlasiQ94AT1 baseline and differential
GenevisibleiQ94AT1 AT

Interactioni

Protein-protein interaction databases

BioGridi20640, 4 interactors
IntActiQ94AT1, 1 interactor
MINTiQ94AT1
STRINGi3702.AT5G53140.1

Structurei

3D structure databases

ProteinModelPortaliQ94AT1
SMRiQ94AT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 347PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST247

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233896
InParanoidiQ94AT1
KOiK17506
OMAiLSCGYCS
OrthoDBiEOG09360FJK
PhylomeDBiQ94AT1

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q94AT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCSSFIRSF IVQAGCRIGV LAQGRHQFIH IKKTLSVGFG FRTSVIGFRT
60 70 80 90 100
TSGIGFRTSA KMMVDTSAGE KRISLVDMPP EKVDDGGYIG GGWKNDDGSL
110 120 130 140 150
SCGYCSFRGK RSTMEDFYDI KASTIEGQAV CMFGIFDGHG GSRAAEYLKE
160 170 180 190 200
HLFNNLMKHP QFLTDTKLAL NETYKQTDVA FLESEKDTYR DDGSTASAAV
210 220 230 240 250
LVGNHLYVAN VGDSRTIVSK AGKAIALSDD HKPNRSDERK RIESAGGVIM
260 270 280 290 300
WAGTWRVGGV LAMSRAFGNR MLKQFVVAEP EIQDLEIDHE AELLVLASDG
310 320 330 340 350
LWDVVPNEDA VALAQSEEEP EAAARKLTDT AFSRGSADNI TCIVVKFRHD
360 370 380 390 400
KTESPKIETN AMAESEPELN PTTELEPESN PSTALETESI PKAELESEPD
410 420
AIPDPKPETE PETKGEKAGE
Length:420
Mass (Da):45,786
Last modified:December 1, 2001 - v1
Checksum:iC312D84D35159052
GO

Sequence cautioni

The sequence BAB08417 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti267F → L in AAM91486 (PubMed:14593172).Curated1
Sequence conflicti267F → L in AAL57666 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB025622 Genomic DNA Translation: BAB08417.1 Sequence problems.
CP002688 Genomic DNA Translation: AED96312.1
CP002688 Genomic DNA Translation: ANM68199.1
AY045819 mRNA Translation: AAK76493.1
AY065026 mRNA Translation: AAL57666.1
AY091360 mRNA Translation: AAM14299.1
AY133656 mRNA Translation: AAM91486.1
RefSeqiNP_001329972.1, NM_001345034.1
NP_568786.1, NM_124693.4
UniGeneiAt.47617

Genome annotation databases

EnsemblPlantsiAT5G53140.1; AT5G53140.1; AT5G53140
AT5G53140.2; AT5G53140.2; AT5G53140
GeneIDi835395
GrameneiAT5G53140.1; AT5G53140.1; AT5G53140
AT5G53140.2; AT5G53140.2; AT5G53140
KEGGiath:AT5G53140

Similar proteinsi

Entry informationi

Entry nameiP2C76_ARATH
AccessioniPrimary (citable) accession number: Q94AT1
Secondary accession number(s): Q8VZD9, Q9FGM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health