Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q94AT1 (P2C76_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 76

Short name=AtPP2C76
EC=3.1.3.16
Gene names
Ordered Locus Names:At5g53140
ORF Names:MFH8.8
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence BAB08417.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 420420Probable protein phosphatase 2C 76
PRO_0000367996

Regions

Domain100 – 340241PP2C-like

Sites

Metal binding1371Manganese 1 By similarity
Metal binding1371Manganese 2 By similarity
Metal binding1381Manganese 1; via carbonyl oxygen By similarity
Metal binding2991Manganese 2 By similarity
Metal binding3381Manganese 2 By similarity

Experimental info

Sequence conflict2671F → L in AAM91486. Ref.3
Sequence conflict2671F → L in AAL57666. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q94AT1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: C312D84D35159052

FASTA42045,786
        10         20         30         40         50         60 
MVCSSFIRSF IVQAGCRIGV LAQGRHQFIH IKKTLSVGFG FRTSVIGFRT TSGIGFRTSA 

        70         80         90        100        110        120 
KMMVDTSAGE KRISLVDMPP EKVDDGGYIG GGWKNDDGSL SCGYCSFRGK RSTMEDFYDI 

       130        140        150        160        170        180 
KASTIEGQAV CMFGIFDGHG GSRAAEYLKE HLFNNLMKHP QFLTDTKLAL NETYKQTDVA 

       190        200        210        220        230        240 
FLESEKDTYR DDGSTASAAV LVGNHLYVAN VGDSRTIVSK AGKAIALSDD HKPNRSDERK 

       250        260        270        280        290        300 
RIESAGGVIM WAGTWRVGGV LAMSRAFGNR MLKQFVVAEP EIQDLEIDHE AELLVLASDG 

       310        320        330        340        350        360 
LWDVVPNEDA VALAQSEEEP EAAARKLTDT AFSRGSADNI TCIVVKFRHD KTESPKIETN 

       370        380        390        400        410        420 
AMAESEPELN PTTELEPESN PSTALETESI PKAELESEPD AIPDPKPETE PETKGEKAGE 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. XI."
Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB025622 Genomic DNA. Translation: BAB08417.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96312.1.
AY045819 mRNA. Translation: AAK76493.1.
AY065026 mRNA. Translation: AAL57666.1.
AY091360 mRNA. Translation: AAM14299.1.
AY133656 mRNA. Translation: AAM91486.1.
RefSeqNP_568786.1. NM_124693.3.
UniGeneAt.47617.

3D structure databases

ProteinModelPortalQ94AT1.
SMRQ94AT1. Positions 100-378.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid20640. 4 interactions.
IntActQ94AT1. 1 interaction.
MINTMINT-8390589.
STRING3702.AT5G53140.1-P.

Proteomic databases

PaxDbQ94AT1.
PRIDEQ94AT1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G53140.1; AT5G53140.1; AT5G53140.
GeneID835395.
KEGGath:AT5G53140.

Organism-specific databases

TAIRAT5G53140.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233896.
InParanoidQ94AT1.
KOK17506.
OMAETYKQTD.
PhylomeDBQ94AT1.

Enzyme and pathway databases

BioCycARA:AT5G53140-MONOMER.

Gene expression databases

GenevestigatorQ94AT1.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C76_ARATH
AccessionPrimary (citable) accession number: Q94AT1
Secondary accession number(s): Q8VZD9, Q9FGM3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names