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Protein

Probable protein phosphatase 2C 76

Gene

At5g53140

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi137Manganese 1By similarity1
Metal bindingi137Manganese 2By similarity1
Metal bindingi138Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi299Manganese 2By similarity1
Metal bindingi338Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 76 (EC:3.1.3.16)
Short name:
AtPP2C76
Gene namesi
Ordered Locus Names:At5g53140
ORF Names:MFH8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G53140.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679961 – 420Probable protein phosphatase 2C 76Add BLAST420

Proteomic databases

PaxDbiQ94AT1.

PTM databases

iPTMnetiQ94AT1.

Expressioni

Gene expression databases

GenevisibleiQ94AT1. AT.

Interactioni

Protein-protein interaction databases

BioGridi20640. 4 interactors.
IntActiQ94AT1. 1 interactor.
MINTiMINT-8390589.
STRINGi3702.AT5G53140.1.

Structurei

3D structure databases

ProteinModelPortaliQ94AT1.
SMRiQ94AT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 347PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST247

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiQ94AT1.
KOiK17506.
OMAiPNRNDER.
OrthoDBiEOG09360FJK.
PhylomeDBiQ94AT1.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q94AT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCSSFIRSF IVQAGCRIGV LAQGRHQFIH IKKTLSVGFG FRTSVIGFRT
60 70 80 90 100
TSGIGFRTSA KMMVDTSAGE KRISLVDMPP EKVDDGGYIG GGWKNDDGSL
110 120 130 140 150
SCGYCSFRGK RSTMEDFYDI KASTIEGQAV CMFGIFDGHG GSRAAEYLKE
160 170 180 190 200
HLFNNLMKHP QFLTDTKLAL NETYKQTDVA FLESEKDTYR DDGSTASAAV
210 220 230 240 250
LVGNHLYVAN VGDSRTIVSK AGKAIALSDD HKPNRSDERK RIESAGGVIM
260 270 280 290 300
WAGTWRVGGV LAMSRAFGNR MLKQFVVAEP EIQDLEIDHE AELLVLASDG
310 320 330 340 350
LWDVVPNEDA VALAQSEEEP EAAARKLTDT AFSRGSADNI TCIVVKFRHD
360 370 380 390 400
KTESPKIETN AMAESEPELN PTTELEPESN PSTALETESI PKAELESEPD
410 420
AIPDPKPETE PETKGEKAGE
Length:420
Mass (Da):45,786
Last modified:December 1, 2001 - v1
Checksum:iC312D84D35159052
GO

Sequence cautioni

The sequence BAB08417 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti267F → L in AAM91486 (PubMed:14593172).Curated1
Sequence conflicti267F → L in AAL57666 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB025622 Genomic DNA. Translation: BAB08417.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96312.1.
AY045819 mRNA. Translation: AAK76493.1.
AY065026 mRNA. Translation: AAL57666.1.
AY091360 mRNA. Translation: AAM14299.1.
AY133656 mRNA. Translation: AAM91486.1.
RefSeqiNP_568786.1. NM_124693.4.
UniGeneiAt.47617.

Genome annotation databases

EnsemblPlantsiAT5G53140.1; AT5G53140.1; AT5G53140.
GeneIDi835395.
GrameneiAT5G53140.1; AT5G53140.1; AT5G53140.
KEGGiath:AT5G53140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB025622 Genomic DNA. Translation: BAB08417.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96312.1.
AY045819 mRNA. Translation: AAK76493.1.
AY065026 mRNA. Translation: AAL57666.1.
AY091360 mRNA. Translation: AAM14299.1.
AY133656 mRNA. Translation: AAM91486.1.
RefSeqiNP_568786.1. NM_124693.4.
UniGeneiAt.47617.

3D structure databases

ProteinModelPortaliQ94AT1.
SMRiQ94AT1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi20640. 4 interactors.
IntActiQ94AT1. 1 interactor.
MINTiMINT-8390589.
STRINGi3702.AT5G53140.1.

PTM databases

iPTMnetiQ94AT1.

Proteomic databases

PaxDbiQ94AT1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G53140.1; AT5G53140.1; AT5G53140.
GeneIDi835395.
GrameneiAT5G53140.1; AT5G53140.1; AT5G53140.
KEGGiath:AT5G53140.

Organism-specific databases

TAIRiAT5G53140.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiQ94AT1.
KOiK17506.
OMAiPNRNDER.
OrthoDBiEOG09360FJK.
PhylomeDBiQ94AT1.

Miscellaneous databases

PROiQ94AT1.

Gene expression databases

GenevisibleiQ94AT1. AT.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C76_ARATH
AccessioniPrimary (citable) accession number: Q94AT1
Secondary accession number(s): Q8VZD9, Q9FGM3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.