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Protein

Intron-encoded endonuclease I-PpoI

Gene
N/A
Organism
Physarum polycephalum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Mediates the homing of a group I intron in the ribosomal DNA. Makes a four-base staggered cut in its ribosomal DNA target sequence.

Cofactori

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Intron homing

Keywords - Ligandi

Zinc

Protein family/group databases

REBASEi2469. I-PpoI.

Names & Taxonomyi

Protein namesi
Recommended name:
Intron-encoded endonuclease I-PpoI (EC:3.1.-.-)
Short name:
I-Ppo
OrganismiPhysarum polycephalum (Slime mold)
Taxonomic identifieri5791 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaMyxogastriaMyxogastromycetidaePhysariidaPhysaraceaePhysarum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001927881 – 163Intron-encoded endonuclease I-PpoIAdd BLAST163

Interactioni

Subunit structurei

Homodimer.

Structurei

Secondary structure

1163
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 19Combined sources15
Beta strandi24 – 32Combined sources9
Beta strandi35 – 43Combined sources9
Beta strandi46 – 48Combined sources3
Beta strandi54 – 58Combined sources5
Beta strandi61 – 68Combined sources8
Beta strandi71 – 76Combined sources6
Turni77 – 79Combined sources3
Helixi80 – 82Combined sources3
Beta strandi83 – 85Combined sources3
Beta strandi87 – 89Combined sources3
Beta strandi92 – 98Combined sources7
Helixi108 – 110Combined sources3
Beta strandi111 – 115Combined sources5
Helixi116 – 121Combined sources6
Helixi122 – 124Combined sources3
Turni128 – 131Combined sources4
Beta strandi157 – 160Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A73X-ray1.80A/B1-163[»]
1A74X-ray2.20A/B1-163[»]
1CYQX-ray1.93A/B2-163[»]
1CZ0X-ray2.10A/B2-163[»]
1EVWX-ray3.10A/B/C/D1-163[»]
1EVXX-ray2.00A/B2-163[»]
1IPPX-ray2.20A/B1-163[»]
2O6MX-ray2.30A/B1-163[»]
ProteinModelPortaliQ94702.
SMRiQ94702.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ94702.

Family & Domainsi

Family and domain databases

InterProiIPR008704. Endonuclease_Zinc-binding_loop.
[Graphical view]
PfamiPF05551. zf-His_Me_endon. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q94702-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTNAQILA VIDSWEETVG QFPVITHHVP LGGGLQGTLH CYEIPLAAPY
60 70 80 90 100
GVGFAKNGPT RWQYKRTINQ VVHRWGSHTV PFLLEPDNIN GKTCTASHLC
110 120 130 140 150
HNTRCHNPLH LCWESLDDNK GRNWCPGPNG GCVHAVVCLR QGPLYGPGAT
160
VAGPQQRGSH FVV
Length:163
Mass (Da):17,789
Last modified:December 15, 1998 - v3
Checksum:iA193B6F06B0D8EEF
GO

Sequence cautioni

The sequence AAB65764 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38131 Genomic DNA. Translation: AAB65765.1.
M38131 Genomic DNA. Translation: AAB65764.1. Different initiation.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38131 Genomic DNA. Translation: AAB65765.1.
M38131 Genomic DNA. Translation: AAB65764.1. Different initiation.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1A73X-ray1.80A/B1-163[»]
1A74X-ray2.20A/B1-163[»]
1CYQX-ray1.93A/B2-163[»]
1CZ0X-ray2.10A/B2-163[»]
1EVWX-ray3.10A/B/C/D1-163[»]
1EVXX-ray2.00A/B2-163[»]
1IPPX-ray2.20A/B1-163[»]
2O6MX-ray2.30A/B1-163[»]
ProteinModelPortaliQ94702.
SMRiQ94702.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

REBASEi2469. I-PpoI.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ94702.

Family and domain databases

InterProiIPR008704. Endonuclease_Zinc-binding_loop.
[Graphical view]
PfamiPF05551. zf-His_Me_endon. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPPO1_PHYPO
AccessioniPrimary (citable) accession number: Q94702
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: November 2, 2016
This is version 63 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.