Q949M2 (FABG4_BRANA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase 4
EC=1.1.1.100

Alternative name(s):
3-ketoacyl-acyl carrier protein reductase 4

Gene names

Name:

bkr4

Organism

Brassica napus (Rape)

Taxonomic identifier

3708 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Brassiceae › Brassica

Protein attributes

Sequence length	254 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Subunit structure	Homotetramer By similarity.
Subcellular location	Plastid › chloroplast By similarity. Plastid By similarity. Note: And non-photosynthetic plastids By similarity.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Cellular component	Chloroplast Plastid
Ligand	NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Inferred from electronic annotation. Source: EC NAD binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 254	›254	3-oxoacyl-[acyl-carrier-protein] reductase 4		PRO_0000054660
Regions
	Nucleotide binding	19 – 43	25	NADP By similarity
Sites
	Active site	161	1	Proton acceptor By similarity
	Binding site	148	1	Substrate By similarity
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q949M2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: F903A899E3FAB2C6	FASTA	254	26,648
	10 20 30 40 50 60 TTTEEEEAVP KVESPVVVVT GASRGIGKAI ALSLGKAGCK VLVNYARSAK EAEEVSKQIE 70 80 90 100 110 120 EYGGQAITFG GDVSKEADVD AMMKTAVDKW GTIDVVVNNA GDTLLIRMKK SQWDEVMDLN 130 140 150 160 170 180 LTGVFLCSQA ATKIMMKKRK GRIINIASVV GLIGNIGQAN YAAAKAGVIG FSKTAAREGA 190 200 210 220 230 240 SRNINVNVVC PGFIASDMTA KLGEDMEKKI LGTIPLGRYG QPEDVAGLVE FLALSPAASY 250 ITGQTFTIDG GIAI

References

[1]	McDonald F.S., White A.J., Elborough K.M., Slabas A.R. Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Jet neuf. Tissue: Embryo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ243086 mRNA. Translation: CAC41365.1.
3D structure databases
ProteinModelPortal	Q949M2.
SMR	Q949M2. Positions 14-254.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00094.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR011284. 3oxo_ACP_reduc. IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH. PR00080. SDRFAMILY.
TIGRFAMs	TIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FABG4_BRANA

Accession

Primary (citable) accession number: Q949M2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	December 1, 2001
Last modified:	March 6, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program