Reviewed, UniProtKB/Swiss-Prot Q94AL9 (AGT22_ARATH)

Names and origin

Protein names

Recommended name:
    Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial
    EC=2.6.1.44
Alternative name(s):
    Beta-alanine-pyruvate aminotransferase 2

Gene names

Name:	AGT3
Ordered Locus Names:	At2g38400
ORF Names:	T19C21.11

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	L-alanine + glyoxylate = pyruvate + glycine.
Cofactor	Pyridoxal phosphate.
Subunit structure	Homotetramer By similarity.
Subcellular location	Mitochondrion Potential.
Sequence similarities	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Biological process	Photorespiration
Cellular component	Mitochondrion
Domain	Transit peptide
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	photorespiration Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alanine-glyoxylate transaminase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 22	22	Mitochondrion Potential
	Chain	23 – 477	455	Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial		PRO_0000041946
Amino acid modifications
	Modified residue	321	1	N6-(pyridoxal phosphate)lysine By similarity
Experimental info
	Sequence conflict	461	1	D → G in AAK76615. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q94AL9-1 [UniParc]. Last modified September 13, 2005. Version 2. Checksum: FE52ACFAAAA25FCC	FASTA	477	51,912
	10 20 30 40 50 60 MQRFAAKRSV QNISVSLWRR CISSTSQAAT ASVKDSDEFQ ARLPPFAYTP PPYTGPSADV 70 80 90 100 110 120 ILSKRKEFLS PSMFCLYRKP LNIVDGKMQY LFDESGRRYL DAFAGIAVVN CGHCHPDVVE 130 140 150 160 170 180 PVINQIKRLQ HPTVLYLNHA IADFSEALAS KLPGDLKVVF FTNSGTEANE LALMMAKLYT 190 200 210 220 230 240 GCQDIVAVRN GYHGNAAATM GATGQSMWKF NVVQNSVHHA LNPDPYRGVF GSDGEKYAKD 250 260 270 280 290 300 LQDLIQYGTT GHIAGFICEA IQGVGGIVEL APGYLSAAYD TVKKAGGLFI ADEVQSGFAR 310 320 330 340 350 360 TGNFWGFEAH NVVPDIVTMA KGIGNGFPLG AVVTTPEIAG VLTRRSYFNT FGGNSVSTTA 370 380 390 400 410 420 GLAVLNVIEK EKLQENAAMV GSYLKEKLTQ LKEKHEIIGD VRGRGLMLGV ELVSDRKLKT 430 440 450 460 470 PATAETLHIM DQMKELGVLI GKGGYFGNVF RITPPLCFTK DDADFLVEAM DYSMSKM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis." Liepman A.H., Olsen L.J. Plant Physiol. 131:215-227(2003) [PubMed: 12529529] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF166352 mRNA. Translation: AAD48838.1. AC004683 Genomic DNA. Translation: AAC28764.1. AY045941 mRNA. Translation: AAK76615.1. BT001918 mRNA. Translation: AAN71917.1. AY085348 mRNA. Translation: AAM62579.1.
IPI	IPI00535694.
PIR	T02505.
RefSeq	NP_181374.1.
UniGene	At.11529
3D structure databases
HSSP	HSSP built from PDB template 2DKB based on UniProtKB P16932.
ModBase	Search...
Protein-protein interaction databases
STRING	Q94AL9.
Proteomic databases
PRIDE	Q94AL9.
Genome annotation databases
GeneID	818421.
GenomeReviews	Gene locus AT2G38400 in contig CT485783_GR.
KEGG	ath:AT2G38400.
NMPDR	fig|3702.1.peg.10953.
Organism-specific databases
GeneFarm	5078. 483.
TAIR	At2g38400.
Phylogenomic databases
OMA	NGYHGNA.
Enzyme and pathway databases
BRENDA	2.6.1.44. 302.
Gene expression databases
Genevestigator	Q94AL9.
GermOnline	AT2G38400. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR005814. Aminotrans_3. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
PANTHER	PTHR11986. Aminotrans_3. 1 hit.
Pfam	PF00202. Aminotran_3. 1 hit. [Graphical view]
PROSITE	PS00600. AA_TRANSFER_CLASS_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGT22_ARATH

Accession

Primary (citable) accession number: Q94AL9
Secondary accession number(s): O80911

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)