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Q948P5 (FRI4_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin-4, chloroplastic

EC=1.16.3.1
Alternative name(s):
SFerH-4
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length247 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.

Subcellular location

Plastidchloroplast By similarity.

Sequence similarities

Belongs to the ferritin family.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

iron ion transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 4040Chloroplast Potential
Chain41 – 247207Ferritin-4, chloroplastic
PRO_0000008867

Regions

Domain74 – 227154Ferritin-like diiron
Region41 – 7333Extension peptide (EP)

Sites

Metal binding911Iron 1 By similarity
Metal binding1261Iron 1 By similarity
Metal binding1261Iron 2 By similarity
Metal binding1291Iron 1 By similarity
Metal binding1751Iron 2 By similarity
Metal binding2091Iron 2 By similarity

Secondary structure

.................... 247
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q948P5 [UniParc].

Last modified September 22, 2009. Version 2.
Checksum: 9A643DDFB5DDEDE3

FASTA24727,559
        10         20         30         40         50         60 
MLLRTAAASA SSLSLFSPNA EPPRSVPARG LVVRAAKGST NHRALTGVIF EPFEEVKKEL 

        70         80         90        100        110        120 
DLVPTVPQAS LARQKYVDES ESAVNEQINV EYNVSYVYHA MFAYFDRDNV ALRGLAKFFK 

       130        140        150        160        170        180 
ESSEEEREHA EKLMEYQNKR GGKVKLQSIV MPLSDFDHAD KGDALHAMEL ALSLEKLTNE 

       190        200        210        220        230        240 
KLLNLHSVAT KNGDVQLADF VETEYLGEQV EAIKRISEYV AQLRRVGKGH GVWHFDQMLL 


HEGGDAA 

« Hide

References

[1]"Construction of homo- and heteropolymers of plant ferritin subunits using an in vitro protein expression system."
Masuda T., Goto F., Yoshihara T., Ezure T., Suzuki T., Kobayashi S., Shikata M., Utsumi S.
Protein Expr. Purif. 56:237-246(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB062756 mRNA. Translation: BAB64537.2.
RefSeqNP_001237049.1. NM_001250120.1.
UniGeneGma.18301.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3A68X-ray1.80A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X36-247[»]
3A9QX-ray1.90A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X36-247[»]
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ948P5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsGLYMA14G06160.1; GLYMA14G06160.1; GLYMA14G06160.
GeneID547477.
KEGGgmx:547477.

Phylogenomic databases

KOK00522.
OMAASEERTH.

Gene expression databases

GenevestigatorQ948P5.

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ948P5.

Entry information

Entry nameFRI4_SOYBN
AccessionPrimary (citable) accession number: Q948P5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: September 22, 2009
Last modified: June 11, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references