Q948Z4 (SNAK1_SOLTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Snakin-1

Gene names

Name:

SN1

Organism

Solanum tuberosum (Potato)

Taxonomic identifier

4113 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	88 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has an antimicrobial activity. Causes a rapid aggregation of both Gram-positive and Gram-negative bacteria, but the antimicrobial activity is not correlated with the capacity to aggregate bacteria. Ref.1
Subcellular location	Secreted › cell wall.
Tissue specificity	Expressed in tubers, stems, axillary and young floral buds, sepals, petals, stamens and carpels, but not in roots, stolons, shoot apex meristem or young leaves. Ref.1
Induction	No responses to methyl jasmonate, ethylene, abscisic acid, salicylic acid, isonicotinic acid, indolacetic acid, gibberellic acid and infection with incompatible bacterial or compatible fungual pathogens. Ref.1
Post-translational modification	Six disulfide bonds may be present.
Sequence similarities	Belongs to the GASA family.

Ontologies

Keywords
Biological process	Plant defense
Cellular component	Cell wall Secreted
Domain	Signal
Molecular function	Antimicrobial
PTM	Disulfide bond
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	defense response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 88	63	Snakin-1		PRO_0000348599
Regions
	Compositional bias	30 – 74	45	Cys-rich
Experimental info
	Sequence conflict	28	1	S → N AA sequence Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q948Z4 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 0F31E83EF61E7D09	FASTA	88	9,664
	10 20 30 40 50 60 MKLFLLTLLL VTLVITPSLI QTTMAGSSFC DSKCKLRCSK AGLADRCLKY CGICCEECKC 70 80 VPSGTYGNKH ECPCYRDKKN SKGKSKCP

References

[1]	"Snakin-1, a peptide from potato that is active against plant pathogens." Segura A., Moreno M., Madueno F., Molina A., Garcia-Olmedo F. Mol. Plant Microbe Interact. 12:16-23(1999) [PubMed: 9885189] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 26-60, FUNCTION, TISSUE SPECIFICITY, INDUCTION. Strain: cv. Jaerla. Tissue: Tuber.
[2]	Berrocal Lobo M. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF014396 mRNA. Translation: AAD01518.1. AJ320185 Genomic DNA. Translation: CAC44032.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR003854. GASA. [Graphical view]
Pfam	PF02704. GASA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SNAK1_SOLTU

Accession

Primary (citable) accession number: Q948Z4
Secondary accession number(s): Q9ZTX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	December 1, 2001
Last modified:	September 22, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program