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Q94AT1

- P2C76_ARATH

UniProt

Q94AT1 - P2C76_ARATH

Protein

Probable protein phosphatase 2C 76

Gene

At5g53140

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi137 – 1371Manganese 1By similarity
    Metal bindingi137 – 1371Manganese 2By similarity
    Metal bindingi138 – 1381Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi299 – 2991Manganese 2By similarity
    Metal bindingi338 – 3381Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G53140-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 76 (EC:3.1.3.16)
    Short name:
    AtPP2C76
    Gene namesi
    Ordered Locus Names:At5g53140
    ORF Names:MFH8.8
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G53140.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 420420Probable protein phosphatase 2C 76PRO_0000367996Add
    BLAST

    Proteomic databases

    PaxDbiQ94AT1.
    PRIDEiQ94AT1.

    Expressioni

    Gene expression databases

    GenevestigatoriQ94AT1.

    Interactioni

    Protein-protein interaction databases

    BioGridi20640. 4 interactions.
    IntActiQ94AT1. 1 interaction.
    MINTiMINT-8390589.
    STRINGi3702.AT5G53140.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ94AT1.
    SMRiQ94AT1. Positions 100-378.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini100 – 340241PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ94AT1.
    KOiK17506.
    OMAiETYKQTD.
    PhylomeDBiQ94AT1.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q94AT1-1 [UniParc]FASTAAdd to Basket

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    MVCSSFIRSF IVQAGCRIGV LAQGRHQFIH IKKTLSVGFG FRTSVIGFRT    50
    TSGIGFRTSA KMMVDTSAGE KRISLVDMPP EKVDDGGYIG GGWKNDDGSL 100
    SCGYCSFRGK RSTMEDFYDI KASTIEGQAV CMFGIFDGHG GSRAAEYLKE 150
    HLFNNLMKHP QFLTDTKLAL NETYKQTDVA FLESEKDTYR DDGSTASAAV 200
    LVGNHLYVAN VGDSRTIVSK AGKAIALSDD HKPNRSDERK RIESAGGVIM 250
    WAGTWRVGGV LAMSRAFGNR MLKQFVVAEP EIQDLEIDHE AELLVLASDG 300
    LWDVVPNEDA VALAQSEEEP EAAARKLTDT AFSRGSADNI TCIVVKFRHD 350
    KTESPKIETN AMAESEPELN PTTELEPESN PSTALETESI PKAELESEPD 400
    AIPDPKPETE PETKGEKAGE 420
    Length:420
    Mass (Da):45,786
    Last modified:December 1, 2001 - v1
    Checksum:iC312D84D35159052
    GO

    Sequence cautioni

    The sequence BAB08417.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti267 – 2671F → L in AAM91486. (PubMed:14593172)Curated
    Sequence conflicti267 – 2671F → L in AAL57666. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB025622 Genomic DNA. Translation: BAB08417.1. Sequence problems.
    CP002688 Genomic DNA. Translation: AED96312.1.
    AY045819 mRNA. Translation: AAK76493.1.
    AY065026 mRNA. Translation: AAL57666.1.
    AY091360 mRNA. Translation: AAM14299.1.
    AY133656 mRNA. Translation: AAM91486.1.
    RefSeqiNP_568786.1. NM_124693.3.
    UniGeneiAt.47617.

    Genome annotation databases

    EnsemblPlantsiAT5G53140.1; AT5G53140.1; AT5G53140.
    GeneIDi835395.
    KEGGiath:AT5G53140.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB025622 Genomic DNA. Translation: BAB08417.1 . Sequence problems.
    CP002688 Genomic DNA. Translation: AED96312.1 .
    AY045819 mRNA. Translation: AAK76493.1 .
    AY065026 mRNA. Translation: AAL57666.1 .
    AY091360 mRNA. Translation: AAM14299.1 .
    AY133656 mRNA. Translation: AAM91486.1 .
    RefSeqi NP_568786.1. NM_124693.3.
    UniGenei At.47617.

    3D structure databases

    ProteinModelPortali Q94AT1.
    SMRi Q94AT1. Positions 100-378.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 20640. 4 interactions.
    IntActi Q94AT1. 1 interaction.
    MINTi MINT-8390589.
    STRINGi 3702.AT5G53140.1-P.

    Proteomic databases

    PaxDbi Q94AT1.
    PRIDEi Q94AT1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G53140.1 ; AT5G53140.1 ; AT5G53140 .
    GeneIDi 835395.
    KEGGi ath:AT5G53140.

    Organism-specific databases

    TAIRi AT5G53140.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q94AT1.
    KOi K17506.
    OMAi ETYKQTD.
    PhylomeDBi Q94AT1.

    Enzyme and pathway databases

    BioCyci ARA:AT5G53140-MONOMER.

    Gene expression databases

    Genevestigatori Q94AT1.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. XI."
      Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
      Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C76_ARATH
    AccessioniPrimary (citable) accession number: Q94AT1
    Secondary accession number(s): Q8VZD9, Q9FGM3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3