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Q94AB5 (U7E12_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-glycosyltransferase 76E12

EC=2.4.1.-
EC=2.4.1.91
Gene names
Name:UGT76E12
Ordered Locus Names:At3g46660
ORF Names:F12A12.180
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Possesses quercetin 3-O-glucosyltransferase and 7-O-glucosyltransferase activities in vitro. Ref.5

Catalytic activity

UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.

UDP-glucose + a flavonol = UDP + a flavonol 7-O-D-glucoside.

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Sequence caution

The sequence CAB62336.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 458458UDP-glycosyltransferase 76E12
PRO_0000409095

Regions

Region339 – 3413UDP-glucose binding By similarity
Region356 – 3649UDP-glucose binding By similarity
Region378 – 3814UDP-glucose binding By similarity

Sites

Binding site2801UDP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q94AB5 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 064AC578C026B098

FASTA45851,662
        10         20         30         40         50         60 
MQVLGMEEKP ARRSVVLVPF PAQGHISPMM QLAKTLHLKG FSITVVQTKF NYFSPSDDFT 

        70         80         90        100        110        120 
HDFQFVTIPE SLPESDFKNL GPIQFLFKLN KECKVSFKDC LGQLVLQQSN EISCVIYDEF 

       130        140        150        160        170        180 
MYFAEAAAKE CKLPNIIFST TSATAFACRS VFDKLYANNV QAPLKETKGQ QEELVPEFYP 

       190        200        210        220        230        240 
LRYKDFPVSR FASLESIMEV YRNTVDKRTA SSVIINTASC LESSSLSFLQ QQQLQIPVYP 

       250        260        270        280        290        300 
IGPLHMVASA PTSLLEENKS CIEWLNKQKV NSVIYISMGS IALMEINEIM EVASGLAASN 

       310        320        330        340        350        360 
QHFLWVIRPG SIPGSEWIES MPEEFSKMVL DRGYIVKWAP QKEVLSHPAV GGFWSHCGWN 

       370        380        390        400        410        420 
STLESIGQGV PMICRPFSGD QKVNARYLEC VWKIGIQVEG ELDRGVVERA VKRLMVDEEG 

       430        440        450 
EEMRKRAFSL KEQLRASVKS GGSSHNSLEE FVHFIRTL 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Phylogenetic analysis of the UDP-glycosyltransferase multigene family of Arabidopsis thaliana."
Li Y., Baldauf S., Lim E.K., Bowles D.J.
J. Biol. Chem. 276:4338-4343(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
[5]"Arabidopsis glycosyltransferases as biocatalysts in fermentation for regioselective synthesis of diverse quercetin glucosides."
Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.
Biotechnol. Bioeng. 87:623-631(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL133314 Genomic DNA. Translation: CAB62336.1. Different initiation.
CP002686 Genomic DNA. Translation: AEE78190.1.
AY048297 mRNA. Translation: AAK82559.1.
AY120731 mRNA. Translation: AAM53289.1.
BT000356 mRNA. Translation: AAN15675.1.
BT002638 mRNA. Translation: AAO11554.1.
PIRT45603.
RefSeqNP_566885.1. NM_114533.2.
UniGeneAt.600.

3D structure databases

ProteinModelPortalQ94AB5.
SMRQ94AB5. Positions 15-452.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT3G46660.1-P.

Protein family/group databases

CAZyGT1. Glycosyltransferase Family 1.

Proteomic databases

PRIDEQ94AB5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G46660.1; AT3G46660.1; AT3G46660.
GeneID823819.
KEGGath:AT3G46660.

Organism-specific databases

TAIRAT3G46660.

Phylogenomic databases

eggNOGNOG326467.
HOGENOMHOG000237564.
InParanoidQ94AB5.
OMAINEIMEV.
PhylomeDBQ94AB5.

Gene expression databases

ArrayExpressQ94AB5.
GenevestigatorQ94AB5.

Family and domain databases

InterProIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERPTHR11926. PTHR11926. 1 hit.
PfamPF00201. UDPGT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameU7E12_ARATH
AccessionPrimary (citable) accession number: Q94AB5
Secondary accession number(s): Q9SNB2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names