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Q949M2 (FABG4_BRANA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] reductase 4

EC=1.1.1.100
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase 4
Gene names
Name:bkr4
OrganismBrassica napus (Rape)
Taxonomic identifier3708 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Protein attributes

Sequence length254 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathway

Lipid metabolism; fatty acid biosynthesis.

Subunit structure

Homotetramer By similarity.

Subcellular location

Plastidchloroplast By similarity. Plastid By similarity. Note: And non-photosynthetic plastids By similarity.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Cellular componentChloroplast
Plastid
   LigandNADP
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

Inferred from electronic annotation. Source: UniProtKB-EC

NAD binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 254›2543-oxoacyl-[acyl-carrier-protein] reductase 4
PRO_0000054660

Regions

Nucleotide binding19 – 4325NADP By similarity

Sites

Active site1611Proton acceptor By similarity
Binding site1481Substrate By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q949M2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: F903A899E3FAB2C6

FASTA25426,648
        10         20         30         40         50         60 
TTTEEEEAVP KVESPVVVVT GASRGIGKAI ALSLGKAGCK VLVNYARSAK EAEEVSKQIE 

        70         80         90        100        110        120 
EYGGQAITFG GDVSKEADVD AMMKTAVDKW GTIDVVVNNA GDTLLIRMKK SQWDEVMDLN 

       130        140        150        160        170        180 
LTGVFLCSQA ATKIMMKKRK GRIINIASVV GLIGNIGQAN YAAAKAGVIG FSKTAAREGA 

       190        200        210        220        230        240 
SRNINVNVVC PGFIASDMTA KLGEDMEKKI LGTIPLGRYG QPEDVAGLVE FLALSPAASY 

       250 
ITGQTFTIDG GIAI 

« Hide

References

[1]McDonald F.S., White A.J., Elborough K.M., Slabas A.R.
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Jet neuf.
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ243086 mRNA. Translation: CAC41365.1.

3D structure databases

ProteinModelPortalQ949M2.
SMRQ949M2. Positions 14-254.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFABG4_BRANA
AccessionPrimary (citable) accession number: Q949M2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways