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Protein
Submitted name:

Dilute class unconventional myosin

Gene

didum

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi117 – 124ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • actin binding Source: FlyBase
  • actin-dependent ATPase activity Source: FlyBase
  • ATPase activity, coupled Source: FlyBase
  • ATP binding Source: FlyBase
  • calcium-dependent ATPase activity Source: FlyBase
  • calmodulin binding Source: FlyBase
  • microtubule binding Source: InterPro
  • microtubule motor activity Source: InterPro
  • myosin light chain binding Source: FlyBase

GO - Biological processi

  • actin filament-based movement Source: FlyBase
  • anterior/posterior axis specification, embryo Source: FlyBase
  • intracellular protein transport Source: FlyBase
  • mitochondrion transport along microtubule Source: FlyBase
  • positive regulation of pole plasm oskar mRNA localization Source: FlyBase
  • rhabdomere development Source: FlyBase
  • sperm individualization Source: FlyBase

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-432040 Vasopressin regulates renal water homeostasis via Aquaporins

Names & Taxonomyi

Protein namesi
Submitted name:
Dilute class unconventional myosinImported
Gene namesi
Name:didumImported
ORF Names:CG2146Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0261397 didum

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ94882

Expressioni

Gene expression databases

BgeeiFBgn0261397
ExpressionAtlasiQ94882 baseline and differential

Interactioni

GO - Molecular functioni

  • actin binding Source: FlyBase
  • calmodulin binding Source: FlyBase
  • microtubule binding Source: InterPro
  • myosin light chain binding Source: FlyBase

Structurei

3D structure databases

ProteinModelPortaliQ94882
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 724Myosin motorInterPro annotationAdd BLAST702
Domaini1419 – 1695DiluteInterPro annotationAdd BLAST277

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni603 – 625Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili869 – 910Sequence analysisAdd BLAST42
Coiled coili938 – 1011Sequence analysisAdd BLAST74
Coiled coili1018 – 1038Sequence analysisAdd BLAST21
Coiled coili1103 – 1130Sequence analysisAdd BLAST28
Coiled coili1140 – 1160Sequence analysisAdd BLAST21
Coiled coili1167 – 1187Sequence analysisAdd BLAST21
Coiled coili1231 – 1276Sequence analysisAdd BLAST46

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0161 Eukaryota
COG5022 LUCA
OrthoDBiEOG091G0G93

Family and domain databases

CDDicd01380 MYSc_Myo5, 1 hit
Gene3Di3.40.850.10, 3 hits
InterProiView protein in InterPro
IPR002710 Dilute_dom
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR036103 MYSc_Myo5
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01843 DIL, 1 hit
PF00612 IQ, 4 hits
PF00063 Myosin_head, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM01132 DIL, 1 hit
SM00015 IQ, 6 hits
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51126 DILUTE, 1 hit
PS50096 IQ, 5 hits
PS51456 MYOSIN_MOTOR, 1 hit

Sequencei

Sequence statusi: Fragment.

Q94882-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VKEVELKADG SDLPPLRNPA ILVGQNDLTT LSYLHEPGVL HNLRVRFCKR
60 70 80 90 100
QIIYTYCGII LVAINPYAEM PLYGPSIIRA YRGHAMGDLE PHIFALAEEA
110 120 130 140 150
YTKLERENCN LSIIVSGESG AGKTVSAKYA MRYFAAVGGS ESETQVERKV
160 170 180 190 200
LASSPIMEAF GNAKTTRNDN SSRFGKFTNL LFRNQMGVMF LQGPTMHTYL
210 220 230 240 250
LEKSRVVYQA QGDRNYHIFY QLCAARSKYP ELVLDHQDKF QFLNMGGAPE
260 270 280 290 300
IERVSDAEQF NETVQAMTVL GFSIQQIADI VKILAGILHL GNIQVSKKFN
310 320 330 340 350
EGSEEEDSDS CDIFHNDIHL QITADLLRVS ADDLRRWLLM RKIESVNEYV
360 370 380 390 400
LIPNSIEAAQ AARDALAKHI YAKLFQYIVG VLNKSLNNGS KQCSFIGVLD
410 420 430 440 450
IYGFETFEVN SFEQFCINYA NEKLQQQFNQ HVFKLEQEEY LKEGITWTMI
460 470 480 490 500
DFYDNQPCID LIESRLGVLD LLDEECRMPK GSDESWAGKL IGKCNKFPHF
510 520 530 540 550
EKPRFGTTSF FIKHFSDTVE YDVNGFLEKN RDTVSKELTQ VLSESNMSLA
560 570 580 590 600
KQVMTLEEID TLCVDSAKSS TLGGRVVISA GRKQVVPSKQ HRKTVGSQFQ
610 620 630 640 650
ESLASLISTL HATTPHYVRC IKPNDDKVAF KWETAKIIQQ LRACGVLETV
660 670 680 690 700
RISAAGFPSR WLYPDFYMRY QLLVYRSKLD KNDMRLSCRN IVMKWIQDED
710 720 730 740 750
KYRFGNTQIF FRAGQVAFLE QVRANLRKKY ITIVQSVVRR FVYRRQVLRI
760 770 780 790 800
QKVINGIQKH ARGYLARERT QKMREARAGL ILSKYARGWL CRRRYLRLRH
810 820 830 840 850
SISGIQTYAR GMLARNKFHA MRDHYRAVQI QRFVRGALAR RAYQKRRRNI
860 870 880 890 900
IICQAAIRRF LARRKFKRMK AEAKTISHME NKYMGLENKI ISMQQRIDEL
910 920 930 940 950
NRDNSNLKHK TSEISVLKMK LELKKTLEAE FKNVKAACQD KDKLIEALNK
960 970 980 990 1000
QLEAERDEKM QLLEENGHAQ EEWISQKQTW RQENEELRRQ IDEIIDMAKN
1010 1020 1030 1040 1050
AEVNQRNQED RMLAEIDNRE LNEAYQRAIK DKEVIENENF MLKEELSRLT
1060 1070 1080 1090 1100
AGSFSLHGRK ASNASSQNED DVGYASAKNT LDINRPPDLL SKNYSYNDST
1110 1120 1130 1140 1150
SLVVKLRSIL EEEKQKHKVL QEQYIKLSSR HKPTEDSFRV SELEVENEKL
1160 1170 1180 1190 1200
RRRYDQLRTS IKHGVEINEL NAQHAALQEE VRRRREECIQ LKAVLLQQSQ
1210 1220 1230 1240 1250
SMRSLEPESL QMRGNDVNEL MEAFHSQKLI NRQLESELKA ITEEHNSKLV
1260 1270 1280 1290 1300
EMTQEIERLN NEKDELQKVM FESIDEFEDS NVDTLRQNDR YLRRELQKAV
1310 1320 1330 1340 1350
AQFLLVQEEL KLANAKLKAY RQDGGQLEHK IEEEMIRNKS NGTSADVGAN
1360 1370 1380 1390 1400
VTKQKSQNPQ GLMKFHSSDL DKILQRLLSA LTPRTVVGLL PGFPAYLIFM
1410 1420 1430 1440 1450
CIRYTDLTNA DDDVRELLSK FVIQIKKMHR TPHPIENRVI WLVNSITLLN
1460 1470 1480 1490 1500
LMKQYGDVDE YVKFNTEKQN QQQLKNFNLF EYRRVILDLF VNLYQALIMQ
1510 1520 1530 1540 1550
IQGLLDPKIV PAILNNDEIQ RGRQAHGMRS RATSIGASSS PEHGGGPAWK
1560 1570 1580 1590 1600
QLIGQLEHFY KQFQHFGLDN CYAEQIFHQL LYFICAVALN CLMLRGDICI
1610 1620 1630 1640 1650
WETGMIIRYN IGCIEDWVRS KKMSNDVLTA LAPLNQVSQL LQSRKSEQDV
1660 1670 1680 1690 1700
QTICDLCTSL STAQVLKVMK SYKLDDYESE ITNVFLEKLT EKLNARQMQK
1710 1720 1730 1740
SNSDEFTIDQ KFIQPFKVVF RYSDIKLEDI ELPSHLNLDE FLTKI
Length:1,745
Mass (Da):202,106
Last modified:July 5, 2004 - v4
Checksum:iC2A087271EBD6F2C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08160 mRNA Translation: CAA69352.1

Similar proteinsi

Entry informationi

Entry nameiQ94882_DROME
AccessioniPrimary (citable) accession number: Q94882
Secondary accession number(s): O01381
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 119 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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